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Role of the microenvironment in human iPS and NSC fate and tumorigenesis

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  • Post published:September 12, 2026
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Multipotent Neural Stem Cells (NSC) can be derived from adult central nervous system (CNS) tissue, embryonic stem cells (ESC), or iPSC and provide a partially committed cell population that has…

Continue ReadingRole of the microenvironment in human iPS and NSC fate and tumorigenesis

Embryonic-Derived Neural Stem Cells for Treatment of Motor Sequelae following Sub-cortical Stroke

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  • Post published:September 12, 2026
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A stroke kills brain cells by interrupting blood flow. The most common “ischemic stroke” is due to blockage in blood flow from a clot or narrowing in an artery. Brain…

Continue ReadingEmbryonic-Derived Neural Stem Cells for Treatment of Motor Sequelae following Sub-cortical Stroke

Stem Cell-Derived Astrocyte Precursor Transplants in Amyotrophic Lateral Sclerosis

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  • Post published:September 12, 2026
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Amyotrophic lateral sclerosis (ALS), a lethal disease lacking effective treatments, is characterized by the loss of upper and lower motor neurons. 5-10% of ALS is familial, but the majority of…

Continue ReadingStem Cell-Derived Astrocyte Precursor Transplants in Amyotrophic Lateral Sclerosis

Identification and characterization of human ES-derived DA neuronal subtypes

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  • Post published:September 12, 2026
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Parkinson’s disease (PD) is a neurodegenerative movement disorder that affects 1 in 100 people over the age of 60, one million people in the US and six million worldwide. Patients…

Continue ReadingIdentification and characterization of human ES-derived DA neuronal subtypes

Molecular Characterization of hESC and hIPSC-Derived Spinal Motor Neurons

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  • Post published:September 12, 2026
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One of the main objectives of stem cell biology is to create physiologically relevant cell types that can be used to either facilitate the study of or directly treat human…

Continue ReadingMolecular Characterization of hESC and hIPSC-Derived Spinal Motor Neurons

Phase 1/ 2 Study of FRF-001, an AAV-9 Gene Therapy, in Patients with FOXG1 Syndrome (FS)

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  • Post published:September 11, 2026
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Continue ReadingPhase 1/ 2 Study of FRF-001, an AAV-9 Gene Therapy, in Patients with FOXG1 Syndrome (FS)

Personalized antisense oligonucleotide therapy for rare pediatric genetic disease: SCN2A

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  • Post published:September 11, 2026
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Continue ReadingPersonalized antisense oligonucleotide therapy for rare pediatric genetic disease: SCN2A

A Phase 2b Study of the Efficacy of a Novel Pro-Neurogenesis/Pro-Plasticity Drug for Bipolar Depression Using a Precision Psychiatry Approach

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  • Post published:September 11, 2026
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Continue ReadingA Phase 2b Study of the Efficacy of a Novel Pro-Neurogenesis/Pro-Plasticity Drug for Bipolar Depression Using a Precision Psychiatry Approach

Stem Cell-Engineered Off-The-Shelf CAR-NKT Cell Therapy for Multiple Sclerosis

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  • Post published:September 11, 2026
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Continue ReadingStem Cell-Engineered Off-The-Shelf CAR-NKT Cell Therapy for Multiple Sclerosis

Late-stage development of AS-241, an UNC13A Targeting Antisense Oligonucleotide treatment for Amyotrophic Lateral Sclerosis, for IND-enabling studies

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  • Post published:September 11, 2026
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Continue ReadingLate-stage development of AS-241, an UNC13A Targeting Antisense Oligonucleotide treatment for Amyotrophic Lateral Sclerosis, for IND-enabling studies
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