CIRM Funded Clinical Trials

Induction of Tolerance to Combined Kidney and Hematopoietic Progenitor Cell Transplants from HLA Haplotype Matched Living Donors


Samuel Strober
Disease Area: 
Investigator:
CIRM Grant:
Award Value:
$6,653,266
Trial Sponsor:
Stanford University
Trial Stage: 
Phase 1
Trial Status: 
Recruiting
Targeted Enrollment:
15
ClinicalTrials.gov ID:
Details: 

Stanford scientists are working with kidney transplant patients to see if injecting blood stem cells and T cells (which play an important role in the immune system) from the kidney donor into the kidney recipient can enable the recipient to bypass the need for a life-long dependence on immunosuppressant drugs which have numerous negative side effects.

Design: 

Open label, single arm study.

Goal: 

Primary: Safety. Secondary: Preliminary efficacy.

Updates: 

Enrolling. Opening additional sites.