Publications by Grantees

CIRM funding supported the following publications. Click on the publication title for a brief summary of the research and for more information:

Title Year Journal
Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position. 2013 Nat Methods
Tumor suppressors: enhancers or suppressors of regeneration? 2013 Development
Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies. 2013 Nat Med
Twenty-fold acceleration of 3D projection reconstruction MPI. 2013 Biomed Tech (Berl)
TYK2-STAT1-BCL2 Pathway Dependence in T-cell Acute Lymphoblastic Leukemia. 2013 Cancer Discov
Type 2 innate signals stimulate fibro/adipogenic progenitors to facilitate muscle regeneration. 2013 Cell
Understanding telomere diseases through analysis of patient-derived iPS cells. 2013 Curr Opin Genet Dev
Use of “MGE Enhancers” for Labeling and Selection of Embryonic Stem Cell-Derived Medial Ganglionic Eminence (MGE) Progenitors and Neurons. 2013 PLoS One
Use of a molecular genetic platform technology to produce human wnt proteins reveals distinct local and distal signaling abilities. 2013 PLoS One
Using human pluripotent stem cell-derived dopaminergic neurons to evaluate candidate Parkinson’s disease therapeutic agents in MPP+ and rotenone models. 2013 J Biomol Screen
Using shape effects to target antibody-coated nanoparticles to lung and brain endothelium. 2013 Proc Natl Acad Sci U S A
Usp16 contributes to somatic stem-cell defects in Down’s syndrome. 2013 Nature
Validation of contrast-enhanced magnetic resonance imaging to monitor regenerative efficacy after cell therapy in a porcine model of convalescent myocardial infarction. 2013 Circulation
Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells. 2013 Nature
Whole transcriptome sequencing enables discovery and analysis of viruses in archived primary central nervous system lymphomas. 2013 PLoS One
Wnt signaling regulates pulp volume and dentin thickness. 2013 J Bone Miner Res
Wnt-Dependent Epithelial Transitions Drive Pharyngeal Pouch Formation. 2013 Dev Cell
Wnt3a reestablishes osteogenic capacity to bone grafts from aged animals. 2013 J Bone Joint Surg Am
Wnt7a regulates multiple steps of neurogenesis. 2013 Mol Cell Biol
Wnt7b is an important intrinsic regulator of hair follicle stem cell homeostasis and hair follicle cycling. 2013 Stem Cells
A homozygous IER3IP1 mutation causes microcephaly with simplified gyral pattern, epilepsy, and permanent neonatal diabetes syndrome (MEDS). 2012 Am J Med Genet A
A Lissencephaly-1 homologue is essential for mitotic progression in the planarian Schmidtea mediterranea. 2012 Dev Dyn
A map of the cis-regulatory sequences in the mouse genome. 2012 Nature
A microRNA-21 surge facilitates rapid cyclin D1 translation and cell cycle progression in mouse liver regeneration. 2012 J Clin Invest
A molecular signature for purified definitive endoderm guides differentiation and isolation of endoderm from mouse and human embryonic stem cells. 2012 Stem Cells Dev
A Novel Approach for Subretinal Implantation of Ultrathin Substrates Containing Stem Cell-Derived Retinal Pigment Epithelium Monolayer. 2012 Ophthalmic Res
A novel dual-color reporter for identifying insulin-producing beta-cells and classifying heterogeneity of insulinoma cell lines. 2012 PLoS One
A Novel Regulatory Factor Recruits the Nucleosome Remodeling Complex to Wingless Integrated (WNT) Signaling Gene Promoters in Mouse Embryonic Stem cells. 2012 J Biol Chem
A resource for the conditional ablation of microRNAs in the mouse. 2012 Cell Rep
A roundabout way to cancer. 2012 Adv Cancer Res
A scalable approach to prevent teratoma formation of human embryonic stem cells. 2012 J Biol Chem
A scalable system for production of functional pancreatic progenitors from human embryonic stem cells. 2012 PLoS One
A self-limiting switch based on translational control regulates the transition from proliferation to differentiation in an adult stem cell lineage. 2012 Cell Stem Cell
A single cell bioengineering approach to elucidate mechanisms of adult stem cell self-renewal. 2012 Integr Biol (Camb)
A Sox9/Fgf feed-forward loop maintains pancreatic organ identity. 2012 Development
A stable cranial neural crest cell line from mouse. 2012 Stem Cells Dev
A Stem Cell-Based Approach to Cartilage Repair. 2012 Science
A ZFN/piggyBac step closer to autologous liver cell therapy. 2012 Hepatology
Absence of CCL2 is sufficient to restore hippocampal neurogenesis following cranial irradiation. 2012 Brain Behav Immun
Absence of sclerostin adversely affects B cell survival. 2012 J Bone Miner Res
Active chromatin and noncoding RNAs: an intimate relationship. 2012 Curr Opin Genet Dev
Activin A and BMP4 Signaling for Efficient Cardiac Differentiation of H7 and H9 Human Embryonic Stem Cells. 2012 J Stem Cells Regen Med
ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia. 2012 Proc Natl Acad Sci U S A
Additive Effects of Sonic Hedgehog and Nell-1 Signaling in Osteogenic versus Adipogenic Differentiation of Human Adipose-Derived Stromal Cells. 2012 Stem Cells Dev
Adoptive transfer of induced-treg cells effectively attenuates murine airway allergic inflammation. 2012 PLoS One
Advances in the biology and therapy of chronic myeloid leukemia: proceedings from the 6th Post-ASH International Chronic Myeloid Leukemia and Myeloproliferative Neoplasms Workshop. 2012 Leuk Lymphoma
Advances in treatment and management: immunologic and cell-based regenerative therapies. 2012 Invest Ophthalmol Vis Sci
Advancing practical usage of microtechnology: a study of the functional consequences of dielectrophoresis on neural stem cells. 2012 Integr Biol (Camb)
Age dependent increase in the levels of osteopontin inhibits skeletal muscle regeneration. 2012 Aging (Albany NY)
Alcam Regulates Long-term Hematopoietic Stem Cell Engraftment and Self-Renewal. 2012 Stem Cells