Stanford University

Total Awards: 
89
Award Value: 
$297,351,008
Major Facility Name: 
Lorry I. Lokey Stem Cell Research Building
Institution type: 
Not for profit

Awards to the Institution

Award Value
Basic Biology I: Helen Blau Molecular determinants of neural stem cell differentiation $1,408,332
Basic Biology I: Julien Sage Epigenetic pre-programming of human ES cells that leads to differentiation bias $1,363,171
Disease Team Research I: Alfred Lane Pre-Clinical Development of Stem Cell-Based Replacement Therapies for Stroke $11,039,208
Disease Team Research I: Alfred Lane Directed differentiation of MSCs by a novel biologic to promote cartilage repair $11,039,208
Disease Team Research I: Alfred Lane Stem Cells for Treating Pre-Arthritic Focal Cartilage Defects $11,039,208
Disease Team Research I: Gary Steinberg Autologous Delivery of Pim-1 Enhanced Cardiac Stem Cells: A Novel Clinical Therapy for Cardiac Muscle Regeneration Post MI $20,000,000
Disease Team Research I: Irving Weissman Stem cell therapies for Huntington’s Disease and other neurodegenerative disorders $18,759,276
Disease Team Research I: Irving Weissman Stem Cell-Based Targeted Immune Therapy for Cancer $18,759,276
Basic Biology II: Steven Artandi Dissecting Pathways of p53-Mediated Inhibition of Cellular Reprogramming $931,285
Basic Biology II: Steven Artandi Tumorigenicity of normal and aneuploid human embryonic and induced-pluripotent stem cells $931,285
Basic Biology II: Steven Artandi The functional role of protein O-GlcNAcylation in hESC pluripotency and differentiation $931,285
Basic Biology I: Julien Sage Mathematic Optimization of Multiple Signals for Stem Cell Differentiation into Hepatocytes $1,363,171
Basic Biology I: Julien Sage The Role of Heterochromatin in Stem Cell Differentiation and Reprogramming $1,363,171
Basic Biology I: Helen Blau Recreating the nuclear reprogramming of embryonic stem cells in vitro. $1,408,332
Basic Biology I: Helen Blau Molecular Mechanisms Controlling Human Hematopoietic Stem Cell Aging $1,408,332
Basic Biology I: Helen Blau Oncogenicity and function of mosaically aneuploid human stem cells $1,408,332
Basic Biology I: Helen Blau Identification, isolation and characterization of precursor germ cells from human pluripotent cells $1,408,332
Basic Biology I: Helen Blau Deciphering intracellular signaling mechanisms in initial differentiation of hESC $1,408,332
Basic Biology I: Helen Blau MECHANISMS OF BLOCKED iPS GENERATION IN HPRT-DEFICIENCY $1,408,332
Basic Biology I: Helen Blau Immune capabilities of hematopoietic cells derived from human totipotent stem cells $1,408,332
Basic Biology I: Helen Blau The Control of Proliferation, Migration, and Differentiation of Human Pluripotent Stem Cells-Derived Neural Progenitor Cells by MicroRNAs $1,408,332
Basic Biology I: Susan McConnell Mechanism of BCL6-dependent stem cell maintenance in B cell lineage leukemia $1,404,853
Basic Biology I: Julien Sage Identification of molecules that modulate adult neural and brain tumor stem cell biology $1,363,171
Basic Biology II: Garry Nolan Mimicking growth control in regenerative organisms to permit mammalian regeneration $1,343,789
Basic Biology II: Garry Nolan Molecular control of the bidirectional transition between stem cells and skeletal muscles $1,343,789
Basic Biology II: Garry Nolan The role of RNA in regulating de novo DNA methylation in hESC differentiation $1,343,789
SEED Grant: Susan McConnell Derivation and characterization of dopamine neurons from human embryonic stem cells $608,265
SEED Grant: Susan McConnell Comprehensive study of the osteogenic potential of human embryonic stem cells - are they equivalent to liposuctioned fat and bone marrow derived stem cells? $608,265
SEED Grant: Susan McConnell Chromosome instability due to telomere loss in human embryonic stem cells $608,265
SEED Grant: Julien Sage Anesthetic Effects on Neural Stem Cells $498,609
SEED Grant: Julien Sage Engineering Bioactive Hydrogels for Neuronal Differentiation of hESCs $498,609
SEED Grant: Julien Sage NOVEL REAGENTS TO CONTROL STEM CELL DIFFERENTIATION $498,609
