Our Grants

CIRM provides funding across five key areas: Infrastructure, Education, Discovery Research, Translational Research, and Clinical Research. By supporting projects at every stage of development, from initial discovery to clinical trials, CIRM drives progress in regenerative medicine and accelerates innovative therapies to patients.

Check out our portfolio of awards below.

All CIRM Grants

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Institution Researcher name Grant Type Grant Title Award Value
University of California, Los Angeles Dr. Richard Joseph Pietras Quest – Discovery Stage Research Projects Reversal of dysregulated myelopoiesis in breast cancers and cancer stem cells to boost antitumor immunotherapy $2,327,680
Greenstone Biosciences, Inc. Paul D Pang Quest – Discovery Stage Research Projects Drug Discovery for Duchenne Muscular Dystrophy Using Patient-Derived Human iPSCs $675,000
University of California, Berkeley Mr. Fyodor Urnov Quest – Discovery Stage Research Projects A Treatment for Artemis-deficient Severe Combined Immunodeficiency using Non-Viral CRISPR-driven Safe Harbor Transgenesis in Hematopoietic Stem Cells $1,809,372
University of California, Davis Aijun Wang PhD Quest – Discovery Stage Research Projects In Utero Treatment of Duchenne Muscular Dystrophy with Non-viral Gene Editing $2,035,544
Rubedo Life Sciences Inc. Marco Quarta Quest – Discovery Stage Research Projects Pharmacological regenerative treatment of idiopathic pulmonary fibrosis targeting the senescent niche of lung progenitor cells. $1,450,876
University of California, Los Angeles Dr. Gerald Lipshutz Quest – Discovery Stage Research Projects Gene Therapy for SLC6A8 Creatine Transporter Disorder $2,296,920
University of California, Los Angeles Frank Pajonk Quest – Discovery Stage Research Projects Development of novel small molecules against cancer stem cells in solid cancers $2,340,000
Scripps Health Dr. Darryl D. D’Lima Quest – Discovery Stage Research Projects Pluripotent Stem Cells for Tendon Tissue Engineering $2,734,163
Cedars-Sinai Medical Center Dmitriy Sheyn Quest – Discovery Stage Research Projects Microgel encapsulated iPSC-derived notochordal cells to treat intervertebral disc degeneration and low back pain $2,020,166
Lundquist Institute for Biomedical Innovation at Harbor – UCLA Medical Center Dr. Michelina Iacovino PhD Quest – Discovery Stage Research Projects A Novel Therapy for Sanfilippo B $2,297,884
University of California, Berkeley 5106433559 Kevin E. Healy Quest – Discovery Stage Research Projects Novel Lipid Nanoparticles for Enhancing eNOS Synthesis for Cardioprotection Post Myocardial Infarction $2,060,248
BrainXell Therapeutics Matthew Goodus Quest – Discovery Stage Research Projects Autologous stem cell-derived interneuron cell therapy for spinal cord injury (SCI) $2,025,000
University of California, San Diego Professor Alysson R Muotri Quest – Discovery Stage Research Projects A treatment for Rett syndrome using glial-restricted neural progenitor cells $1,402,240
Gladstone Institutes, J. David Dr. Deepak Srivastava Quest – Discovery Stage Research Projects Modified RNA-Based Gene Therapy for Cardiac Regeneration Through Cardiomyocyte Proliferation $1,565,784
The Scintillon Institute Brian Lawson Quest – Discovery Stage Research Projects An hematopoietic stem-cell-based approach to treat HIV employing CAR T cells and anti-HIV broadly neutralizing antibodies. $1,143,600
University of California, Irvine Dr. Michael Demetriou Quest – Discovery Stage Research Projects CAR T cells targeting abnormal N-glycans for the treatment of refractory/metastatic solid cancers $1,414,800
University of California, Los Angeles Dr. Lili Yang Quest – Discovery Stage Research Projects Combating Ovarian Cancer Using Stem Cell-Engineered Off-The-Shelf CAR-iNKT Cells $1,404,000
Minutia, Inc. Katy Digovich Quest – Discovery Stage Research Projects Bioengineering human stem cell-derived beta cell organoids to monitor cell health in real time and improve therapeutic outcomes in patients $1,198,550
Nanotools Bioscience Dr. Alex Savtchenko PhD Quest – Discovery Stage Research Projects Enabling non-genetic activity-driven maturation of iPSC-derived neurons $675,000
University of California, Los Angeles Dr. Xian-Jie Yang Quest – Discovery Stage Research Projects Developing gene therapy for dominant optic atrophy using human pluripotent stem cell-derived retinal organoid disease models $1,345,691
University of California, San Diego Dr. Joseph G. Gleeson Quest – Discovery Stage Research Projects Novel antisense therapy to treat genetic forms of neurodevelopmental disease. $1,180,654
Scripps Research Institute Stuart A Lipton Quest – Discovery Stage Research Projects Drug Development of Inhibitors of Inflammation Using Human iPSC-Derived Microglia (hiMG) $1,658,123
University of California, Los Angeles Dr Dinesh S Rao Quest – Discovery Stage Research Projects Novel methods to eliminate cancer stem cells $1,384,347
University of California, San Diego Dr. Michael Karin Quest – Discovery Stage Research Projects Targeting pancreatic cancer stem cells with DDR1 antibodies. $1,425,600
