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Institution
Researcher name
Grant Type
Grant Title
Award Value
Scripps Research Institute
Stuart A Lipton
Quest – Discovery Stage Research Projects
Drug Development of Inhibitors of Inflammation Using Human iPSC-Derived Microglia (hiMG)
$1,658,123
University of California, Los Angeles
Dr Dinesh S Rao
Quest – Discovery Stage Research Projects
Novel methods to eliminate cancer stem cells
$1,384,347
University of California, San Diego
Dr. Michael Karin
Quest – Discovery Stage Research Projects
Targeting pancreatic cancer stem cells with DDR1 antibodies.
$1,425,600
Cedars-Sinai Medical Center
Dr. Robert Barrett
Quest – Discovery Stage Research Projects
A new precision medicine based iPSC-derived model to study personalized intestinal fibrosis treatments in pediatric patients with Crohn’s disease
$776,340
Scripps Research Institute
Dr Michael J Bollong
Quest – Discovery Stage Research Projects
Therapeutics to overcome the differentiation roadblock in Myelodysplastic Syndrome (MDS)
$1,244,160
University of California, Davis
Dr. Kyle D Fink PhD
Quest – Discovery Stage Research Projects
AAV-dCas9 Epigenetic Editing for CDKL5 Deficiency Disorder
$1,429,378
University of California, Los Angeles
Dr. Caroline Y. Kuo
Quest – Discovery Stage Research Projects
Defining the Optimal Gene Therapy Approach of Human Hematopoietic Stem Cells for the Treatment of Dedicator of Cytokinesis 8 (DOCK8) Deficiency
$1,386,232
University of California, Los Angeles
Dr. Donald B. Kohn PhD
Quest – Discovery Stage Research Projects
Hematopoietic Stem Cell Gene Therapy for Alpha Thalassemia
$1,177,739
Stanford University
Dr. Judith A Shizuru
Quest – Discovery Stage Research Projects
Targeted Immunotherapy-Based Blood Stem Cell Transplantation
$1,341,910
Tenaya Therapeutics, Inc.
Karl N Doerner
Quest – Discovery Stage Research Projects
Cardiac Reprogramming Gene Therapy for Post-Myocardial Infarction Heart Failure
$1,017,000
Intact Therapeutics, Inc.
Jeffrey Linhardt
Quest – Discovery Stage Research Projects
Modulation of oral epithelium stem cells by RSpo1 for the prevention and treatment of oral mucositis
$942,050
Cytonus Therapeutics, Inc.
Dr. Edward Filardo
Quest – Discovery Stage Research Projects
Development of a novel stem-cell based carrier for intravenous delivery of oncolytic viruses
$899,342
Salk Institute for Biological Studies
Ronald Mark Evans
Quest – Discovery Stage Research Projects
Extending Immune-Evasive Human Islet-Like Organoids (HILOs) Survival and Function as a Cure for T1D
$1,523,285
Stanford University
Ansuman Satpathy
Quest – Discovery Stage Research Projects
Preclinical development of an exhaustion-resistant CAR-T stem cell for cancer immunotherapy
$1,420,200
Stanford University
Dr. Bertha Chen
Quest – Discovery Stage Research Projects
iPSC-derived smooth muscle cell progenitor conditioned medium for treatment of pelvic organ prolapse
$1,420,200
University of California, San Francisco
Brian Feeley
Quest – Discovery Stage Research Projects
Matrix Assisted Cell Transplantation of Promyogenic Fibroadipogenic Progenitor (FAP) Stem Cells
$1,179,478
University of California, Los Angeles
Prof. Song Li
Quest – Discovery Stage Research Projects
iPSC Extracellular Vesicles for Diabetes Therapy
$1,354,928
Scripps Health
Dr. Darryl D. D’Lima
Quest – Discovery Stage Research Projects
Meniscal Repair and Regeneration
$1,361,775
The Stone Research Foundation for Sports Medicine and Arthritis
Dr. Kevin Stone
Quest – Discovery Stage Research Projects
A Novel Therapy for Articular Cartilage Autologous Cellular Repair by Paste Grafting
$1,180,309
University of California, San Diego
Gene Wei-Ming Yeo
Quest – Discovery Stage Research Projects
RNA-directed therapy for Huntington’s disease
$1,253,110
University of California, Irvine
Dr. Mathew Mark Blurton-Jones
Quest – Discovery Stage Research Projects
Transplantation of genetically corrected iPSC-microglia for the treatment of Sanfilippo Syndrome (MPSIIIA)
$1,083,379
University of California, San Francisco
Dr. Julie Deane Saba
Quest – Discovery Stage Research Projects
Providing a cure for sphingosine phosphate lyase insufficiency syndrome (SPLIS) through adeno-associated viral mediated SGPL1 gene therapy
$1,463,400
Scripps Research Institute
Luke L Lairson
Quest – Discovery Stage Research Projects
Improving the efficacy and tolerability of clinically validated remyelination-inducing molecules using developable combinations of approved drugs
$1,554,126
University of California, San Francisco
Dr Julia Carnevale
Quest – Discovery Stage Research Projects
Generating deeper and more durable BCMA CAR T cell responses in Multiple Myeloma through non-viral knockin/knockout multiplexed genome engineering
$1,463,368
Stanford University
Dr. Sarah C Heilshorn
Quest – Discovery Stage Research Projects
Injectable, autologous iPSC-based therapy for spinal cord injury
$789,000
Navega Therapeutics
Ana Maria Moreno
Quest – Discovery Stage Research Projects
Optimization of a gene therapy for inherited erythromelalgia in iPSC-derived neurons
$1,157,313
Cedars-Sinai Medical Center
Dr Eduardo Marban
Quest – Discovery Stage Research Projects
New noncoding RNA chemical entity for heart failure with preserved ejection fraction.
