Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
The TBC1D15 Oncoprotein Controls Stem Cell Self-Renewal through Destabilization of the Numb-p53 Complex. 2013 PLoS One
The trithorax group proteins Kismet and ASH1 promote H3K36 dimethylation to counteract Polycomb group repression in Drosophila. 2013 Development
The viral oncogene Np9 acts as a critical molecular switch for co-activating beta-catenin, ERK, Akt and Notch1 and promoting the growth of human leukemia stem/progenitor cells. 2013 Leukemia
The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome. 2013 Science
Thrombin-mediated activation of Akt signaling contributes to pulmonary vascular remodeling in pulmonary hypertension. 2013 Physiol Rep
Timothy syndrome is associated with activity-dependent dendritic retraction in rodent and human neurons. 2013 Nat Neurosci
Tissue Engineering the Small Intestine. 2013 Clin Gastroenterol Hepatol
Tissue engineering: a promising therapeutic approach to necrotizing enterocolitis. 2013 Semin Pediatr Surg
Tissue specificity of decellularized rhesus monkey kidney and lung scaffolds. 2013 PLoS One
Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes. 2013 Immunity
Topology of feather melanocyte progenitor niche allows complex pigment patterns to emerge. 2013 Science
Tracking immune cells in vivo using magnetic resonance imaging. 2013 Nat Rev Immunol
Transcriptome sequencing of tumor subpopulations reveals a spectrum of therapeutic options for squamous cell lung cancer. 2013 PLoS One
Transdifferentiation and remodeling of post-embryonic C. elegans cells by a single transcription factor. 2013 Development
Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position. 2013 Nat Methods
Tumor suppressors: enhancers or suppressors of regeneration? 2013 Development
Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies. 2013 Nat Med
Twenty-fold acceleration of 3D projection reconstruction MPI. 2013 Biomed Tech (Berl)
TYK2-STAT1-BCL2 Pathway Dependence in T-cell Acute Lymphoblastic Leukemia. 2013 Cancer Discov
Type 2 innate signals stimulate fibro/adipogenic progenitors to facilitate muscle regeneration. 2013 Cell
Understanding telomere diseases through analysis of patient-derived iPS cells. 2013 Curr Opin Genet Dev
Use of “MGE Enhancers” for Labeling and Selection of Embryonic Stem Cell-Derived Medial Ganglionic Eminence (MGE) Progenitors and Neurons. 2013 PLoS One
Use of a molecular genetic platform technology to produce human wnt proteins reveals distinct local and distal signaling abilities. 2013 PLoS One
Using human pluripotent stem cell-derived dopaminergic neurons to evaluate candidate Parkinson’s disease therapeutic agents in MPP+ and rotenone models. 2013 J Biomol Screen
Using shape effects to target antibody-coated nanoparticles to lung and brain endothelium. 2013 Proc Natl Acad Sci U S A
Usp16 contributes to somatic stem-cell defects in Down’s syndrome. 2013 Nature
Validation of contrast-enhanced magnetic resonance imaging to monitor regenerative efficacy after cell therapy in a porcine model of convalescent myocardial infarction. 2013 Circulation
Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells. 2013 Nature
Whole transcriptome sequencing enables discovery and analysis of viruses in archived primary central nervous system lymphomas. 2013 PLoS One
Wnt signaling regulates pulp volume and dentin thickness. 2013 J Bone Miner Res
Wnt-Dependent Epithelial Transitions Drive Pharyngeal Pouch Formation. 2013 Dev Cell
Wnt3a reestablishes osteogenic capacity to bone grafts from aged animals. 2013 J Bone Joint Surg Am
Wnt7a regulates multiple steps of neurogenesis. 2013 Mol Cell Biol
Wnt7b is an important intrinsic regulator of hair follicle stem cell homeostasis and hair follicle cycling. 2013 Stem Cells
A homozygous IER3IP1 mutation causes microcephaly with simplified gyral pattern, epilepsy, and permanent neonatal diabetes syndrome (MEDS). 2012 Am J Med Genet A
A Lissencephaly-1 homologue is essential for mitotic progression in the planarian Schmidtea mediterranea. 2012 Dev Dyn
A map of the cis-regulatory sequences in the mouse genome. 2012 Nature
A microRNA-21 surge facilitates rapid cyclin D1 translation and cell cycle progression in mouse liver regeneration. 2012 J Clin Invest
A molecular signature for purified definitive endoderm guides differentiation and isolation of endoderm from mouse and human embryonic stem cells. 2012 Stem Cells Dev
A Novel Approach for Subretinal Implantation of Ultrathin Substrates Containing Stem Cell-Derived Retinal Pigment Epithelium Monolayer. 2012 Ophthalmic Res
A novel dual-color reporter for identifying insulin-producing beta-cells and classifying heterogeneity of insulinoma cell lines. 2012 PLoS One
A Novel Regulatory Factor Recruits the Nucleosome Remodeling Complex to Wingless Integrated (WNT) Signaling Gene Promoters in Mouse Embryonic Stem cells. 2012 J Biol Chem
A resource for the conditional ablation of microRNAs in the mouse. 2012 Cell Rep
A roundabout way to cancer. 2012 Adv Cancer Res
A scalable approach to prevent teratoma formation of human embryonic stem cells. 2012 J Biol Chem
A scalable system for production of functional pancreatic progenitors from human embryonic stem cells. 2012 PLoS One
A self-limiting switch based on translational control regulates the transition from proliferation to differentiation in an adult stem cell lineage. 2012 Cell Stem Cell
A single cell bioengineering approach to elucidate mechanisms of adult stem cell self-renewal. 2012 Integr Biol (Camb)
A Sox9/Fgf feed-forward loop maintains pancreatic organ identity. 2012 Development
A stable cranial neural crest cell line from mouse. 2012 Stem Cells Dev