Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Studying arrhythmogenic right ventricular dysplasia with patient-specific iPSCs. 2013 Nature
Synovial stem cells and their responses to the porosity of microfibrous scaffold. 2013 Acta Biomater
Synthesis of a photocaged tamoxifen for light-dependent activation of Cre-ER recombinase-driven gene modification. 2013 Chem Commun (Camb)
TACE in perinatal mouse lung epithelial cells promotes lung saccular formation. 2013 Am J Physiol Lung Cell Mol Physiol
Targeted MicroRNA Interference Promotes Postnatal Cardiac Cell Cycle Re-Entry. 2013 J Regen Med
Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion. 2013 Sci Transl Med
Targeting sonic hedgehog-associated medulloblastoma through inhibition of Aurora and Polo-like kinases. 2013 Cancer Res
Tet1 regulates adult hippocampal neurogenesis and cognition. 2013 Cell Stem Cell
TETonic shift: biological roles of TET proteins in DNA demethylation and transcription. 2013 Nat Rev Mol Cell Biol
The candidate histocompatibility locus of a Basal chordate encodes two highly polymorphic proteins. 2013 PLoS One
The circulatory systemic environment as a modulator of neurogenesis and brain aging. 2013 Autoimmun Rev
The Colossus of ubiquitylation: decrypting a cellular code. 2013 Mol Cell
The effect of a peptide-modified thermo-reversible methylcellulose on wound healing and LV function in a chronic myocardial infarction rodent model. 2013 Biomaterials
The functional genetic link of NLGN4X knockdown and neurodevelopment in neural stem cells. 2013 Hum Mol Genet
The interactomes of POU5F1 and SOX2 enhancers in human embryonic stem cells. 2013 Sci Rep
The intertwined roles of transcription and repair proteins. 2013 Mol Cell
The Migration of Hematopoietic Progenitors from the Fetal Liver to the Fetal Bone Marrow: Lessons Learned and Possible Clinical Applications. 2013 Exp Hematol
The Pluripotency Factor-Bound Intron 1 of Xist Is Dispensable for X Chromosome Inactivation and Reactivation In Vitro and In Vivo. 2013 Cell Rep
The Presenilin-1 DeltaE9 Mutation Results in Reduced gamma-Secretase Activity, but Not Total Loss of PS1 Function, in Isogenic Human Stem Cells. 2013 Cell Rep
The TBC1D15 Oncoprotein Controls Stem Cell Self-Renewal through Destabilization of the Numb-p53 Complex. 2013 PLoS One
The trithorax group proteins Kismet and ASH1 promote H3K36 dimethylation to counteract Polycomb group repression in Drosophila. 2013 Development
The viral oncogene Np9 acts as a critical molecular switch for co-activating beta-catenin, ERK, Akt and Notch1 and promoting the growth of human leukemia stem/progenitor cells. 2013 Leukemia
The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome. 2013 Science
Thrombin-mediated activation of Akt signaling contributes to pulmonary vascular remodeling in pulmonary hypertension. 2013 Physiol Rep
Timothy syndrome is associated with activity-dependent dendritic retraction in rodent and human neurons. 2013 Nat Neurosci
Tissue Engineering the Small Intestine. 2013 Clin Gastroenterol Hepatol
Tissue engineering: a promising therapeutic approach to necrotizing enterocolitis. 2013 Semin Pediatr Surg
Tissue specificity of decellularized rhesus monkey kidney and lung scaffolds. 2013 PLoS One
Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes. 2013 Immunity
Topology of feather melanocyte progenitor niche allows complex pigment patterns to emerge. 2013 Science
Tracking immune cells in vivo using magnetic resonance imaging. 2013 Nat Rev Immunol
Transcriptome sequencing of tumor subpopulations reveals a spectrum of therapeutic options for squamous cell lung cancer. 2013 PLoS One
Transdifferentiation and remodeling of post-embryonic C. elegans cells by a single transcription factor. 2013 Development
Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position. 2013 Nat Methods
Tumor suppressors: enhancers or suppressors of regeneration? 2013 Development
Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies. 2013 Nat Med
Twenty-fold acceleration of 3D projection reconstruction MPI. 2013 Biomed Tech (Berl)
TYK2-STAT1-BCL2 Pathway Dependence in T-cell Acute Lymphoblastic Leukemia. 2013 Cancer Discov
Type 2 innate signals stimulate fibro/adipogenic progenitors to facilitate muscle regeneration. 2013 Cell
Understanding telomere diseases through analysis of patient-derived iPS cells. 2013 Curr Opin Genet Dev
Use of “MGE Enhancers” for Labeling and Selection of Embryonic Stem Cell-Derived Medial Ganglionic Eminence (MGE) Progenitors and Neurons. 2013 PLoS One
Use of a molecular genetic platform technology to produce human wnt proteins reveals distinct local and distal signaling abilities. 2013 PLoS One
Using human pluripotent stem cell-derived dopaminergic neurons to evaluate candidate Parkinson’s disease therapeutic agents in MPP+ and rotenone models. 2013 J Biomol Screen
Using shape effects to target antibody-coated nanoparticles to lung and brain endothelium. 2013 Proc Natl Acad Sci U S A
Usp16 contributes to somatic stem-cell defects in Down’s syndrome. 2013 Nature
Validation of contrast-enhanced magnetic resonance imaging to monitor regenerative efficacy after cell therapy in a porcine model of convalescent myocardial infarction. 2013 Circulation
Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells. 2013 Nature
Whole transcriptome sequencing enables discovery and analysis of viruses in archived primary central nervous system lymphomas. 2013 PLoS One
Wnt signaling regulates pulp volume and dentin thickness. 2013 J Bone Miner Res
Wnt-Dependent Epithelial Transitions Drive Pharyngeal Pouch Formation. 2013 Dev Cell