CIRM-funded clinical trials

Clinical trials based on CIRM funding

Before a new therapy is widely available in doctors offices, it goes through several rounds of carefully regulated testing in people. These happen in three stages:

  1. Phase 1 trials include a very small number of people and are primarily intended to test whether the proposed therapy is safe.
  2. Phase 2 trials include slightly more people and are intended to verify that the therapy is safe, and to start looking into whether it is effective at treating the disease or condition.
  3. Phase 3 trials include large numbers of people and are intended to test whether the therapy treats the disease or condition.

All clinical trials carried out in the United States are required to be listed on the clinicaltrials.gov website. Those trials being carried out in other countries won't always have additional trial details available through that site.

Trials directly funded by CIRM

These clinical trials are being directly funded by grants from CIRM.

Grantee Disease Grant Trial details
Geron Spinal cord injury Targeted Clinical Development Phase 1
NCT01217008
CLOSED
Capricor Heart disease Disease Team Phase 1/2 NCT01458405
Calimmune HIV/AIDS Disease Team Phase 1/2 NCT01734850
UC Davis Huntington's disease Disease Team Observational
NCT01937923
UCLA Solid tumors Disease Team Phase 1
UCSD Leukemia Disease Team Phase 1
UCLA Sickle cell disease Disease Team Phase 1 (not yet enrolling)
Stanford Solid tumors Disease Team Phase 1

Trials based on earlier research grants

These clinical trials are based on discoveries made by our grantees when they were carrying out CIRM-funded research.

Grantees Trial sponsor Disease Supporting Grant Trial details
Catriona Jamieson TargeGen/Sanofi Myelofibrosis Training
SEED

Phase 1
NCT00631462

Phase 1/2
NCT00724334

Catriona Jamieson Sanofi Polycythemia vera Training
SEED
New Faculty
 

Phase 2
NCT01420770

Phase 2
NCT01420783

Phase 2
NCT01523171

Phase 3
NCT01437787

CLOSED

Dennis Carson
Catriona Jamieson
John Dick
Pfizer Leukemia Disease Team

Phase 1
NCT00953758

Phase 1/2
NCT01546038

Joel Gottesfeld Repligen, Corp Ataxia Basic Biology Phase 1 Italy

Antoni Ribas
Zoran Galic

Jonsson Comprehensive Cancer Center Metastatic melanoma

SEED
New Faculty

Phase 2 NCT00910650

Katja Piltti
Aileen Anderson

Stem Cells, Inc Spinal cord injury Training Phase 1/2
NCT01321333

 

© 2013 California Institute for Regenerative Medicine