Antiviral cellular therapy for enhancing T-cell reconstitution before or after hematopoietic stem cell transplantation (ACES): a two-arm, open label phase II interventional trial of pediatric patients with risk factor assessment. |
2024 |
Nat Commun |
Custom-engineered hydrogels for delivery of human iPSC-derived neurons into the injured cervical spinal cord. |
2024 |
Biomaterials |
Disease modeling and pharmacological rescue of autosomal dominant retinitis pigmentosa associated with RHO copy number variation. |
2024 |
Elife |
Early-life stress triggers long-lasting organismal resilience and longevity via tetraspanin. |
2024 |
Sci Adv |
Generation of ‘semi-guided’ cortical organoids with complex neural oscillations. |
2024 |
Nat Protoc |
Generation of antigen-specific mature T cells from RAG1(-/-)RAG2(-/-)B2M(-/-) stem cells by engineering their microenvironment. |
2024 |
Nat Biomed Eng |
Harnessing Biomaterials to Amplify Immunity in Aged Mice through T Memory Stem Cells. |
2024 |
ACS Nano |
Locoregional delivery of IL-13Ralpha2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial. |
2024 |
Nat Med |
Non-invasive prenatal testing of beta-hemoglobinopathies using next generation sequencing, in-silico sequence size selection, and haplotyping. |
2024 |
Croat Med J |
Respiratory exposure to agricultural dust extract promotes increased intestinal Tnfalpha expression, gut barrier dysfunction, and endotoxemia in mice. |
2024 |
Am J Physiol Gastrointest Liver Physiol |
Secondary bone marrow graft loss after third-party virus-specific T cell infusion: Case report of a rare complication. |
2024 |
Nat Commun |
Small molecule inhibition of RNA binding proteins in haematologic cancer. |
2024 |
RNA Biol |
Stem cell-derived CAR T cells show greater persistence, trafficking, and viral control compared to ex vivo transduced CAR T cells. |
2024 |
Mol Ther |
Targeting IGF2BP3 enhances antileukemic effects of menin-MLL inhibition in MLL-AF4 leukemia. |
2024 |
Blood Adv |
Therapeutic potential of human microglia transplantation in a chimeric model of CSF1R-related leukoencephalopathy. |
2024 |
Neuron |
[Cystinosis: From the gene identification to the first gene therapy clinical trial]. |
2023 |
Med Sci (Paris) |
A bio-instructive parylene-based conformal coating suppresses thrombosis and intimal hyperplasia of implantable vascular devices. |
2023 |
Bioact Mater |
A bioactive material with dual integrin-targeting ligands regulates specific endogenous cell adhesion and promotes vascularized bone regeneration in adult and fetal bone defects. |
2023 |
Bioact Mater |
A covalent inhibitor of the YAP-TEAD transcriptional complex identified by high-throughput screening. |
2023 |
RSC Chem Biol |
A Roadmap for a Consensus Human Skin Cell Atlas and Single-Cell Data Standardization. |
2023 |
J Invest Dermatol |
A scalable, GMP-compatible, autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa. |
2023 |
bioRxiv |
A spatially resolved single-cell genomic atlas of the adult human breast. |
2023 |
Nature |
Abrupt perturbation and delayed recovery of the vaginal ecosystem following childbirth. |
2023 |
Nat Commun |
Allele-specific expression reveals genetic drivers of tissue regeneration in mice. |
2023 |
Cell Stem Cell |
An altered extracellular matrix-integrin interface contributes to Huntington’s disease-associated CNS dysfunction in glial and vascular cells. |
2023 |
Hum Mol Genet |
An Inexpensive 3D Printed Mouse Model of Successful, Complication-free Long Bone Distraction Osteogenesis. |
2023 |
Plast Reconstr Surg Glob Open |
An iPSC-derived astrocyte model of fragile X syndrome exhibits dysregulated cholesterol homeostasis. |
2023 |
Commun Biol |
Antigen-dependent IL-12 signaling in CAR T cells promotes regional to systemic disease targeting. |
2023 |
Nat Commun |
Antiretrovirals to CCR5 CRISPR/Cas9 gene editing – A paradigm shift chasing an HIV cure. |
2023 |
Clin Immunol |
Assaying Chemical Long-Term Potentiation in Human iPSC-Derived Neuronal Networks. |
2023 |
Methods Mol Biol |
Attenuating Chronic Fibrosis: Decreasing Foreign Body Response with Acellular Dermal Matrix. |
2023 |
Tissue Eng Part B Rev |
Automated 384-well SYBR Green Expression Array for Optimization of Human Induced Pluripotent Stem Cell Differentiation. |
2023 |
Bio Protoc |
Biodegradable nanoparticles targeting circulating immune cells reduce central and peripheral sensitization to alleviate neuropathic pain following spinal cord injury. |
2023 |
Pain |
Bridging the gap with bacterial art. |
2023 |
FEMS Microbiol Lett |
Broadly neutralizing antibodies targeting HIV: Progress and challenges. |
2023 |
Clin Immunol |
CD203c is expressed by human fetal hepatoblasts and distinguishes subsets of hepatoblastoma. |
2023 |
Front Oncol |
Cellular Therapy for Children with Central Nervous System Tumors: Mining and Mapping the Correlative Data. |
2023 |
Curr Oncol Rep |
Combination of Distinct Vascular Stem/Progenitor Cells for Neovascularization and Ischemic Rescue. |
2023 |
Arterioscler Thromb Vasc Biol |
Comparative analysis between single-cell RNA-seq and single-molecule RNA FISH indicates that the pyrimidine nucleobase idoxuridine (IdU) globally amplifies transcriptional noise. |
2023 |
bioRxiv |
Complex urban atmosphere alters alveolar stem cells niche properties and drives lung fibrosis. |
2023 |
Am J Physiol Lung Cell Mol Physiol |
Conductive electrospun polymer improves stem cell-derived cardiomyocyte function and maturation. |
2023 |
Biomaterials |
Context matters: hPSC-derived microglia thrive in a humanized brain environment in vivo. |
2023 |
Cell Stem Cell |
Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation. |
2023 |
Elife |
Craniofacial developmental biology in the single-cell era. |
2023 |
Development |
CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons. |
2023 |
Nat Commun |
Dermomyotome-derived endothelial cells migrate to the dorsal aorta to support hematopoietic stem cell emergence. |
2023 |
Elife |
Developing a human iPSC-derived three-dimensional myelin spheroid platform for modeling myelin diseases. |
2023 |
iScience |
Developing Hypoimmunogenic Human iPSC-Derived Oligodendrocyte Progenitor Cells as an Off-The-Shelf Cell Therapy for Myelin Disorders. |
2023 |
Adv Sci (Weinh) |
DNA Methylation Dynamics During Esophageal Epithelial Regeneration Following Repair with Acellular Silk Fibroin Grafts in Rat. |
2023 |
Adv Biol (Weinh) |
Efficient manufacturing and engraftment of CCR5 gene-edited HSPCs following busulfan conditioning in nonhuman primates. |
2023 |
Mol Ther Methods Clin Dev |