CIRM provides funding across five key areas: Infrastructure, Education, Discovery Research, Translational Research, and Clinical Research. By supporting projects at every stage of development, from initial discovery to clinical trials, CIRM drives progress in regenerative medicine and accelerates innovative therapies to patients.
Check out our portfolio of awards below. Click here to see a list of People We’ve Funded. Click here to see a list of our Funded Institutions.
All CIRM Grants
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| Institution |
Researcher name |
Grant Type |
Grant Title |
Award Value |
| Neurona Therapeutics |
Dr. Cory R Nicholas |
Clinical Trial Stage Projects |
Inhibitory Interneuron Cell Therapy (NRTX-1001) for the Treatment of Drug-resistant Bilateral Temporal Lobe Epilepsy |
$13,999,983 |
| University of California, San Francisco |
Mort Cowan |
Clinical Trial Stage Projects |
Gene Therapy for Artemis-Deficient Severe Combined Immunodeficiency Using a Self-Inactivating Lentiviral Vector |
$14,999,999 |
| Tenaya Therapeutics, Inc. |
Dr. Matthew Pollman |
Clinical Trial Stage Projects |
Phase 1b Study of TN-401 in Adults with PKP2 Mutation-associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) |
$8,000,000 |
| Tr1X Inc. |
Dr. Maria Grazia Roncarolo |
Clinical Trial Stage Projects |
TRX103 for prevention of GvHD in patients receiving HLA mismatched HSCT for the treatment of hematologic malignancies |
$8,000,000 |
| University of California, Los Angeles |
Dr. Donald B. Kohn PhD |
Clinical Trial Stage Projects |
Efficacy and safety of cryopreserved autologous CD34+ HSC transduced with EFS-ADA lentiviral vector encoding for human ADA gene in ADA-SCID subjects |
$14,325,181 |
| Fate Therapeutics, Inc. |
Bob Valamehr |
Clinical Trial Stage Projects |
A Phase 1 Study of FT819 in Participants with Moderate to Severe Active Systemic Lupus Erythematosus |
$7,934,448 |
| Senti Biosciences, Inc. |
Rochelle Emery |
Clinical Trial Stage Projects |
Selective, Off-the-Shelf Logic Gated CAR NK Cell Therapy Targeting CD33 and/or FLT3 Expressing Hematologic Malignancies |
$8,000,000 |
| ImmPACT-Bio, Inc. |
DR Jonathan Benjamin |
Clinical Trial Stage Projects |
A phase 1/2 study to evaluate a bispecific CD19/CD20-directed CAR T cell, in refractory lupus nephritis and systemic lupus erythematosus |
$841,214 |
| Nexcella, Inc. |
Ilya Rachman MD PhD |
Clinical Trial Stage Projects |
Autologous BCMA CAR-T Cells for the Treatment of Relapsed Refractory Light Chain Amyloidosis |
$7,999,467 |
| University of California, San Francisco |
Dr. Hideho Okada |
Clinical Trial Stage Projects |
Phase 1 Study of Autologous E-SYNC T Cells in Adult Participants with EGFRvIII+ Glioblastoma |
$10,927,618 |
| Aspen Neuroscience |
Dr. Edward Wirth III |
Clinical Trial Stage Projects |
Phase 1/2a Dose Escalation Study of ANPD001 in Sporadic Parkinson Disease |
$8,000,000 |
| Alto Neuroscience |
Amit Etkin |
Clinical Trial Stage Projects |
A Phase 2b Study of the Efficacy of a Novel Pro-Neurogenesis/Pro-Plasticity Drug for Bipolar Depression Using a Precision Psychiatry Approach |
$0 |
| Allogene Therapeutics |
Dr. John Le Gall |
Clinical Trial Stage Projects |
A PHASE 1B STUDY EVALUATING THE SAFETY AND EFFICACY OF AN ALLOGENEIC CELL THERAPY IN SUBJECTS WITH CLEAR CELL RENAL CELL CARCINOMA (ccRCC) |
$15,000,000 |
| University of California, San Francisco |
Noriyuki Kasahara |
Clinical Trial Stage Projects |
A Phase I/IIa Study to Evaluate the Efficacy of Toca 511/Toca FC with Standard of Care Therapy in Newly Diagnosed High Grade Glioma |
$11,807,220 |
| Luxa Biotechnology |
Dr. Jeffrey H Stern |
Clinical Trial Stage Projects |
RPESC-RPE-4W Therapy for dry Age-related Macular Degeneration |
$4,009,675 |
