CIRM provides funding across five key areas: Infrastructure, Education, Discovery Research, Translational Research, and Clinical Research. By supporting projects at every stage of development, from initial discovery to clinical trials, CIRM drives progress in regenerative medicine and accelerates innovative therapies to patients.
Check out our portfolio of awards below. Click here to see a list of People We’ve Funded. Click here to see a list of our Funded Institutions.
All CIRM Grants
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| Institution |
Researcher name |
Grant Type |
Grant Title |
Award Value |
| University of California, Los Angeles |
Dr. Donald B. Kohn PhD |
Clinical Trial Stage Projects |
Efficacy and safety of cryopreserved autologous CD34+ HSC transduced with EFS lentiviral vector encoding for human ADA gene in ADA-SCID subjects |
$5,827,000 |
| Orchard Therapeutics plc |
Leslie Meltzer |
Clinical Trial Stage Projects |
Efficacy and safety of cryopreserved autologous CD34+ HSC transduced with EFS lentiviral vector encoding for human ADA gene in ADA-SCID subjects |
$2,638,745 |
| University of California, Los Angeles |
Dr. Donald B. Kohn PhD |
Clinical Trial Stage Projects |
Efficacy and safety of cryopreserved autologous CD34+ HSC transduced with EFS lentiviral vector encoding for human ADA gene in ADA-SCID subjects |
$10,156,925 |
| Cedars-Sinai Medical Center |
Professor Clive Niels Svendsen |
Clinical Trial Stage Projects |
Human Neural Progenitors Secreting Glial Cell Line-Derived Neurotrophic Factor (CNS10-NPC-GDNF) for the Treatment of Amyotrophic Lateral Sclerosis |
$6,154,067 |
| University of California, San Francisco |
Dr. Tippi C. MacKenzie |
Clinical Trial Stage Projects |
In Utero Hematopoietic Stem Cell Transplantation For The Treatment Of Fetuses With Alpha Thalassemia Major |
$9,350,000 |
| Humacyte, Inc. |
Jeffrey Lawson |
Clinical Trial Stage Projects |
A Human Acellular Vessel in Patients Needing Renal Replacement Therapy: A Comparison with ePTFE Grafts as Conduits for Hemodialysis (HUMANITY) |
$7,625,000 |
| Capricor, Inc |
Dr. Linda Marban |
Clinical Trial Stage Projects |
Allogeneic Cardiosphere-Derived Cells for Duchenne Muscular Dystrophy Cardiomyopathy |
$3,376,259 |
| University of California, Davis |
Dr Mehrdad Abedi |
Clinical Trial Stage Projects |
Stem Cell Gene Therapy for HIV Mediated by Lentivector Transduced, Pre-selected CD34+ Cells in AIDS lymphoma patients |
$8,414,265 |
| ImmunoCellular Therapeutics |
Anthony J. Gringeri |
Clinical Trial Stage Projects |
A Phase III randomized double-blind, controlled study of ICT 107 with maintenance temozolomide (TMZ) in newly diagnosed glioblastoma following resection and concomitant TMZ chemoradiotherapy |
$5,391,016 |
| Caladrius Biosciences |
Robert Dillman |
Clinical Trial Stage Projects |
Tumor stem cell-targeted immunotherapy for metastatic melanoma –a randomized phase 3 clinical trial. |
$3,000,000 |
| University of California, Los Angeles |
Dr. Donald B. Kohn PhD |
Clinical Trial Stage Projects |
A Phase I/II, Non Randomized, Multicenter, Open-Label Study of G1XCGD (Lentiviral Vector Transduced CD34+ Cells) in Patients With X-Linked Chronic Granulomatous Disease |
$7,083,364 |
| Cure Rare Disease |
Dr. Susan Perlman |
Late Stage Preclinical Projects |
Advancing a novel antisense oligonucleotide for the treatment of SCA3, a devastating neurodegenerative disease |
$5,692,538 |
| University of California, Davis |
Dr. Joseph S Anderson |
Late Stage Preclinical Projects |
Expression of Ube3a by the hematopoietic system for the treatment of Angelman syndrome |
$4,487,656 |
| Rejuvenate Bio |
Noah Davidsohn |