SEED Grant: Joanna Wysocka Establishment of human Embryonic Stem Cell Models to Study the Impact of Alzheimer's Disease Mutant Genes on Neuronal Functions $629,952
SEED Grant: Aaron Hsueh Molecular Analysis of microRNAs in Pancreas Development $629,653
SEED Grant: Aaron Hsueh Assessment of the Immune Potential of Human Embryonic Stem Cells $629,653
SEED Grant: Aaron Hsueh Targeted Differentiation of Novel hESC Lines for Bladder Tissue Engineering Applications $629,653
SEED Grant: Susan McConnell Neurogenesis in Alzheimer's Disease: A-beta, Friend or Foe? $608,265
SEED Grant: Susan McConnell A novel approach for pancreatic beta-cell differentiation in vitro and in vivo $608,265
SEED Grant: John Cooke Nanotechnology Differentiation of Human Embryonic Stem Cells (hESCs) $476,995
SEED Grant: John Cooke Molecular Markers of Chondrogenesis $476,995
SEED Grant: John Cooke Developing an Effective Stem Cell Gene Therapy to Treat Human Disease $476,995
SEED Grant: John Cooke DETERMINING THE ROLE OF MITOCHONDRIA IN THE REGULATION OF HUMAN EMBRYONIC STEM CELLS $476,995
SEED Grant: John Cooke Control of embryonic stem cell transcription by TGFb/Smad signaling $476,995
SEED Grant: John Cooke Precursors isolated from human embryonic stem cell culture: potential use for kidney regeneration $476,995
SEED Grant: John Cooke A HUMAN EMBRYONIC STEM CELL MODEL FOR THE DEVELOPMENT OF CD30-POSITIVE HODGKIN LYMPHOMA REED-STERNBERG CELLS (H-RS) $476,995
SEED Grant: John Cooke An Optimal Bioreactor For Production Of Erythrocytes From Human Embryonic Stem Cells $476,995
SEED Grant: Mark Kay Characterization and Modulation of the Natural Antibody-Mediated Immune Response to Human Embryonic Stem Cells $574,737
Basic Biology III: Sean Wu Elucidating Molecular Basis of Hypertrophic Cardiomyopathy with Human Induced Pluripotent Stem Cells $1,264,248
New Faculty Physician Scientist: Alan Cheng Enhancing hair cell regeneration in mouse and human inner ear $3,091,595
Disease Team Research I: Gary Steinberg Embryonic-Derived Neural Stem Cells for Treatment of Motor Sequelae following Sub-cortical Stroke $20,000,000
Basic Biology IV: Michael Cleary Prostaglandin pathway regulation of self-renwal in hematopoietic and leukemia stem cells $1,244,455
Basic Biology IV: Anne Brunet Energy metabolism and aging pathways in human stem cell reprogramming and differentiation $1,414,044
Basic Biology IV: Gerald Crabtree Mechanism and Utility of Direct Neuronal Conversion with a MicroRNA-Chromatin Switch $1,392,426
Basic Biology IV: Ben Barres Phenotyping Human Astrocytes in Health and Disease $0
Early Translational II: Michele Calos Stem Cell Therapy for Duchenne Muscular Dystrophy $2,267,900
Basic Biology IV: Alexander Dunn Role of mechanical signaling in stem cell self-renewal and differentiation $1,064,224
Basic Biology IV: Michelle Monje Stem Cell Mechanisms Governing Discrete Waves of Gliogenesis in the Childhood Brain $1,264,248
Basic Biology IV: Roel Nusse Asymmetric stem cell division oriented by a local self-renewing signal $1,039,058
New Faculty II: Ching-Pin Chang VEGF signaling in adventitial stem cells in vascular physiology and disease $3,008,076
Basic Biology IV: Howard Chang Long noncoding RNAs for pluripotency and cell fate commitment $1,386,627
Transplantation Immunology: Robert Negrin Regulatory T cell induced tolerance to ESC transplantation $1,383,147
Basic Biology III: Michael Clarke USP16 controls stem cell number: implications for Down Syndrome $1,264,032
Basic Biology III: Aaron Hsueh Correlated time-lapse imaging and single cell molecular analysis of human embryo development $1,260,122
Basic Biology III: Joanna Wysocka Enhancer-mediated gene regulation during early human embryonic development $1,425,600
Basic Biology I: Susan McConnell Identification and characterization of human ES-derived DA neuronal subtypes $1,404,853
SEED Grant: Joanna Wysocka Role of Chromatin Modifiers in Regulating Human Embryonic Stem Cell Pluripotency $629,952
SEED Grant: Phillip Yang In Vivo Molecular Magnetic Resonance Imaging of Human Embryonic Stem Cells in Murine Model of Myocardial Infarction $629,952
