Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Insulin and IGFs Enhance Hepatocyte Differentiation from Human Embryonic Stem Cells via the PI3K/AKT Pathway. 2013 Stem Cells
Functional impacts of NRXN1 knockdown on neurodevelopment in stem cell models. 2013 PLoS One
Directed differentiation of human embryonic stem cells into corticofugal neurons uncovers heterogeneous fezf2-expressing subpopulations. 2013 PLoS One
miR-294/miR-302 Promotes Proliferation, Suppresses G1-S Restriction Point, and Inhibits ESC Differentiation through Separable Mechanisms. 2013 Cell Rep
Performance and limitations of positron emission tomography (PET) scanners for imaging very low activity sources. 2013 Phys Med
Performance and limitations of positron emission tomography (PET) scanners for imaging very low activity sources. 2013 Phys Med
miR-294/miR-302 Promotes Proliferation, Suppresses G1-S Restriction Point, and Inhibits ESC Differentiation through Separable Mechanisms. 2013 Cell Rep
Analysis of protein-coding mutations in hiPSCs and their possible role during somatic cell reprogramming. 2013 Nat Commun
Insulin and IGFs Enhance Hepatocyte Differentiation from Human Embryonic Stem Cells via the PI3K/AKT Pathway. 2013 Stem Cells
Tissue specificity of decellularized rhesus monkey kidney and lung scaffolds. 2013 PLoS One
Klf4 Organizes Long-Range Chromosomal Interactions with the Oct4 Locus in Reprogramming and Pluripotency. 2013 Cell Stem Cell
Functional impacts of NRXN1 knockdown on neurodevelopment in stem cell models. 2013 PLoS One
A "living bioreactor" for the production of tissue-engineered small intestine. 2013 Methods Mol Biol
Directed differentiation of human embryonic stem cells into corticofugal neurons uncovers heterogeneous fezf2-expressing subpopulations. 2013 PLoS One
Factors affecting the structure and maturation of human tissue engineered skeletal muscle. 2013 Biomaterials
Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells. 2013 Nature
Use of "MGE Enhancers" for Labeling and Selection of Embryonic Stem Cell-Derived Medial Ganglionic Eminence (MGE) Progenitors and Neurons. 2013 PLoS One
Kinetic Analysis of npBAF to nBAF Switching Reveals Exchange of SS18 with CREST and Integration with Neural Developmental Pathways. 2013 J Neurosci
Stage-specific regulation of reprogramming to induced pluripotent stem cells by wnt signaling and T cell factor proteins. 2013 Cell Rep
BMI1 represses Ink4a/Arf and Hox genes to regulate stem cells in the rodent incisor. 2013 Nat Cell Biol
Functional Maturation of hPSC-Derived Forebrain Interneurons Requires an Extended Timeline and Mimics Human Neural Development. 2013 Cell Stem Cell
GABA progenitors grafted into the adult epileptic brain control seizures and abnormal behavior. 2013 Nat Neurosci
Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1gamma in reprogramming to pluripotency. 2013 Nat Cell Biol
Nuclear factor one b regulates neural stem cell differentiation and axonal projection of corticofugal neurons. 2013 J Comp Neurol
Intrachromosomal Looping Is Required for Activation of Endogenous Pluripotency Genes during Reprogramming. 2013 Cell Stem Cell
Hypoxia and trophoblast differentiation: a key role for PPARgamma 2013 Stem Cells Dev
An indirect approach to generating specific human cell types. 2013 Nat Methods
Mechanism-Based Facilitated Maturation of Human Pluripotent Stem Cell-Derived Cardiomyocytes. 2013 Circ Arrhythm Electrophysiol
Transcriptome sequencing of tumor subpopulations reveals a spectrum of therapeutic options for squamous cell lung cancer. 2013 PLoS One
TYK2-STAT1-BCL2 Pathway Dependence in T-cell Acute Lymphoblastic Leukemia. 2013 Cancer Discov
A Pan-BCL2 inhibitor renders bone-marrow-resident human leukemia stem cells sensitive to tyrosine kinase inhibition. 2013 Cell Stem Cell
A far downstream enhancer for murine Bcl11b controls its T-cell specific expression. 2013 Blood
Natural Killer Cell-Activating Receptor NKG2D Mediates Innate Immune Targeting of Allogeneic Neural Progenitor Cell Grafts. 2013 Stem Cells
Wnt-Dependent Epithelial Transitions Drive Pharyngeal Pouch Formation. 2013 Dev Cell
Using shape effects to target antibody-coated nanoparticles to lung and brain endothelium. 2013 Proc Natl Acad Sci U S A
Oct4 Cell-Autonomously Promotes Primitive Endoderm Development in the Mouse Blastocyst. 2013 Dev Cell
Perivascular support of human hematopoietic stem/progenitor cells. 2013 Blood
Bivalent Chromatin Marks Developmental Regulatory Genes in the Mouse Embryonic Germline In Vivo. 2013 Cell Rep
Endogenous mammalian histone H3.3 exhibits chromatin-related functions during development. 2013 Epigenetics Chromatin
Highly Efficient Differentiation of Functional Hepatocytes From Human Induced Pluripotent Stem Cells. 2013 Stem Cells Transl Med
Efficient Generation of Astrocytes From Human Pluripotent Stem Cells in Defined Conditions. 2013 Stem Cells
Minimally invasive bipolar fractional radiofrequency treatment upregulates anti-senescence pathways. 2013 Lasers Surg Med
Generation of Functional Thymic Epithelium from Human Embryonic Stem Cells that Supports Host T Cell Development. 2013 Cell Stem Cell
beta2-Microglobulin-free HLA-G activates natural killer cells by increasing cytotoxicity and proinflammatory cytokine production. 2013 Hum Immunol
Gold Nanoparticle-Loaded Neural Stem Cells for Photothermal Ablation of Cancer. 2013 Adv Healthc Mater
Regenerative Capacity of Old Muscle Stem Cells Declines without Significant Accumulation of DNA Damage. 2013 PLoS One
Lysophosphatidic Acid Mediates Myeloid Differentiation within the Human Bone Marrow Microenvironment. 2013 PLoS One
Myc binds the pluripotency factor Utf1 through the basic-helix-loop-helix leucine zipper domain. 2013 Biochem Biophys Res Commun
In vivo response to dynamic hyaluronic acid hydrogels. 2013 Acta Biomater
Neuroglobin expression in neurogenesis. 2013 Neurosci Lett

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© 2013 California Institute for Regenerative Medicine