Cedars-Sinai Medical Center Dr. Robert Barrett Quest – Discovery Stage Research Projects A new precision medicine based iPSC-derived model to study personalized intestinal fibrosis treatments in pediatric patients with Crohn’s disease $776,340
Scripps Research Institute Dr Michael J Bollong Quest – Discovery Stage Research Projects Therapeutics to overcome the differentiation roadblock in Myelodysplastic Syndrome (MDS) $1,244,160
University of California, Davis Dr. Kyle D Fink PhD Quest – Discovery Stage Research Projects AAV-dCas9 Epigenetic Editing for CDKL5 Deficiency Disorder $1,429,378
University of California, Los Angeles Dr. Caroline Y. Kuo Quest – Discovery Stage Research Projects Defining the Optimal Gene Therapy Approach of Human Hematopoietic Stem Cells for the Treatment of Dedicator of Cytokinesis 8 (DOCK8) Deficiency $1,386,232
University of California, Los Angeles Dr. Donald B. Kohn PhD Quest – Discovery Stage Research Projects Hematopoietic Stem Cell Gene Therapy for Alpha Thalassemia $1,177,739
Stanford University Dr. Judith A Shizuru Quest – Discovery Stage Research Projects Targeted Immunotherapy-Based Blood Stem Cell Transplantation $1,341,910
Tenaya Therapeutics, Inc. Karl N Doerner Quest – Discovery Stage Research Projects Cardiac Reprogramming Gene Therapy for Post-Myocardial Infarction Heart Failure $1,017,000
Intact Therapeutics, Inc. Jeffrey Linhardt Quest – Discovery Stage Research Projects Modulation of oral epithelium stem cells by RSpo1 for the prevention and treatment of oral mucositis $942,050
Cytonus Therapeutics, Inc. Dr. Edward Filardo Quest – Discovery Stage Research Projects Development of a novel stem-cell based carrier for intravenous delivery of oncolytic viruses $899,342
Salk Institute for Biological Studies Ronald Mark Evans Quest – Discovery Stage Research Projects Extending Immune-Evasive Human Islet-Like Organoids (HILOs) Survival and Function as a Cure for T1D $1,523,285
Stanford University Ansuman Satpathy Quest – Discovery Stage Research Projects Preclinical development of an exhaustion-resistant CAR-T stem cell for cancer immunotherapy $1,420,200
Stanford University Dr. Bertha Chen Quest – Discovery Stage Research Projects iPSC-derived smooth muscle cell progenitor conditioned medium for treatment of pelvic organ prolapse $1,420,200
University of California, San Francisco Brian Feeley Quest – Discovery Stage Research Projects Matrix Assisted Cell Transplantation of Promyogenic Fibroadipogenic Progenitor (FAP) Stem Cells $1,179,478
University of California, Los Angeles Prof. Song Li Quest – Discovery Stage Research Projects iPSC Extracellular Vesicles for Diabetes Therapy $1,354,928
Scripps Health Dr. Darryl D. D’Lima Quest – Discovery Stage Research Projects Meniscal Repair and Regeneration $1,361,775
The Stone Research Foundation for Sports Medicine and Arthritis Dr. Kevin Stone Quest – Discovery Stage Research Projects A Novel Therapy for Articular Cartilage Autologous Cellular Repair by Paste Grafting $1,180,309
University of California, San Diego Gene Wei-Ming Yeo Quest – Discovery Stage Research Projects RNA-directed therapy for Huntington’s disease $1,253,110
University of California, Irvine Dr. Mathew Mark Blurton-Jones Quest – Discovery Stage Research Projects Transplantation of genetically corrected iPSC-microglia for the treatment of Sanfilippo Syndrome (MPSIIIA) $1,083,379
University of California, San Francisco Dr. Julie Deane Saba Quest – Discovery Stage Research Projects Providing a cure for sphingosine phosphate lyase insufficiency syndrome (SPLIS) through adeno-associated viral mediated SGPL1 gene therapy $1,463,400
Scripps Research Institute Luke L Lairson Quest – Discovery Stage Research Projects Improving the efficacy and tolerability of clinically validated remyelination-inducing molecules using developable combinations of approved drugs $1,554,126
University of California, San Francisco Dr Julia Carnevale Quest – Discovery Stage Research Projects Generating deeper and more durable BCMA CAR T cell responses in Multiple Myeloma through non-viral knockin/knockout multiplexed genome engineering $1,463,368
Stanford University Dr. Sarah C Heilshorn Quest – Discovery Stage Research Projects Injectable, autologous iPSC-based therapy for spinal cord injury $789,000
Navega Therapeutics Ana Maria Moreno Quest – Discovery Stage Research Projects Optimization of a gene therapy for inherited erythromelalgia in iPSC-derived neurons $1,157,313
Cedars-Sinai Medical Center Dr Eduardo Marban Quest – Discovery Stage Research Projects New noncoding RNA chemical entity for heart failure with preserved ejection fraction. $1,397,412
Stanford University Dr. Stanley Qi Quest – Discovery Stage Research Projects A novel hybrid CRISPR tool for gene network perturbation and hiPSC engineering $704,661
University of California, San Diego Ziwei Huang Quest – Discovery Stage Research Projects Development of a new therapeutic for directing target specific stem cell migration and treatment $1,129,512
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