SEED Grant: Susan McConnell Optimization of guidance response in human embryonic stem cell derived midbrain dopaminergic neurons in development and disease $608,265
SEED Grant: Mark Kay Novel vectors for gene transfer into human ES cells $574,737
SEED Grant: Julien Sage Functions of RB family proteins in human embryonic stem cells $498,609
Comprehensive Grant: Irving Weissman Prospective isolation of hESC-derived hematopoietic and cardiomyocyte stem cells $2,471,386
Comprehensive Grant: Theo Palmer Immunology of neural stem cell fate and function $2,396,000
Comprehensive Grant: Stefan Heller Generation of inner ear sensory cells from human ES cells toward a cure for deafness $2,330,559
Comprehensive Grant: Roel Nusse Guiding the developmental program of human embryonic stem cells by isolated Wnt factors $1,710,817
Comprehensive Grant: Julie Baker Functional Genomic Analysis of Chemically Defined Human Embryonic Stem Cell $2,518,303
Comprehensive Grant: Christopher Zarins Engineering a Cardiovascular Tissue Graft from Human Embryonic Stem Cells $2,454,490
Comprehensive Grant: Renee Reijo Pera Human oocyte development for genetic, pharmacological and reprogramming applications $2,298,411
Early Translational I: Michael Longaker Enhancing healing via Wnt-protein mediated activation of endogenous stem cells $6,464,126
Transplantation Immunology: Christopher Contag Engineering Embryonic Stem Cell Allografts for Operational Tolerance $1,411,588
Transplantation Immunology: Kenneth Weinberg “Engineered immune tolerance by Stem Cell-derived thymic regeneration” $1,289,195
SEED Grant: Joseph Wu In Vivo Imaging of Human Embryonic Stem Cell Derivatives and Tumorigenicity $623,634
SEED Grant: Aaron Hsueh Patient-specific cells with nuclear transfer $629,653
SEED Grant: Kenneth Weinberg Embryonic stem cell-derived thymic epithelial cells $628,793
Basic Biology I: Julien Sage The retinoblastoma (RB) gene family in cellular reprogramming $1,363,171
Basic Biology I: Helen Blau Molecular Mechanisms of Reprogramming towards Pluripotency $1,408,332
Basic Biology II: Steven Artandi Self-renewal and senescence in iPS cells derived from patients with a stem cell disease $931,285
Basic Biology II: Garry Nolan Kinase signaling analysis of iPS cell reprogramming and differentiation $1,343,789
Basic Biology II: Aaron Hsueh Maturation of Human Oocytes for SCNT and Embryonic Stem Cell Derivation $1,309,018
Transplantation Immunology: Judith Shizuru Purified allogeneic hematopoietic stem cells as a platform for tolerance induction $1,233,275
New Cell Lines: Julie Baker Derivation of hESC Lines with Disease Lesions $1,404,725
New Cell Lines: Michele Calos Safe, efficient creation of human induced pluripotent stem cells without the use of retroviruses $1,406,875
New Cell Lines: Michael Longaker Derivation and analysis of pluripotent stem cell lines with inherited TGF-b mediated disorders from donated IVF embryos and reprogrammed adult skin fibroblasts $1,406,636
SEED Grant: Thomas Wandless Reprogramming Differentiated Human Cells to a Pluripotent State $380,005
SEED Grant: John Cooke EC regeneration in cerebrovascular ischemia: role of NO $476,995
SEED Grant: Calvin Kuo Differentiation of Human Embryonic Stem Cells to Intestinal Fates $554,176
SEED Grant: Krishna Shenoy Technology for hESC-Derived Cardiomyocyte Differentiation and Optimization of Graft-Host Integration in Adult Myocardium $572,891
New Cell Lines: Renee Reijo Pera Derivation and comparative analysis of human pluripotent ESCs, iPSCs and SSCs: Convergence to an embryonic phenotype $1,409,441
Shared Labs: Hiromitsu Nakauchi Center for Human Embryonic Stem Cell Research and Education $3,434,600
Disease Team Research I: Alfred Lane iPS Cell-Based Treatment of Dominant Dystrophic Epidermolysis Bullosa $11,039,208
Shared Labs: Renee Reijo Pera Center for Human Embryonic Stem Cell Research and Education $2,439,590
Total:
$235,897,820.00

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© 2013 California Institute for Regenerative Medicine