Late Stage Preclinical Projects |
Novel Gene Therapy Targeting Multiple Pathological Drivers of Desmoplakin Associated Arrhythmogenic Cardiomyopathy |
$4,000,000 |
| Amplo Biotechnology Inc |
Patricio Sepulveda |
Late Stage Preclinical Projects |
Targeted DOK7 gene therapy for Congenital Myasthenic Syndromes |
$2,894,305 |
| University of California, Los Angeles |
Dr. Arjun Deb |
Late Stage Preclinical Projects |
Development of a therapeutic monoclonal antibody for the treatment of myocardial infarction and heart failure |
$5,999,998 |
| University of California, San Diego |
Mark H Tuszynski |
Late Stage Preclinical Projects |
Human Embryonic Stem Cell-Derived Neural Stem Cells for Severe Spinal Cord Injury (SCI) |
$6,000,000 |
| Children’s Hospital of Los Angeles |
Shahab Asgharzadeh |
Late Stage Preclinical Projects |
Chimeric TGFB Signaling Receptor (CTSR) Enabled Anti-B7H3 CAR T-cell Therapy in Children and AYA with Recurrent Solid Tumors |
$6,000,000 |
| Elpida Therapeutics |
Mr Terry Pirovolakis |
Late Stage Preclinical Projects |
Pre-Clinical To Clinical Gene Therapy Development For CMT4J |
$3,930,964 |
| University of California, San Francisco |
Thomas Martin |
Late Stage Preclinical Projects |
A 1XX-enhanced and fully non-viral BCMA CAR T cell therapy for Relapsed and Refractory Multiple Myeloma (UCCT-BCMA-1) |
$4,585,501 |
| AcuraStem Incorporated |
Mr. Samuel V. Alworth MS, MBA |
Late Stage Preclinical Projects |
Manufacturing of AS-202, an Antisense oligonucleotides for a Phase 1/2 Clinical Trial for Amyotrophic Lateral Sclerosis |
$0 |
| Cedars-Sinai Medical Center |
Dr. Eugenio Cingolani |
Late Stage Preclinical Projects |
Extracellular Vesicles for Ventricular Tachycardia |
$5,999,441 |
| City of Hope, Beckman Research Institute |
Prof. Karen S Aboody M.D. |
Late Stage Preclinical Projects |
Neural stem cell delivered CRAd-S-pk7 oncolytic viro-immunotherapy for ovarian cancer |
$5,314,547 |
| Tr1X Inc. |
Dr. Maria Grazia Roncarolo |
Late Stage Preclinical Projects |
TRX103 for prevention of GvHD in patients receiving HLA mismatched related or unrelated allogeneic HSCT for the treatment of hematologic malignancies. |
$4,000,000 |
| Mahzi Therapeutics |
Dr. Yael Weiss |
Late Stage Preclinical Projects |
Development of a Gene Therapy for the Treatment of WWOX related epileptic encephalopathy (WOREE) |
$4,000,000 |
| University of California, Davis |
Dr Mehrdad Abedi |
Late Stage Preclinical Projects |
Superior forward-oriented b-globin vector for treating Sickle Cell Disease |
$4,598,398 |
| University of Southern California |
Dr. Mark S Humayun |
Late Stage Preclinical Projects |
IND-enabling program for PRPE-SF, the secretome from polarized stem cell-derived RPE cells, for the treatment of dry-age related macular degeneration |
$5,993,562 |
| Stanford University |
Dr. Matthew H Porteus |
Late Stage Preclinical Projects |
Autologous Gene Corrected Sinus Basal Cells to Treat Serious Cystic Fibrosis Sinus Disease |
$6,000,000 |
| University of California, Irvine |
Kyriacos A Athanasiou |
Late Stage Preclinical Projects |
Treatment of the TMJ disc complex |
$6,000,000 |
| Aspera Biomedicines, Inc. |
Catriona Jamieson |
Late Stage Preclinical Projects |
Cancer Stem Cell Interception with Rebecsinib: A First-in-Class ADAR1 Inhibitor |
$3,200,000 |
| University of California, Los Angeles |
Dr. Jerome A. Zack Ph.D. |
Late Stage Preclinical Projects |
Clinical Translation of Autologous Regenerative Pluripotent Stem Cell Therapy for Blindness |
$6,000,000 |
| Kenai Therapeutics |
Howard J Federoff |
Late Stage Preclinical Projects |
Allogeneic iPSC derived Dopaminergic Drug Product for Parkinson’s disease |
