Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
A Panoramic View of Cell Population Dynamics in Mammalian Aging. 2024 bioRxiv
A therapy for suppressing canonical and noncanonical SARS-CoV-2 viral entry and an intrinsic intrapulmonary inflammatory response. 2024 Proc Natl Acad Sci U S A
AMPK Drives both Glycolytic and Oxidative Metabolism in Murine and Human T Cells During Graft-versus-host Disease. 2024 Blood Adv
An age-progressive platelet differentiation path from hematopoietic stem cells causes exacerbated thrombosis. 2024 Cell
An Endothelial Cell Is Not Simply an Endothelial Cell. 2024 Stem Cells Dev
Antiviral cellular therapy for enhancing T-cell reconstitution before or after hematopoietic stem cell transplantation (ACES): a two-arm, open label phase II interventional trial of pediatric patients with risk factor assessment. 2024 Nat Commun
CAR-T cell therapy targeting surface expression of TYRP1 to treat cutaneous and rare melanoma subtypes. 2024 Nat Commun
Comparing fabrication techniques for engineered cardiac tissue. 2024 J Biomed Mater Res A
Custom-engineered hydrogels for delivery of human iPSC-derived neurons into the injured cervical spinal cord. 2024 Biomaterials
Disease modeling and pharmacological rescue of autosomal dominant retinitis pigmentosa associated with RHO copy number variation. 2024 Elife
Early-life stress triggers long-lasting organismal resilience and longevity via tetraspanin. 2024 Sci Adv
Engineering allorejection-resistant CAR-NKT cells from hematopoietic stem cells for off-the-shelf cancer immunotherapy. 2024 Mol Ther
Fatty acid oxidation in immune function. 2024 Front Immunol
Generation of ‘semi-guided’ cortical organoids with complex neural oscillations. 2024 Nat Protoc
Generation of allogeneic CAR-NKT cells from hematopoietic stem and progenitor cells using a clinically guided culture method. 2024 Nat Biotechnol
Generation of antigen-specific mature T cells from RAG1(-/-)RAG2(-/-)B2M(-/-) stem cells by engineering their microenvironment. 2024 Nat Biomed Eng
Harnessing Biomaterials to Amplify Immunity in Aged Mice through T Memory Stem Cells. 2024 ACS Nano
Locoregional delivery of IL-13Ralpha2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial. 2024 Nat Med
Multi-lineage heart-chip models drug cardiotoxicity and enhances maturation of human stem cell-derived cardiovascular cells. 2024 Lab Chip
Non-invasive prenatal testing of beta-hemoglobinopathies using next generation sequencing, in-silico sequence size selection, and haplotyping. 2024 Croat Med J
Overexpression of AMPKgamma2 increases AMPK signaling to augment human T cell metabolism and function. 2024 J Biol Chem
Respiratory exposure to agricultural dust extract promotes increased intestinal Tnfalpha expression, gut barrier dysfunction, and endotoxemia in mice. 2024 Am J Physiol Gastrointest Liver Physiol
Secondary bone marrow graft loss after third-party virus-specific T cell infusion: Case report of a rare complication. 2024 Nat Commun
Small molecule inhibition of RNA binding proteins in haematologic cancer. 2024 RNA Biol
Stem cell-derived CAR T cells show greater persistence, trafficking, and viral control compared to ex vivo transduced CAR T cells. 2024 Mol Ther
Targeting IGF2BP3 enhances antileukemic effects of menin-MLL inhibition in MLL-AF4 leukemia. 2024 Blood Adv
The Benefits of Stem Cell Biology and Tissue Engineering in Low-Earth Orbit. 2024 Stem Cells Dev
The Importance, Challenges, and Possible Solutions for Sharing Proteomics Data While Safeguarding Individuals’ Privacy. 2024 Mol Cell Proteomics
Therapeutic potential of human microglia transplantation in a chimeric model of CSF1R-related leukoencephalopathy. 2024 Neuron
Updated single cell reference atlas for the starlet anemone Nematostella vectensis. 2024 Front Zool
[Cystinosis: From the gene identification to the first gene therapy clinical trial]. 2023 Med Sci (Paris)
A bio-instructive parylene-based conformal coating suppresses thrombosis and intimal hyperplasia of implantable vascular devices. 2023 Bioact Mater
A bioactive material with dual integrin-targeting ligands regulates specific endogenous cell adhesion and promotes vascularized bone regeneration in adult and fetal bone defects. 2023 Bioact Mater
A covalent inhibitor of the YAP-TEAD transcriptional complex identified by high-throughput screening. 2023 RSC Chem Biol
A Roadmap for a Consensus Human Skin Cell Atlas and Single-Cell Data Standardization. 2023 J Invest Dermatol
A scalable, GMP-compatible, autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa. 2023 bioRxiv
A spatially resolved single-cell genomic atlas of the adult human breast. 2023 Nature
Abrupt perturbation and delayed recovery of the vaginal ecosystem following childbirth. 2023 Nat Commun
Advancing cell-based cancer immunotherapy through stem cell engineering. 2023 Cell Stem Cell
Allele-specific expression reveals genetic drivers of tissue regeneration in mice. 2023 Cell Stem Cell
An altered extracellular matrix-integrin interface contributes to Huntington’s disease-associated CNS dysfunction in glial and vascular cells. 2023 Hum Mol Genet
An Inexpensive 3D Printed Mouse Model of Successful, Complication-free Long Bone Distraction Osteogenesis. 2023 Plast Reconstr Surg Glob Open
An iPSC-derived astrocyte model of fragile X syndrome exhibits dysregulated cholesterol homeostasis. 2023 Commun Biol
Antigen-dependent IL-12 signaling in CAR T cells promotes regional to systemic disease targeting. 2023 Nat Commun
Antiretrovirals to CCR5 CRISPR/Cas9 gene editing – A paradigm shift chasing an HIV cure. 2023 Clin Immunol
Assaying Chemical Long-Term Potentiation in Human iPSC-Derived Neuronal Networks. 2023 Methods Mol Biol
Attenuating Chronic Fibrosis: Decreasing Foreign Body Response with Acellular Dermal Matrix. 2023 Tissue Eng Part B Rev
Automated 384-well SYBR Green Expression Array for Optimization of Human Induced Pluripotent Stem Cell Differentiation. 2023 Bio Protoc
Biodegradable nanoparticles targeting circulating immune cells reduce central and peripheral sensitization to alleviate neuropathic pain following spinal cord injury. 2023 Pain
Bridging the gap with bacterial art. 2023 FEMS Microbiol Lett
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