Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Directed Dopaminergic Neuron Differentiation from Human Pluripotent Stem Cells. 2014 J Vis Exp
Discovery of consensus gene signature and intermodular connectivity defining self-renewal of human embryonic stem cells. 2014 Stem Cells
Discriminating cellular heterogeneity using microwell-based RNA cytometry. 2014 Nat Commun
Disruption of Cerebrospinal Fluid Flow through the Olfactory System May Contribute to Alzheimer’s Disease Pathogenesis. 2014 J Alzheimers Dis
Distinct and separable roles for EZH2 in neurogenic astroglia. 2014 Elife
Distinct phases in the positive selection of CD8+ T cells distinguished by intrathymic migration and T-cell receptor signaling patterns. 2014 Proc Natl Acad Sci U S A
Drugging a stem cell compartment using wnt3a protein as a therapeutic. 2014 PLoS One
Dynamic Changes in Intracellular ROS Levels Regulate Airway Basal Stem Cell Homeostasis through Nrf2-Dependent Notch Signaling. 2014 Cell Stem Cell
Dynamics of HSPC repopulation in nonhuman primates revealed by a decade-long clonal-tracking study. 2014 Cell Stem Cell
Efficient derivation of cortical glutamatergic neurons from human pluripotent stem cells: a model system to study neurotoxicity in Alzheimer’s disease. 2014 Neurobiol Dis
Efficient Endoderm Induction from Human Pluripotent Stem Cells by Logically Directing Signals Controlling Lineage Bifurcations. 2014 Cell Stem Cell
Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation. 2014 Immunity
Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer. 2014 Nature
Endogenous WNT Signaling Regulates hPSC-Derived Neural Progenitor Cell Heterogeneity and Specifies Their Regional Identity. 2014 Stem Cell Reports
Engineering interpenetrating network hydrogels as biomimetic cell niche with independently tunable biochemical and mechanical properties. 2014 Biomaterials
Engineering strategies to mimic the glioblastoma microenvironment. 2014 Adv Drug Deliv Rev
Engineering the human thymic microenvironment to support thymopoiesis in vivo. 2014 Stem Cells
Enhanced gene targeting of adult and pluripotent stem cells using evolved adeno-associated virus. 2014 Methods Mol Biol
Enhanced Genetic Modification of Adult Growth Factor Mobilized Peripheral Blood Hematopoietic Stem and Progenitor Cells With Rapamycin. 2014 Stem Cells Transl Med
Enhanced trophic factor secretion by mesenchymal stem/stromal cells with Glycine-Histidine-Lysine (GHK)-modified alginate hydrogels. 2014 Acta Biomater
Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma. 2014 Nature
Enhancer-trap Flippase Lines for Clonal Analysis in the Drosophila Ovary. 2014 G3 (Bethesda)
Epigenetic regulation of pluripotency and differentiation. 2014 Circ Res
Epigenetic therapy for Friedreich ataxia. 2014 Ann Neurol
Erythropoiesis from human embryonic stem cells through erythropoietin-independent AKT signaling. 2014 Stem Cells
Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency. 2014 Elife
Evidence against a Stem Cell Origin of New Hepatocytes in a Common Mouse Model of Chronic Liver Injury. 2014 Cell Rep
Evidence that the DNA endonuclease ARTEMIS also has intrinsic 5′-exonuclease activity. 2014 J Biol Chem
Existing cardiomyocytes generate cardiomyocytes at a low rate after birth in mice. 2014 Proc Natl Acad Sci U S A
Fate of induced pluripotent stem cells following transplantation to murine seminiferous tubules. 2014 Hum Mol Genet
Fate of iPSCs Derived from Azoospermic and Fertile Men following Xenotransplantation to Murine Seminiferous Tubules. 2014 Cell Rep
Fetal Intervention Increases Maternal T Cell Awareness of the Foreign Conceptus and Can Lead to Immune-Mediated Fetal Demise. 2014 J Immunol
Follistatin interacts with Noggin in the development of the axial skeleton. 2014 Mech Dev
Gastrointestinal microbes interact with canine adipose-derived mesenchymal stem cells in vitro and enhance immunomodulatory functions. 2014 Stem Cells Dev
Gene expression signatures affected by alcohol-induced DNA methylomic deregulation in human embryonic stem cells. 2014 Stem Cell Res
Generation of Induced Neuronal Cells by the Single Reprogramming Factor ASCL1. 2014 Stem Cell Reports
Generation of multiciliated cells in functional airway epithelia from human induced pluripotent stem cells. 2014 Proc Natl Acad Sci U S A
Generation, Expansion, and Differentiation of Human Induced Pluripotent Stem Cells (hiPSCs) Derived From the Umbilical Cords of Newborns. 2014 Curr Protoc Stem Cell Biol
Genetic removal of matrix metalloproteinase 9 rescues the symptoms of fragile x syndrome in a mouse model. 2014 J Neurosci
Genome wide profiling of dopaminergic neurons derived from human embryonic and induced pluripotent stem cells. 2014 Stem Cells Dev
Genomic instability in pluripotent stem cells: implications for clinical applications. 2014 J Biol Chem
Germ-Granule Components Prevent Somatic Development in the C. elegans Germline. 2014 Curr Biol
GPBAR1/TGR5 mediates bile acid-induced cytokine expression in murine Kupffer cells. 2014 PLoS One
Hierarchical molecular events driven by oocyte-specific factors lead to rapid and extensive reprogramming. 2014 Mol Cell
HIPPO pathway members restrict SOX2 to the inner cell mass where it promotes ICM fates in the mouse blastocyst. 2014 PLoS Genet
Histone H3.3 regulates dynamic chromatin states during spermatogenesis. 2014 Development
HSV-sr39TK positron emission tomography and suicide gene elimination of human hematopoietic stem cells and their progeny in humanized mice. 2014 Cancer Res
Human cardiosphere-derived cells from advanced heart failure patients exhibit augmented functional potency in myocardial repair. 2014 JACC Heart Fail
Human COL7A1-corrected induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa. 2014 Sci Transl Med
Human cytomegalovirus infection of human embryonic stem cell-derived primitive neural stem cells is restricted at several steps but leads to the persistence of viral DNA. 2014 J Virol