Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Regenerative medicine: is this the biggest change in surgery? 2014 Semin Pediatr Surg
Regulation of iPS Cell Induction by Wnt/beta-catenin Signaling. 2014 J Biol Chem
Rejuvenation of the muscle stem cell population restores strength to injured aged muscles. 2014 Nat Med
Reliable Generation of Induced Pluripotent Stem Cells From Human Lymphoblastoid Cell Lines. 2014 Stem Cells Transl Med
Reorganization of enhancer patterns in transition from naive to primed pluripotency. 2014 Cell Stem Cell
Replication of Mycobacterium tuberculosis in retinal pigment epithelium. 2014 JAMA Ophthalmol
Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells. 2014 Nature
Reprogramming by lineage specifiers: blurring the lines between pluripotency and differentiation. 2014 Curr Opin Genet Dev
Reprogramming Human Retinal Pigmented Epithelial Cells to Neurons Using Recombinant Proteins. 2014 Stem Cells Transl Med
Research capacity. Enabling the genomic revolution in Africa. 2014 Science
ROCK Inhibition Extends Passage of Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium. 2014 Stem Cells Transl Med
Role of astroglia in Down’s syndrome revealed by patient-derived human-induced pluripotent stem cells. 2014 Nat Commun
Role of BRCA1 in brain development. 2014 Proc Natl Acad Sci U S A
Roles of heat shock factor 1 in neuronal response to fetal environmental risks and its relevance to brain disorders. 2014 Neuron
Serine integrase chimeras with activity in E. coli and HeLa cells. 2014 Biol Open
Sexually dimorphic effect of in vitro fertilization (IVF) on adult mouse fat and liver metabolomes. 2014 Endocrinology
Shaking up the salt and pepper: origins of cellular heterogeneity in the inner cell mass of the blastocyst. 2014 EMBO J
Signaling pathways in induced naive pluripotency. 2014 Curr Opin Genet Dev
Single-cell gene expression profiles define self-renewing, pluripotent, and lineage primed States of human pluripotent stem cells. 2014 Stem Cell Reports
Single-cell trajectory detection uncovers progression and regulatory coordination in human B cell development. 2014 Cell
Single-cell western blotting. 2014 Nat Methods
Single-molecule super-resolution light-sheet microscopy. 2014 Chemphyschem
SLIT/ROBO2 Signaling Promotes Mammary Stem Cell Senescence by Inhibiting Wnt Signaling. 2014 Stem Cell Reports
Small molecules enable cardiac reprogramming of mouse fibroblasts with a single factor, Oct4. 2014 Cell Rep
Somatic correction of junctional epidermolysis bullosa by a highly recombinogenic AAV variant. 2014 Mol Ther
Spatiotemporally different origins of NG2 progenitors produce cortical interneurons versus glia in the mammalian forebrain. 2014 Proc Natl Acad Sci U S A
Specialized mouse embryonic stem cells for studying vascular development. 2014 Stem Cells Cloning
Sphingosine phosphate lyase regulates myogenic differentiation via S1P receptor-mediated effects on myogenic microRNA expression. 2014 FASEB J
Splicing factor TRA2B is required for neural progenitor survival. 2014 J Comp Neurol
Spontaneous hair cell regeneration in the neonatal mouse cochlea in vivo. 2014 Development
sRNA-seq analysis of human embryonic stem cells and definitive endoderm reveal differentially expressed microRNAs and novel isomiRs with distinct targets. 2014 Stem Cells
STAT3 Phosphorylation at Tyrosine 705 and Serine 727 Differentially Regulates Mouse ESC Fates. 2014 Stem Cells
STAT3 signaling controls satellite cell expansion and skeletal muscle repair. 2014 Nat Med
Stat3 signaling regulates embryonic stem cell fate in a dose-dependent manner. 2014 Biol Open
Stem cells and biopharmaceuticals: vital roles in the growth of tissue-engineered small intestine. 2014 Semin Pediatr Surg
Stimulation of endogenous cardioblasts by exogenous cell therapy after myocardial infarction. 2014 EMBO Mol Med
Stress and glucocorticoids promote oligodendrogenesis in the adult hippocampus. 2014 Mol Psychiatry
Survival and engraftment of dopaminergic neurons manufactured by a Good Manufacturing Practice-compatible process. 2014 Cytotherapy
Synaptic dysregulation in a human iPS cell model of mental disorders. 2014 Nature
Synthetic control of mammalian-cell motility by engineering chemotaxis to an orthogonal bioinert chemical signal. 2014 Proc Natl Acad Sci U S A
Systematic Identification of Barriers to Human iPSC Generation. 2014 Cell
Targeted delivery of mesenchymal stem cells to the bone. 2014 Bone
Targeted gene correction minimally impacts whole-genome mutational load in human-disease-specific induced pluripotent stem cell clones. 2014 Cell Stem Cell
Tbr2 is required to generate a neural circuit mediating the pupillary light reflex. 2014 J Neurosci
Tbx1 controls the morphogenesis of pharyngeal pouch epithelia through mesodermal Wnt11r and Fgf8a. 2014 Development
Technical Variations in Low-Input RNA-seq Methodologies. 2014 Sci Rep
Techniques to monitor glycolysis. 2014 Methods Enzymol
Telomerase governs immunomodulatory properties of mesenchymal stem cells by regulating FAS ligand expression. 2014 EMBO Mol Med
TET2 plays an essential role in erythropoiesis by regulating lineage-specific genes via DNA oxidative demethylation in a zebrafish model. 2014 Mol Cell Biol
The adult livers of immunodeficient mice support human hematopoiesis: evidence for a hepatic mast cell population that develops early in human ontogeny. 2014 PLoS One