| A strategic road map to filing a Biologics License Application for a pluripotent stem cell derived
therapeutic product |
2019 |
International Alliance for Biological Standardization |
| Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy. |
2019 |
Nature |
| Allosteric Inhibition of Ubiquitin-like Modifications by a Class of Inhibitor of SUMO-Activating Enzyme. |
2019 |
Cell Chem Biol |
| An Improved Two-Step Protocol for Trophoblast Differentiation of Human Pluripotent Stem Cells. |
2019 |
Curr Protoc Stem Cell Biol |
| An ultrasensitive test for profiling circulating tumor DNA using integrated comprehensive droplet digital detection. |
2019 |
Lab Chip |
| Anephrogenic phenotype induced by SALL1 gene knockout in pigs. |
2019 |
Sci Rep |
| Anti-CD117 antibody depletes normal and myelodysplastic syndrome human hematopoietic stem cells in xenografted mice. |
2019 |
Blood |
| Anti-human CD117 antibody-mediated bone marrow niche clearance in nonhuman primates and humanized NSG mice. |
2019 |
Blood |
| Antibody Conditioning Enables MHC-Mismatched Hematopoietic Stem Cell Transplants and Organ Graft Tolerance. |
2019 |
Cell Stem Cell |
| Atoh1 Directs Regeneration and Functional Recovery of the Mature Mouse Vestibular System. |
2019 |
Cell Rep |
| Atoh1(+) secretory progenitors possess renewal capacity independent of Lgr5(+) cells during colonic regeneration. |
2019 |
EMBO J |
| Automated Design of Pluripotent Stem Cell Self-Organization. |
2019 |
Cell Syst |
| betaDiketonate-Iron(III) Complex: A Versatile Fluorine-19 MRI Signal Enhancement Agent. |
2019 |
ACS Appl Bio Mater |
| Biological process activity transformation of single cell gene expression for cross-species alignment. |
2019 |
Nat Commun |
| Biomaterials for tissue repair. |
2019 |
Science |
| Bortezomib Augments Natural Killer Cell Targeting of Stem-Like Tumor Cells. |
2019 |
Cancers (Basel) |
| Bovine pericardial extracellular matrix niche modulates human aortic endothelial cell phenotype and function. |
2019 |
Sci Rep |
| Brain organoids as a model system for human neurodevelopment and disease. |
2019 |
Semin Cell Dev Biol |
| Brain Organoids as Tools for Modeling Human Neurodevelopmental Disorders. |
2019 |
Physiology (Bethesda) |
| CaMKII inhibition in human primary and pluripotent stem cell-derived chondrocytes modulates effects of TGFbeta and BMP through SMAD signaling. |
2019 |
Osteoarthritis Cartilage |
| Cardiac and skeletal muscle effects in the randomized HOPE-Duchenne trial. |
2019 |
Neurology |
| Cardiac fibrosis: potential therapeutic targets. |
2019 |
Transl Res |
| CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy. |
2019 |
Nature |
| Chasing Mavericks: The quest for defining developmental waves of hematopoiesis. |
2019 |
Curr Top Dev Biol |
| Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-beta in iPSC-Derived Alzheimer’s Disease Neurons. |
2019 |
Cell Stem Cell |
| Chronic myelogenous leukemia stem cells require cell-autonomous pleiotrophin signaling. |
2019 |
J Clin Invest |
| Circulating tumor cells exhibit metastatic tropism and reveal brain metastasis drivers. |
2019 |
Cancer Discov |
| Classification of Limbal Stem Cell Deficiency Using Clinical and Confocal Grading. |
2019 |
Cornea |
| Combinatorial targeting of cancer bone metastasis using mRNA engineered stem cells. |
2019 |
EBioMedicine |
| Comparison of endothelial keratoplasty techniques in patients with prior glaucoma surgery – a case-matched study. |
2019 |
Am J Ophthalmol |
| Complex Oscillatory Waves Emerging from Cortical Organoids Model Early Human Brain Network Development. |
2019 |
Cell Stem Cell |
| CRISPR-mediated activation of a promoter or enhancer rescues obesity caused by haploinsufficiency. |
2019 |
Science |
| CTCF sites display cell cycle-dependent dynamics in factor binding and nucleosome positioning. |
2019 |
Genome Res |
| Determining cellular CTCF and cohesin abundances to constrain 3D genome models. |
2019 |
Elife |
| Determining the pharmacokinetics of nicotinic drugs in the endoplasmic reticulum using biosensors. |
2019 |
J Gen Physiol |
| Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo. |
2019 |
Neuron |
| Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer. |
2019 |
Cell Stem Cell |
| Development of innate immune cells from human pluripotent stem cells. |
2019 |
Exp Hematol |
| Diagnostic criteria for limbal stem cell deficiency before surgical intervention-A systematic literature review and analysis. |
2019 |
Surv Ophthalmol |
| Direct Reprogramming of Human Neurons Identifies MARCKSL1 as a Pathogenic Mediator of Valproic Acid-Induced Teratogenicity. |
2019 |
Cell Stem Cell |
| Distinct Classes of Chromatin Loops Revealed by Deletion of an RNA-Binding Region in CTCF. |
2019 |
Mol Cell |
| Editing the Sickle Cell Disease Mutation in Human Hematopoietic Stem Cells: Comparison of Endonucleases and Homologous Donor Templates. |
2019 |
Mol Ther |
| Effect of inoculum density on human-induced pluripotent stem cell expansion in 3D bioreactors. |
2019 |
Cell Prolif |
| Effects of Spaceflight and Simulated Microgravity on YAP1 Expression in Cardiovascular Progenitors: Implications for Cell-Based Repair. |
2019 |
Int J Mol Sci |
| Efficient Differentiation of Human Pluripotent Stem Cells into Liver Cells. |
2019 |
J Vis Exp |
| Enhanced Delivery of Oncolytic Adenovirus by Neural Stem Cells for Treatment of Metastatic Ovarian Cancer. |
2019 |
Mol Ther Oncolytics |
| Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution. |
2019 |
Cell |
| Evaluating phase separation in live cells: diagnosis, caveats, and functional consequences. |
2019 |
Genes Dev |
| Evidence for DNA-mediated nuclear compartmentalization distinct from phase separation. |
2019 |
Elife |
| Fiber-based platform for synchronous imaging of endogenous and exogenous fluorescence of biological tissue. |
2019 |
Opt Lett |
