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Development of ROR1 CAR-T cells to target cancer stem cells in advanced malignancies

  • Post author:
  • Post published:September 12, 2024
  • Post category:

Translational Candidate Autologous ROR1 CAR-T cell transduced with a lentiviral vector containing scFv (cirmtuzumab) with CD28, CD137, CD3zeta signaling domains Area of Impact ROR1 expressing cancer stem cells in solid…

Continue ReadingDevelopment of ROR1 CAR-T cells to target cancer stem cells in advanced malignancies

IND-Enabling activities for the masked immunocytokine, QXL138AM

  • Post author:
  • Post published:September 12, 2024
  • Post category:

Therapeutic Candidate or Device QXL138AM: A Masked Immunocytokine comprising an anti-CD138 antibody fused to interferon alpha 2b, with a protease cleavable peptide mask Indication QXL138AM is for the treatment of…

Continue ReadingIND-Enabling activities for the masked immunocytokine, QXL138AM
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