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University of California, San Francisco

Total Awards:

50

ICOC Committed funds:

135 623 952

Major Facility Name:

Ray and Dagmar Dolby Regeneration Medicine Building

Awards to the Institution

			Funding
Basic Biology III:	Harold Bernstein	Phenotypic Analysis of Human ES Cell-Derived Muscle Stem Cells	$1,381,296
Basic Biology III:	John Murnane	Genomic instability during culturing of human embryonic stem cells	$1,074,355
New Faculty II:	Robert Blelloch	Mechanisms of small RNA regulation in early embryonic development	$3,204,897
New Faculty II:	Holger Willenbring	Molecular dissection of adult liver regeneration to guide the generation of hepatocytes from pluripotent stem cells	$3,207,510
New Faculty II:	Jeremy Reiter	High throughput modeling of human neurodegenerative diseases in embryonic stem cells	$2,259,092
New Faculty II:	Ophir Klein	Laying the groundwork for building a tooth: analysis of dental epithelial stem cells	$3,250,251
New Faculty II:	Emmanuelle Passegue	Mechanisms Underlying the Responses of Normal and Cancer Stem Cells to Environmental and Therapeutic Insults	$2,274,368
New Cell Lines:	Susan Fisher	Optimization of Human Embryonic Stem Cell Derivation Techniques and Production/Distribution of GMP-Grade Lines	$1,383,419
New Cell Lines:	Long-cheng Li	Induction of pluripotent stem cells by small RNA-guided transcriptional activation	$1,375,144
New Cell Lines:	Miguel Ramalho-Santos	Somatic cell age and memory in the generation of iPS cells	$1,307,201
Tools and Technologies II:	Daniel Lim	Development and preclinical testing of new devices for cell transplantation to the brain.	$1,831,723
Early Translational II:	Arturo Alvarez-Buylla	Inhibitory Nerve Cell Precursors: Dosing, Safety and Efficacy	$1,752,058
Basic Biology II:	John Rubenstein	MGE Enhancers to Select for Interneuron Precursors Produced from Human ES Cells	$1,387,800
Disease Team Research I:	Mitchel Berger	Stem Cell-Mediated Oncocidal Gene Therapy of Glioblastoma (GBM)	$19,162,435
Research Training II:	Susan Fisher	Training Program in Stem Cell Research	$7,946,605
Shared Labs:	Linda Giudice	Shared Research and Teaching Laboratory: a Non-Federal Human Embryonic Stem Cell Resource for the Bay Area Community	$5,546,877
Comprehensive Grant:	Andrew Leavitt	Understanding hESC-based Hematopoiesis for Therapeutic Benefit	$2,566,702
Comprehensive Grant:	Randall Lee	Embryonic Stem Cell-Derived Therapies Targeting Cardiac Ischemic Disease	$2,524,617
Comprehensive Grant:	Harold Bernstein	Modeling Myocardial Therapy with Human Embryonic Stem Cells	$2,229,140
Comprehensive Grant:	Samuel Pleasure	Human stem cell derived oligodendrocytes for treatment of stroke and MS	$2,566,701
Comprehensive Grant:	Arnold Kriegstein	Derivation of Inhibitory Nerve Cells from Human Embryonic Stem Cells	$2,507,223
Comprehensive Grant:	Susan Fisher	Constructing a fate map of the human embryo	$2,532,388
SEED Grant:	Miguel Ramalho-Santos	Transcriptional Regulation of Human Embryonic Stem Cells	$618,901
SEED Grant:	Thea Tlsty	Role of the tumor suppressor gene, p16INK4a, in regulating stem cell phenotypes in embryonic stem cells and human epithelial cells.	$639,150
SEED Grant:	Valerie Weaver	Force, Dimensionality and Stem Cell Fate	$561,082
SEED Grant:	Linda Giudice	Human Embryonic Stem Cell Differentiation to Trophoblast: Basic Biology and Clinical Translation to Improve Human Fertility	$640,399
SEED Grant:	Robert Blelloch	MicroRNA Regulation of Human Embryonic Stem Cell Self-Renewal and Differentiation	$631,831
SEED Grant:	Su Guo	Identifying small molecules that stimulate the differentiation of hESCs into dopamine-producing neurons	$564,309
SEED Grant:	Holger Willenbring	Induction of pluripotency in fibroblasts by fusion with enucleated human embryonic stem cell syncytia	$342,962
SEED Grant:	Didier Stainier	Endodermal differentiation of human ES cells	$635,242
			Total: $77,905,678.00

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© 2013 California Institute for Regenerative Medicine