$4,000,000 |
| Rampart Bioscience |
Jeffrey Bartlett |
Late Stage Preclinical Projects |
Ex vivo Engineering of Autologous Hematopoietic Stem Cells for the Treatment of Hypophosphatasia |
$3,999,980 |
| Nammi Therapeutics, Inc. |
Dr. David R Stover |
Late Stage Preclinical Projects |
IND-Enabling activities for the masked immunocytokine, QXL138AM |
$3,999,113 |
| Calidi Biotherapeutics, Inc. |
8587949607 Boris Minev |
Late Stage Preclinical Projects |
Allogeneic mesenchymal stem cells loaded with oncolytic virus for cancer treatment |
$3,111,467 |
| Ossium Health, Inc. |
Dr. Brian Johnstone |
Late Stage Preclinical Projects |
Development of OSSM-007, cryopreserved interferon-gamma primed allogeneic MSCs, for treatment of steroid refractory acute graft versus host disease |
$3,457,858 |
| University of California, Davis |
Dr. Joseph S Anderson |
Late Stage Preclinical Projects |
Hematopoetic stem cell gene therapy for the treatment of Tay-Sachs disease |
$4,048,253 |
| Stanford University |
Natalia Gomez-Ospina |
Late Stage Preclinical Projects |
Genome Editing of Autologous Hematopoietic Stem Cells to Treat Severe Mucopolysaccharidosis type 1 (Hurler Syndrome) |
$5,444,353 |
| University of California, San Francisco |
Dr. Karin Lindgren Gaensler |
Late Stage Preclinical Projects |
Development of TriLeukeVax, an Engineered Autologous Leukemia Vaccine for Stimulating Cytolytic Immune Responses to Residual Leukemic Stem Cells |
$6,000,000 |
| ImmunoVec |
Dr. Ryan L. Wong |
Late Stage Preclinical Projects |
Hematopoietic Stem Cell Gene Therapy for XCGD |
$3,999,959 |
| University of California, Los Angeles |
Dr. Antoni Ribas MD/PhD |
Late Stage Preclinical Projects |
Skin regeneration and wound healing with a topical BRAF inhibitor |
$5,005,126 |
| University of Southern California |
Dr. Denis A Evseenko Dr. |
Late Stage Preclinical Projects |
Plurocart: a novel stem cell-based implant for articular cartilage restoration |
$5,999,782 |
| University of California, San Diego |
Thomas J Kipps |
Late Stage Preclinical Projects |
Late Stage Pre-Clinical Development of a Cirmtuzumab Based CAR T-cell for the Treatment of ROR1+ Hematological Malignancies |
$1,630,360 |
| Stanford University |
Dr. Rosa Bacchetta |
Late Stage Preclinical Projects |
IND-enabling activities for a Phase 1 Study of Autologous CD4LVFOXP3 T Cells in Subjects with IPEX Syndrome |
$5,002,496 |
| University of California, San Francisco |
Mark C. Walters M.D. |
Late Stage Preclinical Projects |
Curing Sickle cell Disease with CRISPR-Cas9 genome editing |
$2,242,805 |
| University of California, Davis |
Dr. Diana L. Farmer |
Late Stage Preclinical Projects |
Placental Mesenchymal Stem Cell Augmentation of Fetal Myelomeningocele Repair |
$5,615,207 |
| Ankasa Regenerative Therapeutics, Inc. |
Ying Zhu |
Late Stage Preclinical Projects |
IND-enabling development of ART352-L, an endogenous stem cell reactivation therapy to enhance bone healing in the elderly |
$3,987,693 |
| City of Hope, Beckman Research Institute |
Xiuli Wang |
Late Stage Preclinical Projects |
CMV-specific T cells expressing anti-HIV CAR and CMV vaccine boost as immunotherapy for HIV/AIDS |
$3,812,797 |
| University of California, San Francisco |
Dr. Krystof Bankiewicz |
Late Stage Preclinical Projects |
MRI Guided Delivery of Neural Progenitor Cells Secreting GDNF for the Treatment of Parkinson’s disease |
$5,757,078 |
| Poseida Therapeutics, Inc. |
Devon J Shedlock |
Late Stage Preclinical Projects |
Late-Stage Preclinical Study of CAR-T Memory Stem Cells Targeting PSMA (P-PSMA-101) for the Treatment of Castrate-Resistant Metastatic Prostate Cancer |
$3,992,090 |
