Buck Institute for Age Research
ICOC Committed funds:
Awards as PI
|Early Translational II||Banking transplant ready dopaminergic neurons using a scalable process||$6,016,624|
|Shared Labs||CIRM Shared Research Laboratory for Stem Cells and Aging||$5,893,682|
|Disease Team Planning||Develop a cell replacement therapy for Parkinson's disease using human embryonic stem cells||$55,000|
A targeted neuroglial reporter line generated by homologous recombination in human embryonic stem cells.
Xeno-free defined conditions for culture of human embryonic stem cells, neural stem cells and dopaminergic neurons derived from them.
Identification by automated screening of a small molecule that selectively eliminates neural stem cells derived from hESCs but not dopamine neurons.
Efficient generation of functional dopaminergic neurons from human induced pluripotent stem cells under defined conditions.