Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Pre-clinical data supporting immunotherapy for HIV using CMV-HIV-specific CAR T cells with CMV vaccine. 2022 Mol Ther Methods Clin Dev
Preclinical Development and Evaluation of Allogeneic CAR T Cells Targeting CD70 for the Treatment of Renal Cell Carcinoma. 2022 Cancer Res
Primary and metastatic tumors exhibit systems-level differences in dependence on mitochondrial respiratory function. 2022 PLoS Biol
Primary cilia on muscle stem cells are critical to maintain regenerative capacity and are lost during aging. 2022 Nat Commun
Procurement of Deceased Donor Parathyroid Glands With the Aid of Near-infrared Autofluorescence Imaging. 2022 Transplant Direct
Proteomic analysis of the actin cortex in interphase and mitosis. 2022 J Cell Sci
Recent advancements and future requirements in vascularization of cortical organoids. 2022 Front Bioeng Biotechnol
Sexually dimorphic estrogen sensing in skeletal stem cells controls skeletal regeneration. 2022 Nat Commun
Sidestream Smoke Extracts from Harm-Reduction and Conventional Camel Cigarettes Inhibit Osteogenic Differentiation via Oxidative Stress and Differential Activation of intrinsic Apoptotic Pathways. 2022 Antioxidants (Basel)
Spatial organization of heterogeneous immunotherapy target antigen expression in high-grade glioma. 2022 Neoplasia
Spatial transcriptomics using combinatorial fluorescence spectral and lifetime encoding, imaging and analysis. 2022 Nat Commun
Spina Bifida: A Review of the Genetics, Pathophysiology and Emerging Cellular Therapies. 2022 J Dev Biol
Stability and Function of Extracellular Vesicles Derived from Immortalized Human Corneal Stromal Stem Cells: A Proof of Concept Study. 2022 AAPS J
Stem Cell-Derived Islets for Type 2 Diabetes. 2022 Int J Mol Sci
Stromal AR inhibits prostate tumor progression by restraining secretory luminal epithelial cells. 2022 Cell Rep
SZN-413, a FZD4 Agonist, as a Potential Novel Therapeutic for the Treatment of Diabetic Retinopathy. 2022 Transl Vis Sci Technol
Targeting Epigenetic Modifiers of Tumor Plasticity and Cancer Stem Cell Behavior. 2022 Cells
Targeting Immunosuppressive Tumor-Associated Macrophages Using Innate T Cells for Enhanced Antitumor Reactivity. 2022 Cancers (Basel)
Telemedicine Experience of General Surgery Trainees: Impact on Patient Care and Education. 2022 Am Surg
TGFbeta superfamily signaling regulates the state of human stem cell pluripotency and capacity to create well-structured telencephalic organoids. 2022 Stem Cell Reports
The endogenous progenitor response following traumatic brain injury: a target for cell therapy paradigms. 2022 Neural Regen Res
The G209R mutant mouse as a model for human PCSK1 polyendocrinopathy. 2022 Endocrinology
The Prospects for Retinal Organoids in Treatment of Retinal Diseases. 2022 Asia Pac J Ophthalmol (Phila)
The role of BMP4 signaling in trophoblast emergence from pluripotency. 2022 Cell Mol Life Sci
Transplantation of human neural progenitor cells secreting GDNF into the spinal cord of patients with ALS: a phase 1/2a trial. 2022 Nat Med
Treatment of a genetic brain disease by CNS-wide microglia replacement. 2022 Sci Transl Med
Understanding Scarring in the Oral Mucosa. 2022 Adv Wound Care (New Rochelle)
Undifferentiated Induced Pluripotent Stem Cells as a Genetic Model for Nonalcoholic Fatty Liver Disease. 2022 Cell Mol Gastroenterol Hepatol
VE-Cadherin: A Critical Sticking Point for Lymphatic System Maintenance: Role of VE-Cadherin in Lymphatic Maintenance. 2022 Circ Res
A bioinspired and chemically defined alternative to dimethyl sulfoxide for the cryopreservation of human hematopoietic stem cells. 2021 Bone Marrow Transplant
A comparative analysis of deferoxamine treatment modalities for dermal radiation-induced fibrosis. 2021 J Cell Mol Med
A Human Pleiotropic Multiorgan Condition Caused by Deficient Wnt Secretion. 2021 N Engl J Med
A Novel Model of Fetal Spinal Cord Exposure Allowing for Long-Term Postnatal Survival. 2021 Fetal Diagn Ther
Acinar cell clonal expansion in pancreas homeostasis and carcinogenesis. 2021 Nature
Advances in Pancreatic Islet Transplantation Sites for the Treatment of Diabetes. 2021 Front Endocrinol (Lausanne)
Aged skeletal stem cells generate an inflammatory degenerative niche. 2021 Nature
Allogeneic human neural stem cells for improved therapeutic delivery to peritoneal ovarian cancer. 2021 Stem Cell Res Ther
An in vivo Cell-Based Delivery Platform for Zinc Finger Artificial Transcription Factors in Pre-clinical Animal Models. 2021 Front Mol Neurosci
ApoE-Isoform-Dependent SARS-CoV-2 Neurotropism and Cellular Response. 2021 Cell Stem Cell
Application of lung microphysiological systems to COVID-19 modeling and drug discovery: a review. 2021 Biodes Manuf
Assessing Oximetry Response to Chimeric Antigen Receptor T-cell Therapy against Glioma with (19)F MRI in a Murine Model. 2021 Radiol Imaging Cancer
ATF6 is essential for human cone photoreceptor development. 2021 Proc Natl Acad Sci U S A
Autologous Ex Vivo Lentiviral Gene Therapy for Adenosine Deaminase Deficiency. 2021 N Engl J Med
BAF155 methylation drives metastasis by hijacking super-enhancers and subverting anti-tumor immunity. 2021 Nucleic Acids Res
beta-Globin Lentiviral Vectors Have Reduced Titers due to Incomplete Vector RNA Genomes and Lowered Virion Production. 2021 Stem Cell Reports
Biomaterial-based immunoengineering to fight COVID-19 and infectious diseases. 2021 Matter
Biophysical matrix cues from the regenerating niche direct muscle stem cell fate in engineered microenvironments. 2021 Biomaterials
Bioprinting of dual ECM scaffolds encapsulating limbal stem/progenitor cells in active and quiescent statuses. 2021 Biofabrication
Bromodomain containing 9 (BRD9) regulates macrophage inflammatory responses by potentiating glucocorticoid receptor activity. 2021 Proc Natl Acad Sci U S A
CAR T cells with dual targeting of CD19 and CD22 in adult patients with recurrent or refractory B cell malignancies: a phase 1 trial. 2021 Nat Med