Research and Development
Advancing Cutting Edge Stem Cell and Gene Therapy Research
CIRM is a catalyst for discovery, facilitating cutting edge scientific endeavors in cell and gene therapy to advance regenerative medicine in California and beyond.
As a world leader in this field, CIRM prioritizes three key aspects of research and development:
Photo Credit: Angiocrine Bioscience
Development of Cell and Gene Therapies
CIRM is committed to advancing cell and gene therapies from discovery stage to market. Through CIRM’s Translation program, clinical trial funding model, and clinical infrastructure, we emphasize not only patient access but also the consistent scaling of manufacturing processes to meet regulatory quality requirements and clinical demand.
Advancements in Regenerative Medicine Technologies
CIRM has supported discovery and translation research to improve the development of technologies such as cell reprogramming, gene editing, therapy delivery systems, and others, ensuring continuous advancements in the field.
Collaborative Networks for Discovery Research
By supporting initiatives which advance our understanding of complex diseases, CIRM aims to translate scientific discoveries into patient benefits. CIRM is fostering collaborative networks to unite multidisciplinary teams, enhancing our understanding of disease mechanisms, and leading to the discovery of novel targets and biomarkers that will push the boundaries in the treatment development for these diseases. In line with Proposition 14’s emphasis, CIRM has prioritized the development of treatments for neurological conditions.
Learn about the infrastructure that supports our R&D efforts.
Our Research and Development Programs
CIRM’s Research and Development (R&D) programs lay the foundation for groundbreaking advancements in regenerative medicine, starting with early investment in innovative scientific research within academic and laboratory settings. These discovery research efforts have not only driven scientific innovation but also seeded a thriving regenerative medicine industry, contributing significantly to California’s robust research ecosystem.
Building on this foundation, CIRM supports the entire developmental pipeline, including pre-clinical research, clinical research, and clinical trials, to turn promising ideas into real-world treatments. Each stage is a critical pillar in advancing CIRM’s mission to accelerate stem cell and gene therapy research and deliver transformative therapies to patients.
Discovery Research
CIRM invest in early-stage basic, or Discovery, research that advances our understanding of how stem cells and genes work and explores new and groundbreaking stem cell and gene therapy treatments and technologies.
Translational Research
CIRM drives the best research to advance to the next level by supporting the foundational quality work for entry into the clinical trial stages.
Clinical Research
CIRM is building a world-class therapeutics portfolio and supporting each project with a Clinical Advisory Panel that include patient advocates along with subject matter experts and other resources to enhance its chances of success into and through clinical trials.
