Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Serum-free generation of multipotent mesoderm (kdr(+)) progenitor cells in mouse embryonic stem cells for functional genomics screening. 2012 Curr Protoc Stem Cell Biol
Shh maintains dermal papilla identity and hair morphogenesis via a Noggin-Shh regulatory loop. 2012 Genes Dev
Signal-dependent incorporation of MyoD-BAF60c into Brg1-based SWI/SNF chromatin-remodelling complex. 2012 EMBO J
Signaling defects in iPSC-derived fragile X premutation neurons. 2012 Hum Mol Genet
Single-Cell Analysis of Murine Long-Term Hematopoietic Stem Cells Reveals Distinct Patterns of Gene Expression during Fetal Migration. 2012 PLoS One
Single-cell mass cytometry adapted to measurements of the cell cycle. 2012 Cytometry A
Single-injection HPLC method for rapid analysis of a combination drug delivery system. 2012 AAPS PharmSciTech
Sinus microbiome diversity depletion and Corynebacterium tuberculostearicum enrichment mediates rhinosinusitis. 2012 Sci Transl Med
Site-specific targeting of antibody activity in vivo mediated by disease-associated proteases. 2012 J Control Release
Small Molecule-Mediated TGF-beta Type II Receptor Degradation Promotes Cardiomyogenesis in Embryonic Stem Cells. 2012 Cell Stem Cell
Small molecules greatly improve conversion of human-induced pluripotent stem cells to the neuronal lineage. 2012 Stem Cells Int
Small molecules, big roles – the chemical manipulation of stem cell fate and somatic cell reprogramming. 2012 J Cell Sci
Smyd3 regulates cancer cell phenotypes and catalyzes histone H4 lysine 5 methylation. 2012 Epigenetics
Soft microenvironments promote the early neurogenic differentiation but not self-renewal of human pluripotent stem cells. 2012 Integr Biol (Camb)
Sox1 marks an activated neural stem/progenitor cell in the hippocampus. 2012 Development
SOX2 modulates levels of MITF in normal human melanocytes, and melanoma lines in vitro. 2012 Pigment Cell Melanoma Res
Sphingosine-1-phosphate enhances satellite cell activation in dystrophic muscles through a S1PR2/STAT3 signaling pathway. 2012 PLoS One
SRY-box-containing gene 2 regulation of nuclear receptor tailless (Tlx) transcription in adult neural stem cells. 2012 J Biol Chem
Stage-Specific Cardiomyocyte Differentiation Method for H7 and H9 Human Embryonic Stem Cells. 2012 Stem Cell Rev
Stem cells and modeling of autism spectrum disorders. 2012 Exp Neurol
Stereotaxic surgery for excitotoxic lesion of specific brain areas in the adult rat. 2012 J Vis Exp
Stimulation of histone deacetylase activity by metabolites of intermediary metabolism. 2012 J Biol Chem
Striatal atrophy and dendritic alterations in a knock-in mouse model of Huntington’s disease. 2012 Brain Res Bull
Structural and functional analysis of the transcriptional regulator Rv3066 of Mycobacterium tuberculosis. 2012 Nucleic Acids Res
Structure and mechanism of the tripartite CusCBA heavy-metal efflux complex. 2012 Philos Trans R Soc Lond B Biol Sci
Synthesis and SAR of b-Annulated 1,4-Dihydropyridines Define Cardiomyogenic Compounds as Novel Inhibitors of TGFbeta Signaling. 2012 J Med Chem
TCF/LEFs and Wnt Signaling in the Nucleus. 2012 Cold Spring Harb Perspect Biol
Tet1 controls meiosis by regulating meiotic gene expression. 2012 Nature
Tetrakis(hydroxymethyl) phosphonium chloride as a covalent cross-linking agent for cell encapsulation within protein-based hydrogels. 2012 Biomacromolecules
The anti-CMS technique for genome-wide mapping of 5-hydroxymethylcytosine. 2012 Nat Protoc
The bHLH Repressor Deadpan Regulates the Self-renewal and Specification of Drosophila Larval Neural Stem Cells Independently of Notch. 2012 PLoS One
The Drosophila MI-2 chromatin-remodeling factor regulates higher-order chromatin structure and cohesin dynamics in vivo. 2012 PLoS Genet
The effect of stromal cell-derived factor-1alpha/heparin coating of biodegradable vascular grafts on the recruitment of both endothelial and smooth muscle progenitor cells for accelerated regeneration. 2012 Biomaterials
The emerging functions of the p53-miRNA network in stem cell biology. 2012 Cell Cycle
The expanding world of stem cell modeling of Huntington’s disease: creating tools with a promising future. 2012 Genome Med
The functions of microRNAs in pluripotency and reprogramming. 2012 Nat Cell Biol
The gene expression profiles of induced pluripotent stem cells from individuals with childhood cerebral adrenoleukodystrophy are consistent with proposed mechanisms of pathogenesis. 2012 Stem Cell Res Ther
The genomic stability of induced pluripotent stem cells. 2012 Protein Cell
The GLIB technique for genome-wide mapping of 5-hydroxymethylcytosine. 2012 Nat Protoc
The immunology of neurodegeneration. 2012 J Clin Invest
The LIM protein Ajuba restricts the second heart field progenitor pool by regulating Isl1 activity. 2012 Dev Cell
The little molecules that could: a story about microRNAs in neural stem cells and neurogenesis. 2012 Front Neurosci
The many roads to Rome: induction of neural precursor cells from fibroblasts. 2012 Curr Opin Genet Dev
The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming. 2012 Cell Res
The RB family is required for the self-renewal and survival of human embryonic stem cells. 2012 Nat Commun
The retinoblastoma tumor suppressor and stem cell biology. 2012 Genes Dev
The road to purified hematopoietic stem cell transplants is paved with antibodies. 2012 Curr Opin Immunol
The role of stem cells and progenitors in the genesis of medulloblastoma. 2012 Exp Neurol
The roles of the reprogramming factors Oct4, Sox2 and Klf4 in resetting the somatic cell epigenome during induced pluripotent stem cell generation. 2012 Genome Biol
The SDF-1alpha/CXCR4 axis is required for proliferation and maturation of human fetal pancreatic endocrine progenitor cells. 2012 PLoS One