Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice. 2014 Nat Med
A “living bioreactor” for the production of tissue-engineered small intestine. 2013 Methods Mol Biol
A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis. 2013 Elife
A critical role for AID in the initiation of reprogramming to induced pluripotent stem cells. 2013 FASEB J
A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors. 2013 Cancer Discov
A dynamic population of stromal cells contributes to the follicle stem cell niche in the Drosophila ovary. 2013 Development
A far downstream enhancer for murine Bcl11b controls its T-cell specific expression. 2013 Blood
A fully defined and scalable 3D culture system for human pluripotent stem cell expansion and differentiation. 2013 Proc Natl Acad Sci U S A
A High-Resolution Enhancer Atlas of the Developing Telencephalon. 2013 Cell
A high-resolution map of the three-dimensional chromatin interactome in human cells. 2013 Nature
A localized Wnt signal orients asymmetric stem cell division in vitro. 2013 Science
A Pan-BCL2 inhibitor renders bone-marrow-resident human leukemia stem cells sensitive to tyrosine kinase inhibition. 2013 Cell Stem Cell
A population of Nestin-expressing progenitors in the cerebellum exhibits increased tumorigenicity. 2013 Nat Neurosci
A rare population of CD24(+)ITGB4(+)Notch(hi) cells drives tumor propagation in NSCLC and requires Notch3 for self-renewal. 2013 Cancer Cell
A regenerative approach to the treatment of multiple sclerosis. 2013 Nature
A robust method to derive functional neural crest cells from human pluripotent stem cells. 2013 Am J Stem Cells
A small molecule inhibitor of redox-regulated protein translocation into mitochondria. 2013 Dev Cell
A Three-Dimensional Culture Method to Expand Limbal Stem/Progenitor Cells. 2013 Tissue Eng Part C Methods
Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells. 2013 Cell Stem Cell
Acute stress enhances adult rat hippocampal neurogenesis and activation of newborn neurons via secreted astrocytic FGF2. 2013 Elife (Cambridge)
Adding an unnatural covalent bond to proteins through proximity-enhanced bioreactivity. 2013 Nat Methods
Age-related behavioral phenotype of an astrocytic monoamine oxidase-B transgenic mouse model of Parkinson’s disease. 2013 PLoS One
Ago1 Interacts with RNA polymerase II and binds to the promoters of actively transcribed genes in human cancer cells. 2013 PLoS Genet
All’s well that ends well: alternative polyadenylation and its implications for stem cell biology. 2013 Curr Opin Cell Biol
Allelic Exclusion and Peripheral Reconstitution by TCR Transgenic T Cells Arising From Transduced Human Hematopoietic Stem/Progenitor Cells. 2013 Mol Ther
Allogeneic cardiospheres safely boost cardiac function and attenuate adverse remodeling after myocardial infarction in immunologically mismatched rat strains. 2013 J Am Coll Cardiol
AMPD2 regulates GTP synthesis and is mutated in a potentially treatable neurodegenerative brainstem disorder. 2013 Cell
Amyloid beta peptide cleavage by kallikrein 7 attenuates fibril growth and rescues neurons from Abeta mediated toxicity in vitro. 2013 Biol Chem
Amyloid-beta Increases Capillary Bed Density in the Adult Zebrafish Retina. 2013 Invest Ophthalmol Vis Sci
An indirect approach to generating specific human cell types. 2013 Nat Methods
Analysis of protein-coding mutations in hiPSCs and their possible role during somatic cell reprogramming. 2013 Nat Commun
Analysis of SOX2-Expressing Cell Populations Derived from Human Pluripotent Stem Cells. 2013 Stem Cell Reports
Astroglial cells regulate the developmental timeline of human neurons differentiated from induced pluripotent stem cells. 2013 Stem Cell Res
Augmenting endogenous Wnt signaling improves skin wound healing. 2013 PLoS One
BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint. 2013 Nat Med
Back to the future: how human induced pluripotent stem cells will transform regenerative medicine. 2013 Hum Mol Genet
Berbamine inhibits the growth of liver cancer cells and cancer-initiating cells by targeting Ca(2)(+)/calmodulin-dependent protein kinase II. 2013 Mol Cancer Ther
beta-globin gene transfer to human bone marrow for sickle cell disease. 2013 J Clin Invest
beta2-Microglobulin-free HLA-G activates natural killer cells by increasing cytotoxicity and proinflammatory cytokine production. 2013 Hum Immunol
Bile Acid Receptors and Liver Cancer. 2013 Curr Pathobiol Rep
Bivalent Chromatin Marks Developmental Regulatory Genes in the Mouse Embryonic Germline In Vivo. 2013 Cell Rep
BMI1 represses Ink4a/Arf and Hox genes to regulate stem cells in the rodent incisor. 2013 Nat Cell Biol
BMP4-directed trophoblast differentiation of human embryonic stem cells is mediated through a DeltaNp63+ cytotrophoblast stem cell state. 2013 Development
Bone marrow-derived cell therapy after myocardial infarction–reply. 2013 JAMA
Breaking down protein degradation mechanisms in cardiac muscle. 2013 Trends Mol Med
Brg1 governs distinct pathways to direct multiple aspects of mammalian neural crest cell development. 2013 Proc Natl Acad Sci U S A
Call for fellowship programs in stem cell-based regenerative and cellular medicine: new stem cell training is essential for physicians. 2013 Regen Med
Cancer cells acquire a drug resistant, highly tumorigenic, cancer stem-like phenotype through modulation of the PI3K/Akt/beta-catenin/CBP pathway. 2013 Int J Cancer
Cardiomyocyte proliferation and progenitor cell recruitment underlie therapeutic regeneration after myocardial infarction in the adult mouse heart. 2013 EMBO Mol Med
Cerebellar Cortical Lamination and Foliation Require Cyclin A2. 2013 Dev Biol