Our Grants

CIRM provides funding across five key areas: Infrastructure, Education, Discovery Research, Translational Research, and Clinical Research. By supporting projects at every stage of development, from initial discovery to clinical trials, CIRM drives progress in regenerative medicine and accelerates innovative therapies to patients.

Check out our portfolio of awards below.

All CIRM Grants

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Institution Researcher name Grant Type Grant Title Award Value
Stanford University Jeffrey L Goldberg Inception – Discovery Stage Research Projects Embryonic Stem Cells for Corneal Endothelial Degeneration $235,836
University of California, Los Angeles Dr. Owen N Witte M.D. Inception – Discovery Stage Research Projects Identification of stem cell surface markers as potential therapeutic targets for advanced prostate cancer $209,160
University of California, San Diego Professor Alysson R Muotri Inception – Discovery Stage Research Projects Reverse transcriptase inhibitors as a novel therapeutic approach for neurological autoimmune disorders $210,060
University of California, Los Angeles Dr. April Pyle Ph.D. Inception – Discovery Stage Research Projects Novel Platforms to Enhance In Vivo Delivery of Skeletal Muscle Progenitor Cells from Human Pluripotent Stem Cells $230,400
University of California, Los Angeles Dr. Bennett G Novitch Ph.D. Inception – Discovery Stage Research Projects Organoid Modeling of Human Cortical Microcircuits $208,916
Cedars-Sinai Medical Center Professor Clive Niels Svendsen Inception – Discovery Stage Research Projects Blood Brain Barrier (BBB)-on-Chip: Development and validation of a novel iPS-based microfluidic model of the human BBB $241,992
University of California, San Francisco Dr. Holger F Willenbring Inception – Discovery Stage Research Projects Generation of bile duct-competent transplantable human liver organoids $206,460
University of California, Los Angeles Dr. Arjun Deb Inception – Discovery Stage Research Projects Targeting progenitors in scar tissue to reduce chronic scar burden $230,400
University of California, Berkeley Dr. Jacob Ellery Corn Ph.D Inception – Discovery Stage Research Projects Genome editing for causation and reversion of MPN-associated mutations in human hematopoietic stem cells $235,800
Stanford University Dr. Philip Arden Beachy PhD Inception – Discovery Stage Research Projects Curing bladder cancer by replacing corrupted urothelium with differentiated hES cells $210,906
University of California, San Diego Dionicio Siegel Inception – Discovery Stage Research Projects New Methods for the Chemical Expansion of Hematopoietic Stem and Progenitor Cells $232,200
Stanford University Dr. Bertha Chen Inception – Discovery Stage Research Projects Autologous iPSC-based therapy for radiation induced bladder injury $235,836
University of California, Los Angeles Dr. Thomas Carmichael M.D., Ph.D. Inception – Discovery Stage Research Projects iPS-Interneuron Transplantation for Neural Repair after Stroke $229,396
University of California, San Diego Karl Karl J. Wahlin Inception – Discovery Stage Research Projects Microenvironment based optimization of retinal induction using CRISPR-CAS9 reporter pluripotent stem cells as an expandable source of retinal progenitors and photoreceptors. $232,200
University of California, San Francisco Andrew Stephen Brack Inception – Discovery Stage Research Projects Examining the efficacy of GDF11 antibody as a rejuvenator of aged human muscle stem cell capacity and muscle repair . $180,000
Stanford University Dr. Phillip C Yang Inception – Discovery Stage Research Projects Activation of patient-specific endogenous myocardial repair through the exosomes generated from the hypoxic iPSC-derived cardiomyocytes (iCMs). $234,619
Cedars-Sinai Medical Center Linda Cambier Inception – Discovery Stage Research Projects Exosomal Y-RNAs as mediators of bioactivity of cardiac-derived cell therapy $181,063
Stanford University Professor Irving L Weissman MD Tool Translational Research Projects Purification of Human Hematopoietic Stem Cells (HSCs) for Clinical Stem Cell Transplantation $1,347,722
Defined Bioscience, Inc. Steven Douglas Rees Tool Translational Research Projects Development of a low-cost, clinical-grade iPS maintenance medium for enabling stem cell therapy manufacturing $999,848
HEALIOS NA, Inc. Dr. Norihiro Tsuneyoshi Tool Translational Research Projects Generation of human universal donor iPS cells $999,989
University of California, Davis Dr Jan A Nolta Tool Translational Research Projects T-Pure: Peripheral Blood Processing Tool for Point of Care CAR-T Manufacturing $1,217,954
Greenstone Biosciences, Inc. Paul D Pang Tool Translational Research Projects Cell Villages and Clinical Trial in a Dish with Pooled iPSC-CMs for Drug Discovery $1,350,000
Organos, Inc. Samuel Wall Tool Translational Research Projects Human iPSC-derived micro-heart muscles for high-throughput cardiac drug discovery $1,119,382
Stanford University Dr. Joseph C. Wu Tool Translational Research Projects A Novel, Robust and Comprehensive Predictive Tool Using Human Disease-Specific Induced Pluripotent Stem Cells for Preclinical Drug Screening $975,000
