Disease Focus: Neurological Disorders


An hESC-derived hNSC Therapeutic for Huntington’s Disease

Therapeutic Candidate or Device The therapeutic candidate is a human Neural Stem Cell product to prevent or delay disease symptoms for treatment of Huntington's disease (HD). Indication Huntington’s disease, a progressive, degenerative brain disease, typically strikes in midlife with no disease modifying treatment treatments exist. Therapeutic Mechanism Based on our pre-clinical studies, the human neural […]

Intraparenchymal NR1 Stem Cell Therapy for Chronic Subcortical Ischemic Stroke

Therapeutic Candidate or Device A human embryonic derived, non-genetically modified neural stem cell (NR1), originally derived from the Wi-Cell H-9 line. Indication Patients with chronic motor deficits, from 6 months to 5 years after stroke. NR1 cells will be transplanted into the brain near the stroke. Therapeutic Mechanism The proposed therapeutic mechanism of action of […]

Role of Stem Cells on Cognitive Dysfunction after Cancer Therapy

You’d think getting a cancer diagnosis and the subsequent chemo and/or radiation therapy is traumatic enough. But many people receiving cancer therapy also suffer from so-called chemobrain, a condition marked by troubles with memory, attention/concentration, calculations, fine motor skills and other deficits. In this video CIRM grantee and Stanford professor Michelle Monje describes how damage […]

Marina Bershteyn, UCSF – CIRM Stem Cell #SciencePitch

Ian Huggins, UCSD – CIRM Stem Cell #SciencePitch

Anjana Nityanandam, Scripps – CIRM Stem Cell #SciencePitch

Ileana Slavin, Scripps – CIRM Stem Cell #SciencePitch

Jacqueline Ward, UCSD – CIRM Stem Cell #SciencePitch

Roberta Brinton – CIRM Stem Cell #SciencePitch

Wange Lu, USC – CIRM Stem Cell #SciencePitch

Produced by the University of Southern California