| Rocket Pharmaceuticals, Inc. |
Dr. Jonathan Schwartz |
Clinical Trial Stage Projects |
A Phase 2 Study Evaluating the Efficacy and Safety of IV Administered rAAV9 Vector Containing RP-A501 in Male Patients with Danon Disease |
$5,808,735 |
| University of California, Davis |
Dr. Diana L. Farmer |
Clinical Trial Stage Projects |
The CuRe Trial: Cellular Therapy for In Utero Repair of Myelomeningocele |
$8,996,477 |
| Stanford University |
Dr. Reena Parada Thomas |
Clinical Trial Stage Projects |
Phase I Trial of Locoregionally Delivered Autologous B7-H3 CAR T Cells (B7-H3CART) in Adults with Recurrent Glioblastoma Multiforme |
$11,999,991 |
| City of Hope, Beckman Research Institute |
Elizabeth Budde |
Clinical Trial Stage Projects |
Phase I Study of Chimeric Antigen Receptor Engineered T Cells targeting CD33 for the Treatment of Relapsed/Refractory Acute Myeloid Leukemia |
$11,983,547 |
| University of California, San Diego |
Prof. Olivia Kim-McManus |
Clinical Trial Stage Projects |
Personalized antisense oligonucleotide therapy for rare pediatric genetic disease: SCN2A |
$960,713 |
| Stanford University |
Anusha Kalbasi |
Clinical Trial Stage Projects |
Stem-Derived IL13Ra2 Chimeric Antigen Receptor T cells for Patients with Melanoma and Advanced Solid Tumors |
$10,211,085 |
| University of California, Los Angeles |
Dr. Jeffrey L Veale |
Clinical Trial Stage Projects |
The UCLA Delayed Immunological Tolerance after Kidney Transplantation Program |
$6,717,608 |
| Regenerative Patch Technologies LLC |
Dr Jane S Lebkowski |
Clinical Trial Stage Projects |
A Phase 2b, Randomized, Assessor-Masked Clinical Trial to Assess the Safety and Efficacy of the CPCB-RPE1 Implant in Subjects with Geographic Atrophy |
$12,373,748 |
| City of Hope, Beckman Research Institute |
Dr. Angelo Manuel Almeida Cardoso Ph.D., MD |
Clinical Trial Stage Projects |
Evaluation of Safety and Feasibility of Cytomegalovirus-Specific, Anti-HIV Chimeric Antigen Receptor (CMV/HIV-CAR) T Cells in People with HIV |
$11,299,976 |
| Combangio, Inc. |
R. Kim Brazzell |
Clinical Trial Stage Projects |
Phase 2b Clinical Study of KPI-012 Topical Ophthalmic Human Mesenchymal Stem Cell Secretome for the Treatment of Persistent Corneal Epithelial Defect |
$15,000,000 |
| Immusoft Corporation |
Dr Robert Hayes |
Clinical Trial Stage Projects |
A Phase I Open Label Study to Evaluate the Safety and Tolerability of ISP-001 in Patients with Mucopolysaccharidosis Type 1 |
$8,000,000 |
| Eureka Therapeutics, Inc. |
Pei Wang |
Clinical Trial Stage Projects |
Autologous ARTEMIS® T Cells to Treat Refractory/Relapsed Pediatric Liver Cancer |
$10,600,072 |
| Stanford University |
Dr. Matthew H Porteus |
Clinical Trial Stage Projects |
Reduced intensity conditioning with JSP191 prior to TCRαβ+ T-cell/CD19+ B-cell depleted hematopoietic stem cell transplant for Fanconi Anemia patients |
$10,642,420 |
| Angiocrine Bioscience, Inc. |
Dr. Paul Finnegan |
Clinical Trial Stage Projects |
AB-205-301 Phase 3 Trial and Related Activities to Support Clinical Development of AB-205 |
$10,930,014 |
| Genascence Corporation |
Dr. Thomas W Chalberg Jr. |
Clinical Trial Stage Projects |
A Phase 1b, Randomized, Blinded, Placebo-Controlled Dose-Ranging Study of GNSC-001 Evaluating Safety, Pharmacodynamics, and Biomarkers in Knee OA |
$11,637,194 |
| Tachyon Therapeutics, Inc |
Ivan King |
Clinical Trial Stage Projects |
TACH101: A Potent, First-In-Class KDM4 Inhibitor for Advanced Cancers |
$3,525,000 |
| City of Hope, Beckman Research Institute |
Ryotaro Nakamura |
Clinical Trial Stage Projects |
Treatment of Severe Aplastic Anemia by induction of mixed chimerism using CD4+ T cell depleted haploidentical donor stem cell transplant |
$9,054,216 |
