Disease Focus: Stroke
A Double-Blind, Controlled Ph 2b Study of the Safety and Efficacy of Modified Stem Cells in Patients with Chronic Motor Deficit from Ischemic Stroke
Therapeutic Candidate or Device Modified adult donor bone marrow-derived mesenchymal stem cells (Modified MSC) Indication Chronic motor deficit secondary to ischemic stroke Therapeutic Mechanism Local intracerebral delivery of Modified MSC adjacent to motor pathways stimulate via a paracrine mechanism neuropoiesis & angiogenesis by the release of FGF-2, other trophic factors & ECM proteins. The net […]
Intraparenchymal NR1 Stem Cell Therapy for Chronic Subcortical Ischemic Stroke
Therapeutic Candidate or Device A human embryonic derived, non-genetically modified neural stem cell (NR1), originally derived from the Wi-Cell H-9 line. Indication Patients with chronic motor deficits, from 6 months to 5 years after stroke. NR1 cells will be transplanted into the brain near the stroke. Therapeutic Mechanism The proposed therapeutic mechanism of action of […]
Facebook Live: Stem Cells and Stroke
CIRM hosted a special ‘Ask the Expert’ Facebook Live event on May 31st, 2018, to discuss the latest progress in the development of stem cell-based treatments for Stroke. Dr. Gary Steinberg, chair of neurosurgery at Stanford University, talked to us about his work in helping reverse the damage caused by a stroke, even for people who […]
Jonathan Lam, UCLA – CIRM Stem Cell #SciencePitch
Pouria Moshayedi, UCLA – CIRM Stem Cell #SciencePitch
Lina Nih, UCLA – CIRM Stem Cell #SciencePitch
Spotlight on Disease Team Awards: Sub-Cortical Stroke – Introduction
Spotlight on Stroke: Introduction Robert Klein, J.D. and Robert Quint, M.D. introduced the speakers for the “Spotlight on Disease Team Awards: Sub-Cortical Stroke,” an educational event presented at the CIRM Governing Board meeting on August 19, 2010. Klein is chair of the CIRM Governing Board. Quint is a cardiologist and a member of the CIRM […]
Spotlight on Disease Team Awards: Sub-Cortical Stroke – Steinberg
Spotlight on Stroke: Steinberg Gary Steinberg, M.D., Ph.D., spoke at the “Spotlight on Disease Team Awards: Sub-Cortical Stroke,” an educational event presented at the CIRM Governing Board meeting on August 19, 2010. Steinberg is the principle investigator for the CIRM Stroke Disease Team. He is also the director of the Stanford Institute for Neuro-Innovation & […]
Spotlight on Disease Team Awards: Sub-Cortical Stroke – Cooper
Spotlight on Stroke: Cooper K. Michael Cooper gave a patient advocate’s perspective on stroke at the “Spotlight on Disease Team Awards: Sub-Cortical Stroke,” an educational event presented at the CIRM Governing Board meeting on August 19, 2010. The CIRM-hosted event was presented in Palo Alto, California at Stanford University.