All CIRM Grants

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Institution Researcher name Grant Type Grant Title Award Value
Stanford University Dr. Gerald R. Crabtree Basic Biology IV Mechanism and Utility of Direct Neuronal Conversion with a MicroRNA-Chromatin Switch $1,392,150
Stanford University Dr. Roel Nusse Basic Biology IV Asymmetric stem cell division oriented by a local self-renewing signal $1,038,600
Buck Institute for Age Research Deepak A Lamba Basic Biology IV 3D Modeling of Retina using Polymer Scaffolds for Understanding Disease Pathogenesis $1,212,553
University of California, San Francisco Dr. Jeremy Reiter Basic Biology IV Modeling disease in human embryonic stem cells using new genetic tools $1,387,800
University of California, San Francisco Barbara Panning Basic Biology IV Investigation of the role of O-GlcNAcylation in SOX2 function during reprogramming $1,260,037
University of California, Davis Dr. Deborah K Lieu Basic Biology IV Induction of Pluripotent Stem Cell-Derived Pacemaking Cells $1,333,689
Stanford University Dr. Howard Y. Chang Basic Biology IV Long noncoding RNAs for pluripotency and cell fate commitment $1,386,627
University of California, San Diego Miles F Wilkinson Basic Biology IV Role of the NMD RNA Decay Pathway in Maintaining the Stem-Like State $1,360,450
Sanford Burnham Prebys Medical Discovery Institute Dr. Huei-sheng Vincent Chen Basic Biology IV Studying Arrhythmogenic Right Ventricular Dysplasia with patient-specific iPS cells $1,579,250
University of California, San Diego Ananda Goldrath Basic Biology IV Mechanisms to protect hESC-derived cells from allogenic immune rejection $1,160,997
City of Hope, Beckman Research Institute Dr. Yanhong Shi Ph.D. Basic Biology IV Modeling Alexander disease using patient-specific induced pluripotent stem cells $1,366,656
Cedars-Sinai Medical Center Eduardo Marbán Basic Biology IV Mechanism of heart regeneration by cardiosphere-derived cells $1,367,604
University of California, San Diego Maike Sander Basic Biology IV Deciphering transcriptional control of pancreatic beta-cell maturation in vitro $1,258,560
University of California, San Diego Dr. David Traver Basic Biology IV DECIPHERING THE INSTRUCTIONS FOR VERTEBRATE HSC SPECIFICATION AND AMPLIFICATION. $1,363,698
University of California, Los Angeles Dr. Owen N Witte M.D. Basic Biology IV Trop2 dependent and independent mechanisms of self-renewal in human cancer stem cells $1,254,960
Stanford University Ben A Barres Basic Biology IV Phenotyping Human Astrocytes in Health and Disease $0
University of California, Berkeley Dr. Robert Tjian Basic Biology IV Transcriptional regulation of pluripotency in human embryonic stem cells $1,220,968
University of California, Los Angeles Dr. Kathrin Plath Dr. Basic Biology IV Understanding the status of the X chromosomes in human ESCs and preimplantation embryos $1,382,400
Gladstone Institutes, J. David Dr. Steve M. Finkbeiner Basic Biology IV Common molecular mechanisms in neurodegenerative diseases using patient based iPSC neurons $1,395,184
Stanford University Alexander Robert Dunn Basic Biology IV Role of mechanical signaling in stem cell self-renewal and differentiation $1,062,998
Stanford University Dr. Anne Brunet Basic Biology IV Energy metabolism and aging pathways in human stem cell reprogramming and differentiation $1,414,044
University of California, San Francisco Dr. Miguel Ramalho-Santos Basic Biology IV Genetic dissection of human cellular reprogramming to pluripotency $1,184,883
Gladstone Institutes, J. David Sheng Ding PhD Basic Biology IV A new paradigm of lineage-specific reprogramming $1,568,395
Stanford University Michael Cleary Basic Biology IV Prostaglandin pathway regulation of self-renwal in hematopoietic and leukemia stem cells $1,244,455
Stanford University Michelle Monje Basic Biology IV Stem Cell Mechanisms Governing Discrete Waves of Gliogenesis in the Childhood Brain $1,264,248
University of California, San Diego Gene Wei-Ming Yeo Basic Biology IV Stem cell models to analyze the role of mutated C9ORF72 in neurodegeneration $1,260,360