| Stanford University |
Alice Bertaina |
Clinical Trial Stage Projects |
Sequential same donor αβdepleted-HSCT from an HLA-partially matched donor allowing immunosuppression free kidney transplant |
$11,998,188 |
| Neurona Therapeutics |
Dr. Cory R Nicholas |
Clinical Trial Stage Projects |
Phase 1/2 Study of NRTX-1001 Neural Cell Therapy in Subjects with Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy |
$7,999,999 |
| Excision BioTherapeutics |
Mr. Daniel Dornbusch |
Clinical Trial Stage Projects |
Phase 1 Clinical research program for functional cure of HIV with EBT-101, in-vivo gene therapy |
$4,940,000 |
| Wake Forest University Health Sciences |
James Yoo |
Clinical Trial Stage Projects |
Phase I Treatment of Urethral Strictures in Humans |
$1,250,000 |
| Stanford University |
Dr. Rosa Bacchetta |
Clinical Trial Stage Projects |
Phase 1 Study of Autologous CD4LVFOXP3 in Participants with IPEX Syndrome |
$11,999,179 |
| City of Hope, Beckman Research Institute |
Dr Jana Portnow |
Clinical Trial Stage Projects |
A Phase I Study of Multiple doses of NSC-Based Oncolytic Virotherapy Administered Intracerebrally to Patients with Recurrent High-Grade Gliomas |
$11,999,984 |
| University of California, Davis |
Peter C Belafsky |
Clinical Trial Stage Projects |
A Double-Blind Randomized Placebo-Controlled Investigation of Autologous Muscle Derived Progenitor Cells for the Treatment of Dysphagia |
$11,015,936 |
| BioEclipse Therapeutics INC. |
Dr. Pamela Reilly Contag |
Clinical Trial Stage Projects |
PHASE 1, OPEN LABEL, DOSE-ESCALATION STUDY OF CRX100 IN PATIENTS WITH ADVANCED SOLID TUMORS |
$7,999,689 |
| Stanford University |
Dr. Joseph C. Wu |
Clinical Trial Stage Projects |
A Phase I, Pilot Study of Human Embryonic Stem Cell-Derived Cardiomyocytes in PaTients with ChrOnic Ischemic Left VentRicular Dysfunction (HECTOR) |
$6,987,507 |
| Stanford University |
Crystal Mackall |
Clinical Trial Stage Projects |
Phase 1 Clinical Trial of Autologous GD2 Chimeric Antigen Receptor T Cells for Diffuse Intrinsic Pontine Gliomas and Spinal Diffuse Midline Glioma |
$11,998,310 |
| Stanford University |
Dr. Matthew H Porteus |
Clinical Trial Stage Projects |
Phase 1/1b study of T-allo10 infusion after HLA-partially matched abdepleted-HSCT in children and young adults with hematologic malignancies. |
$10,563,822 |
| Stanford University |
Dr. Gary Steinberg |
Clinical Trial Stage Projects |
Safety and Tolerability Study of Neural Stem Cells (NR1) in Subjects with Chronic Ischemic Subcortical Stroke |
$11,998,988 |
| Cedars-Sinai Medical Center |
Clive Svendsen |
Clinical Trial Stage Projects |
CNS10-NPC-GDNF delivered into the motor cortex for the treatment of ALS |
$11,990,372 |
| City of Hope, Beckman Research Institute |
Dr. Leo D Wang |
Clinical Trial Stage Projects |
Phase I Study of IL13Rα2-Targeting CAR T Cells After Lymphodepletion for Children with Refractory or Recurrent Malignant Brain Tumors |
$8,401,309 |
| Immune-Onc Therapeutics |
Joseph Paul Woodard |
Clinical Trial Stage Projects |
Phase 1 Clinical Development of IO-202, A First-in-Class Antibody Targeting LILRB4, for the Treatment of AML with Monocytic Differentiation and CMML |
$6,000,000 |
| University of California, Davis |
Dr. Diana L. Farmer |
Clinical Trial Stage Projects |
The CuRe Trial: Cellular Therapy for In Utero Myelomeningocele Repair |
$8,905,054 |
| Rocket Pharmaceuticals, Inc. |
Dr. Gayatri Rao |
Clinical Trial Stage Projects |
A Phase I Clinical Trial for a Lentiviral Gene Therapy Targeting the TCIRG1 Gene for Infantile Malignant Osteopetrosis (IMO) |
$1,010,000 |
| University of California, San Francisco |
Steven G. Deeks |
Clinical Trial Stage Projects |
Anti-HIV duoCAR-T cell therapy for HIV infection |
$8,970,732 |
