Application Number Funding Recommendation Title Score RN1-00577 Recommended---- Genetic Encoding Novel Amino Acids in Embryonic Stem Cells for Molecular Understanding of Differentiation to Dopamine Neurons 96 RN1-00561 Recommended---- Combinatorial Chemistry Approaches to Develop LIgands against Leukemia Stem Cells 94 RN1-00579 Recommended---- Trithorax and Polycomb methyltransferase complexes in cell fate determination. 92 RN1-00566 Recommended---- A Novel Engineered Niche to Explore the Vasculogenic Potential of Embryonic Stem Cells 90 RN1-00584 Recommended---- Generating pluripotent cell lines from neurons. 90 RN1-00527 Recommended---- Molecular mechanisms involved in adult neural stem cell maintenance 90 RN1-00563 Not recommended---- Mechanisms Underlying the Responses of Normal and Cancer Stem Cells to Environmental and Therapeutic Insults 88 RN1-00575 Recommended---- Genetic dissection of mesodermal commitment to the hematopoietic fates. 88 RN1-00548 Not recommended---- Laying the foundation for building a tooth: analysis of mammalian dental epithelial stem cells. 85 RN1-00529 Recommended---- Noncoding RNAs in Cell Fate Determination 85 RN1-00582 Not recommended---- The molecular basis underlying adult neurogenesis during regeneration and tissue renewal 83 RN1-00532 Recommended---- Identification of hESC-mediated molecular mechanism that positively regulates the regenerative capacity of post-natal tissues 83 RN1-00564 Recommended---- In vitro reprogramming of mouse and human somatic cells to an embryonic state 82 RN1-00525 Recommended---- Skeletal muscle development from hESC and its in vivo applications in animal models of muscular dystrophy 80 RN1-00544-A Recommended---- Characterization of mechanisms regulating de-differentiation and the re-acquisition of stem cell identity 77 RN1-00544-B Recommended---- Characterization of mechanisms regulating de-differentiation and the re-acquisition of stem cell identity 77 RN1-00533 Not recommended---- Skeletogenic Neural Crest Cells in Embryonic Development and Adult Regeneration of the Jaw 77 RN1-00530 Recommended---- Molecular mechanisms of neural stem cell differentiation in the developing brain 77 RN1-00567 Not recommended---- High throughput modeling of human neurodegenerative diseases in embryonic stem cells 75 RN1-00543 Not recommended---- Derivation and Characterization of Myeloproliferative Disorder Stem Cells From Human ES Cells 75 RN1-00557 Recommended---- Mechanisms of Hematopoietic stem cell Specification and Self-Renewal 73 RN1-00562-1.2 Recommended---- Transcriptional Regulation of Cardiac Pacemaker Cell Progenitors 72 RN1-00562 Recommended---- Transcriptional Regulation of Cardiac Pacemaker Cell Progenitors 72 RN1-00580 Not recommended---- Mechanisms underlying the diverse functions of STAT3 in pluripotent stem cell fate regulation 71 RN1-00572 Recommended---- Oral and Craniofacial Reconstruction Using Mesenchymal Stem Cells 69 RN1-00540 Recommended if funds allow---- Mechanisms of Stem Cell Fate Decisions 65 RN1-00536-B Recommended if funds allow---- Reprogramming of human somatic cells back to pluripotent embryonic stem cells 65 RN1-00536-A Recommended if funds allow---- Reprogramming of human somatic cells back to pluripotent embryonic stem cells 65 RN1-00581 Not recommended---- Regulation of Adult Stem Cell Proliferation and Number 63 RN1-00569 Not recommended---- Stem Cells for Immune System Regeneration to Fight Cancer 62 RN1-00535 Recommended if funds allow---- Bioengineering technology for fast optical control of differentiation and function in stem cells and stem cell progeny 61 RN1-00553 Not recommended---- Mechanisms of NANOG Function in hESC 61 RN1-00550 Recommended---- Epigenetics in cancer stem cell initiation and clinical outcome prediction 61 RN1-00549 Not recommended---- Epigenetic determinants of normal and tumor stem cell biology -- RN1-00554 Recommended if funds allow---- Enhancing Survival of Embryonic Stem Cell-Derived Grafts by Induction of Immunological Tolerance -- RN1-00526 Not recommended---- Reprogramming the Cancer Genome -- RN1-00545 Not recommended---- Neural progenitors and Alzheimer's disease -- RN1-00560 Not recommended---- Identification and functional analysis of stem cells in acute lymphoblastic leukemia -- RN1-00539 Not recommended---- Directed Stem Cell Recruitment into the CNS in Response to Coxsackievirus Infection -- RN1-00547 Not recommended---- Stem cell regeneration of neural circuits in murine Huntington's disease models -- RN1-00574 Not recommended---- Analysis of MELK Function In Vivo in CNS Neural Progenitors And in Brain Tumors -- RN1-00573 Not recommended---- Immune Regulation of Retinal Stem Cell Migration and Survival -- RN1-00538-A Recommended if funds allow---- ES-Derived Cells for the Treatment of Alzheimer's Disease -- RN1-00538-B Recommended if funds allow---- ES-Derived Cells for the Treatment of Alzheimer's Disease -- RN1-00542 Not recommended---- Role of Apolipoprotein E in Hippocampal Neurogenesis and Its Therapeutic Potential in Alzheimer's Disease -- RN1-00583 Not recommended---- Developing a transplantation therapy for Parkinson's disease using hESC-derived dopaminergic neurons. -- RN1-00546 Not recommended---- The role of hyaluronan in regulation of differentiation of hESCs in hematopoietic lineage -- RN1-00537 Not recommended---- Investigation of the Potential of Mouse Embryonic Stem Cells to Develop into Neuroendocrine Cells in Vitro -- RN1-00578 Not recommended---- Tumor Neovascularization by a Non-angiogenic Mechanism: Plasticity-based Contributions by Brain Stem Cells. -- RN1-00568 Not recommended---- Designing a microenvironment niche for hepatic differentiation of hESCs -- RN1-00534 Not recommended---- Interactions Between Stem Cells and Cartilage in Health and Disease -- RN1-00558 Not recommended---- Using Stem Cells to Make, Study, and Sort Useful Forebrain Cells -- RN1-00531 Not recommended---- Inducing human embryonic stem cell differentiation into cardiomyocytes using extracellular matrix cues -- RN1-00559 Not recommended---- Isolation of Fetal Hepatic Stem Cells for In Utero Transplantation -- RN1-00570 Not recommended---- Investigation of the molecular pathways that integrate self-renewal and cell structure in embryonic stem cells. -- RN1-00528 Not recommended---- Characterization of Immune Responses in Human Embryonic Stem Cells -- RN1-00552 Not recommended---- Replenishing Dysfunctional Testes with Stem Cells -- RN1-00555 Not recommended---- Building Cardiac Tissue from Stem Cells -- RN1-00571 Not recommended---- A novel and generalizable organotypic slice model to evaluate stem cell potential for targeting pediatric brain tumors -- RN1-00551 Not recommended---- Engraftment and Differentiation of Adult Human Stem Cells in Embryonic Eye -- RN1-00565 Not recommended---- Stem Cell Differentiation in Cytopenias -- RN1-00576 Not recommended---- A novel system for understanding the effects of natural genetic variation and epigenetics of stem cells. -- RN1-00541 Not recommended---- Induction of tolerance in NOD mice using genetically engineered human adipose-derived mesenchymal stem cells --