Scripps Research Institute
ICOC Committed funds:
Awards as PI
|Shared Labs||Center for hESC Research||$5,216,885|
|Tools and Technologies I||The Stem Cell Matrix: a map of the molecular pathways that define pluripotent cells||$1,141,124|
|Early Translational I||Ensuring the safety of cell therapy: a quality control pipeline for cell purification and validation||$6,292,290|
|Transplantation Immunology||Thymus based tolerance to stem cell therapies||$1,269,844|
Awards as Co-PI
Friedreich's ataxia induced pluripotent stem cells model intergenerational GAATTC triplet repeat instability.
Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture.
Recurrent variations in DNA methylation in human pluripotent stem cells and their differentiated derivatives.
Evidence That Gene Activation and Silencing during Stem Cell Differentiation Requires a Transcriptionally Paused Intermediate State.