University of California, Davis Aijun Wang PhD Medical Device Translational Research Projects Living Synthetic Vascular Grafts with Renewable Endothelium $3,082,579
Cedars-Sinai Medical Center Yuan Yuan Diagnostic Translational Research Projects A Rapid Clinical Digital Patient-derived Organoid to Guide Breast Cancer Treatment Decision $1,535,375
University of California, San Francisco Dr. Steven Mack PhD Diagnostic Translational Research Projects Development of a Noninvasive Prenatal Test for Beta-Hemoglobinopathies for Earlier Stem Cell Therapeutic Interventions $633,014
UCSF Benioff Children’s Hospital Oakland Dr. Henry A. Erlich Ph.D. Diagnostic Translational Research Projects Development of a Noninvasive Prenatal Test for Beta-Hemoglobinopathies for Earlier Stem Cell Therapeutic Interventions $1,074,177
Neurona Therapeutics Dr. Cory R Nicholas Therapeutic Translational Research Projects Development of a universal allogeneic human interneuron cell therapy candidate for the treatment of drug resistant focal epilepsy. $3,828,714
City of Hope, Beckman Research Institute Lei Tian Therapeutic Translational Research Projects Targeting pancreatic cancer with Allogeneic Off-the-Shelf PSCA-CAR NK cells $6,036,000
University of California, Los Angeles Dr. Lili Yang Therapeutic Translational Research Projects Combating Ovarian Cancer with Stem Cell-Engineered Off-The-Shelf CAR-NKT Cell Therapy $5,601,600
Stanford University Natalia Gomez-Ospina Therapeutic Translational Research Projects Toward a Cure for Gaucher Disease Type 1: Autologous Transplantation of Genome Edited Hematopoietic Stem Cells $4,696,296
Replay Holdings, Inc Anthony Conway Therapeutic Translational Research Projects Hypoimmunogenic iPSC-derived TCR-NK cells for oncology $4,107,571
AcuraStem Incorporated Mr. Samuel V. Alworth MS, MBA Therapeutic Translational Research Projects Development of AS-241, an UNC13A Targeting Antisense Oligonucleotide (ASO) Treatment for ALS, for IND-enabling Studies $4,012,325
Axent Biosciences Inc. Abhay Joshi Therapeutic Translational Research Projects A high quality, accessible cell therapy for Parkinson’s Disease produced in a scalable bioreactor system for 3D cell expansion and differentiation $3,999,241
University of California, Los Angeles Dr. Gerald Lipshutz DDS, MD, MS Therapeutic Translational Research Projects Development of a Gene Therapy for Treatment of Guanidinoacetate Methyltransferase Deficiency-Translating In Vivo Proof of Concept to Support a Pre-IND $5,145,825
Ray Therapeutics, INC Paul Bresge Therapeutic Translational Research Projects Optogenetic Therapy for Treatment of Geographic Atrophy $3,998,930
University of California, San Francisco Sarah Monica Knox Therapeutic Translational Research Projects Neurogenic hydrogel stimulation of stem cells to regenerate radiation-damaged salivary glands $2,312,021
Siren Biotechnology, Inc. Dr. Nicole K Paulk Therapeutic Translational Research Projects Development of an AAV gene therapy immunotherapy for the treatment of glioblastoma $3,997,919
Cedars-Sinai Medical Center Dr. Ahmed Gamal Ibrahim Therapeutic Translational Research Projects Noncoding RNA drug TY1 as a therapeutic candidate for scleroderma and systemic sclerosis $2,590,224
University of California, San Diego Dr Karen Christman Therapeutic Translational Research Projects Pro-regenerative infusible ECM biomaterial for treating acute myocardial infarction $4,353,438
University of California, Los Angeles Zulema Romero Garcia Therapeutic Translational Research Projects Adenine Base Editing for Autologous Hematopoietic Stem Cell Gene Therapy of CD3δ SCID $5,966,928
University of California, Los Angeles Dr. Donald B Kohn Therapeutic Translational Research Projects Hematopoietic Stem Cell Gene Editing for X-linked Agammaglobulinemia (XLA) $4,309,973
University of California, San Diego Dr. Eric D. Adler MD Therapeutic Translational Research Projects Ex Vivo Modified Hematopoietic Stem Cells to Treat Danon Disease $5,180,389
University of California, Los Angeles Dr. Gerald Lipshutz DDS, MD, MS Therapeutic Translational Research Projects Development of a Gene Therapy for the Treatment of Arginase Deficiency – Translating from Proof of Concept to Support Pre-IND Meeting $5,266,504
City of Hope, Beckman Research Institute Dr Michael A. Caligiuri Therapeutic Translational Research Projects Targeting multiple myeloma with BCMA-CAR NK cells expressing a GPRC5D-NKG2D bispecific antibody $6,036,001
University of California, Los Angeles Anthony J Aldave Therapeutic Translational Research Projects AAV Gene Therapy for Treating Congenital Hereditary Endothelial Dystrophy associated with Biallelic SLC4A11 Mutations $4,338,166
ImmunoVec Luke Riggan Therapeutic Translational Research Projects Hematopoietic Stem Cell Gene Therapy for Wiskott Aldrich Syndrome $3,999,899
BrainXell Therapeutics Maria Daniela Cirnaru Therapeutic Translational Research Projects Development of Autologous Cell Replacement Therapy for Parkinson’s Disease: Path to Personalized Treatment $3,841,110
University of California, Los Angeles Dr. Sophie X Deng Therapeutic Translational Research Projects Extracellular Vesicle-Based Therapy for Corneal Scars $5,779,276

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