Cedars-Sinai Medical Center Professor Clive Niels Svendsen iPSC Consortia Award The HD iPSC Consortium: Repeat Length Dependent Phenotypes for Assay Development $300,000
Stanford University Dr. Joseph C. Wu Disease Team Therapy Development – Research Human Embryonic Stem Cell-Derived Cardiomyocytes for Patients with End Stage Heart Failure $19,060,330
Capricor, Inc Dr. Rachel Ruckdeschel Smith Disease Team Therapy Development – Research Allogeneic Cardiac-Derived Stem Cells for Patients Following a Myocardial Infarction $14,405,857
University of California, Los Angeles Dr. Antoni Ribas MD/PhD Disease Team Therapy Development – Research Genetic Re-programming of Stem Cells to Fight Cancer $14,144,221
University of California, Los Angeles Dr. Stanley Nelson Disease Team Therapy Development – Research Combination Therapy to Enhance Antisense Mediated Exon Skipping for Duchenne Muscular Dystrophy $0
University of California, Irvine Dr. Henry John Klassen Disease Team Therapy Development – Research Retinal progenitor cells for treatment of retinitis pigmentosa $17,144,825
Cedars-Sinai Medical Center Professor Clive Niels Svendsen Disease Team Therapy Development – Research Progenitor Cells Secreting GDNF for the Treatment of ALS $16,168,464
StemCells, Inc. Dr. Alexandra Capela Disease Team Therapy Development – Research Restoration of memory in Alzheimer’s disease: a new paradigm using neural stem cell therapy $8,901,641
Stanford University Dr. Judith A Shizuru Disease Team Therapy Development – Research A monoclonal antibody that depletes blood stem cells and enables chemotherapy free transplants $18,990,683
University of California, Davis Dr. John Laird Disease Team Therapy Development – Research Phase I study of IM Injection of VEGF-Producing MSC for the Treatment of Critical Limb Ischemia $3,728,384
University of California, Davis Dr. Vicki Wheelock Disease Team Therapy Development – Research MSC engineered to produce BDNF for the treatment of Huntington’s disease $8,924,235
StemCells, Inc. Dr. Nobuko Uchida Disease Team Therapy Development – Research Neural stem cell transplantation for chronic cervical spinal cord injury $0
University of California, Davis Nancy E. Lane Disease Team Therapy Development – Research Treatment of non-traumatic osteonecrosis with endogenous Mesenchymal stem cells $18,227,898
Salk Institute for Biological Studies Dr. David R Schubert Early Translational III Stem cell based small molecule therapy for Alzheimer’s disease $1,673,757
City of Hope, Beckman Research Institute Dr. Stephen J Forman Early Translational III Targeting glioma cancer stem cells with receptor-engineered self-renewing memory T cells $5,215,447
Gladstone Institutes, J. David Dr. Deepak Srivastava Early Translational III Direct Cardiac Reprogramming for Heart Regeneration $5,795,871
University of California, San Diego Dr. Lawrence S. B. Goldstein Early Translational III Identifying Drugs for Alzheimer’s Disease with Human Neurons Made From Human IPS cells $1,774,420
University of California, San Diego Dr. Yang Xu Early Translational III Human ES cell based therapy of heart failure without allogenic immune rejection $1,857,600
Stanford University Dr. Joseph C. Wu Early Translational III Heart Repair with Human Tissue Engineered Myocardium $4,395,080
University of California, San Francisco Mort Cowan Early Translational III Gene Correction of Autologous Hematopoietic Stem Cells in Artemis Deficient SCID $3,862,367
Stanford University Professor Helen M. Blau PhD Early Translational III Local Delivery of Rejuvenated Old Muscle Stem Cells to Increase Strength in Aged Patients $1,825,283
University of Southern California Dr. Toshio Miki Early Translational III Generation of hepatic cell from placental stem cell for congenital metabolic disorders $1,750,375
Children’s Hospital of Orange County Dr. Philip H Schwartz Early Translational III Immune-Matched Neural Stem Cell Transplantation for Pediatric Neurodegenerative Disease $4,266,015
University of California, San Francisco Dr. Holger F Willenbring Early Translational III Generation of safe and therapeutically effective human induced hepatocyte-like cells $1,544,170