Disease Focus: COVID-19

---

Safety “Clinical Trial” of the Cardiac Liability of COVID19 Polytherapy

Combating COVID-19 using human PSC-derived NK cells

Research Objective We propose to generate NK cells with enhanced immunity from gene-edited human PSCs and use the resultant NK cells to kill SARS-CoV-2-infected cells to combat against COVID-19. Impact The use of gene-edited hPSCs as a source for genetically engineered NK cells will allow us to generate effective immunotherapy for COVID-19 that has no […]

Development of COVID-19 Antiviral Therapy Using Human iPSC-Derived Lung Organoids

Research Objective To develop a new therapy for COVID-19 using human iPSC-derived lung organoids that targets SARS-CoV-2 protease known as the virus’ “Achilles Heel” Impact Our work, if successful, will bring a class of new drugs directly targeting viral enzyme and open the door for future COVID therapies. Major Proposed Activities Complete synthesis and testing […]