Basic Biology II

Basic Biology Awards II

The CIRM Basic Biology Awards II program will fund research grants to investigate basic mechanisms underlying stem cell biology, cellular plasticity, and cellular differentiation.  Studies supported by these awards will form the foundation for future translational and clinical advances, enabling the realization of the full potential of human stem cells and reprogrammed cells for therapies and as tools for biomedical innovation.

This RFA is the second of a two-part Basic Biology Awards Initiative.  Applicants who submitted a PreApp for the Basic Biology Awards I RFA are not eligible to submit a PreApp for the Basic Biology Awards II RFA.  It is important to note that CIRM plans to re-issue an RFA covering Basic Biology in 2010. Applicants whose proposals are deferred and who are not invited to submit a full application in 2009 have the opportunity to reapply in the 2010 cycle of Basic Biology Awards.

Our collaborative funding partner, the Japanese Science and Technology Agency (JST) will participate in this RFA.

Please see the RFA for full details.

Note: Appendix A describes additional requirements and procedures for applicants whose proposals include a Japanese collaborator to be funded by the Japanese Science and Technology Agency (JST). The JST Pre-Application Form should be completed only by Japanese collaborators and should be submitted directly to the JST. California applicants with or without collaborative projects must apply as described below.

Preliminary Application Instructions and Forms

Submission of an application for the CIRM Basic Biology Awards II involves a two step process in which an applicant first submits a Preliminary Application (Pre-Application; PreApp) and subsequently submits a Full Application only if invited to do so by CIRM.  PreApps will be evaluated by scientific specialists from outside California who are experts in specific areas of research described in the PreApp and by CIRM scientific staff, based on scientific review criteria described in section VI of the RFA.  Applicants whose projects are judged as most promising, competitive, and responsive to the RFA will be invited to submit a Full Application.  Applicants who are not invited to submit a Full Application will be deferred; these applicants may reapply when the Basic Biology RFA is repeated in 2010.

Each applicant must submit a Pre-Application using the PreApp Form for Basic Biology Awards II. In addition to the PreApp form, all applicants must submit a Related Business Entities Disclosure Form. Each eligible applicant may submit only a single PreApp for this RFA.  Applicants who submitted a PreApp for the Basic Biology Awards I RFA (RFA 08-07) are not eligible to apply for this RFA.


The completed PreApp form (less the Official signature) and the Related Business Entities Disclosure Form must be sent as interactive pdf documents (the original document format; documents must not be "flattened" or converted to another format) as distinct email attachments to BasicBiologyPreApp@CIRM.ca.gov and must be received by CIRM no later than 5:00 pm (PDT) on September 3, 2009.  Additionally, a hard copy of the cover (first) page of the PreApp, signed by an institutional official authorized to sign on behalf of the applicant's organization, must be received by CIRM no later than 5:00 pm (PDT), on September 3, 2009.  This signed cover page must be sent to:

Basic Biology II PreApp
California Institute for Regenerative Medicine
210 King Street
San Francisco, CA 94107

It is the applicant's responsibility to meet this deadline; no exceptions will be made.

You will need a fully functional copy of Adobe Acrobat version 8 or 9 (Standard or Professional) to complete, print, and save the PreApp and Related Business Entities Disclosure Forms.  We recommend using Adobe Acrobat version 8.1 (or the latest version). Using Adobe Acrobat Reader will not permit you to save information that is entered in the form.

Full Application Instructions and Forms

Full Applications will only be accepted from applicants who 1) submitted a PreApp and 2) are invited by CIRM to submit a Full Application.

The Full Application consists of four parts: Part A: Application Information Form, Part B: Basic Biology Award Research Proposal, Part C: Biographical Sketches for Key Personnel, and Part D: Related Business Entities Disclosure Form.  All four parts of the full application for CIRM Basic Biology Awards II must be submitted together and received by CIRM no later than 5:00 pm (PST) on December 8, 2009, in both electronic form and in hard copy (a signed original and five copies). It is the applicant's responsibility to meet this deadline; no exceptions will be made.

Send electronic copies of all parts of the application as attachments in a single email to BasicBiologyAwards@cirm.ca.gov. In addition to the electronic submission, candidates must submit an original copy of the application (consisting of Parts A-D) signed by both the applicant and the institution's Authorized Organizational Official (AOO), plus 5 copies of the full application (preferably double-sided) to:

Basic Biology Awards II Application
California Institute for Regenerative Medicine
210 King Street
San Francisco, CA 94107

You will need a fully functional copy of Adobe Acrobat version 8 or 9 (Standard or Professional) to complete, print, and save Parts A and D of the Full Application.  We recommend using Adobe Acrobat version 8.1 (or the latest version). Using Adobe Acrobat Reader will not permit you to save information that is entered in the form.

 
Schedule of Deadlines and Reviews Date
Pre-Applications due 5:00 PM (PDT), September 3, 2009
Invitations for full applications sent out by CIRM Last week of October 2009
Full applications due 5:00 PM (PST), December 8, 2009
Review of full applications by Grants Working Group (GWG) February, 2010
Review and Approval by ICOC April, 2010
Earliest Funding of Awards Summer, 2010

No exceptions will be made to the indicated deadlines.

 

ICOC approval: 
Apr 29, 2010

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