$1,397,412
Stanford University
Dr. Stanley Qi
Quest – Discovery Stage Research Projects
A novel hybrid CRISPR tool for gene network perturbation and hiPSC engineering
$704,661
University of California, San Diego
Ziwei Huang
Quest – Discovery Stage Research Projects
Development of a new therapeutic for directing target specific stem cell migration and treatment
$1,129,512
University of California, San Diego
Dan S Kaufman
Quest – Discovery Stage Research Projects
Human iPSC-derived chimeric antigen receptor expressing macrophages for improved cancer treatment.
$1,256,332
Stanford University
Dr. Marius Wernig MD, PhD
Quest – Discovery Stage Research Projects
A universally applicable skin sheet for Dystrophic Epidermolysis Bullosa via next-generation gene editing, iPS cell technology and tissue engineering
$1,229,040
University of California, Davis
Dr. David J Segal PhD
Quest – Discovery Stage Research Projects
AAV9-Cas13 gene therapy for Angelman syndrome
$1,364,903
Stanford University
Dr. Phillip C Yang
Quest – Discovery Stage Research Projects
Hypoxia-specific Production of Exosomes from iPSC-derivatives for Myocardial Repair
$1,418,023
Stanford University
Kathleen M Sakamoto
Quest – Discovery Stage Research Projects
Small Molecules to inhibit Nemo-like Kinase for Treatment of Diamond Blackfan Anemia
$847,923
University of California, Irvine
Munjal M Acharya
Quest – Discovery Stage Research Projects
Stem cell-derived extracellular vesicles to reverse radiation-induced brain injury
$1,064,724
University of California, San Francisco
Dr Marisa Medina
Quest – Discovery Stage Research Projects
iPSCs as a screening tool to predict risk of nonalcoholic fatty liver disease
$813,000
University of California, San Diego
Dr. Tannishtha Reya
Quest – Discovery Stage Research Projects
Targeting Critical Regulators of Cancer Stem Cells
$1,148,264
University of California, Davis
Dr. Deborah K Lieu
Quest – Discovery Stage Research Projects
Building a hiPSC-based biopacemaker
$1,260,827
City of Hope, Beckman Research Institute
Professor Yanhong Shi
Quest – Discovery Stage Research Projects
Combating COVID-19 using human PSC-derived NK cells
$249,998
University of California, San Diego
Tariq M Rana
Quest – Discovery Stage Research Projects
Development of COVID-19 Antiviral Therapy Using Human iPSC-Derived Lung Organoids
$250,000
University of California, Los Angeles
Dr. Thomas Carmichael M.D., Ph.D.
Quest – Discovery Stage Research Projects
Human-induced pluripotent stem cell-derived glial enriched progenitors to treat white matter stroke and vascular dementia.
$250,000
University of California, Irvine
Robert F. Hunt
Quest – Discovery Stage Research Projects
Optimization of a human interneuron cell therapy for traumatic brain injury
$240,000
University of Southern California
Dr. Justin K Ichida
Quest – Discovery Stage Research Projects
Development of a SYF2 antisense oligonucleotide (ASO) treatment for ALS
$222,300
University of California, Irvine
Dr. Mathew Mark Blurton-Jones
Quest – Discovery Stage Research Projects
Transplantation of Pluripotent Stem Cell Derived Microglia for the Treatment of Adult-onset Leukoencephalopathy (HDLS/ALSP)
$214,668
Vitabolus, Inc.
Aline Betancourt
Quest – Discovery Stage Research Projects
The First Orally Delivered Cell Therapy for the Treatment of Inflammatory Bowel Disease
$249,000
Lundquist Institute for Biomedical Innovation at Harbor – UCLA Medical Center
Dr Eiji Yoshihara PhD
Quest – Discovery Stage Research Projects
Dual angiogenic and immunomodulating nanotechnology for subcutaneous stem cell derived islet transplantation for the treatment of diabetes
$250,000
University of California, Los Angeles
Dr. Donald B. Kohn PhD
Quest – Discovery Stage Research Projects
Hematopoietic Stem Cell Gene Therapy for X-linked Agammaglobulinemia
$219,230
University of California, San Diego
Dan S Kaufman
Quest – Discovery Stage Research Projects
Human iPSC-derived chimeric antigen receptor-expressing macrophages for cancer treatment
$222,200
Stanford University
Alan G Cheng
Quest – Discovery Stage Research Projects
Modulation of the Wnt pathway to restore inner ear function
$1,389,416
University of California, San Diego
Prof James S Hagood
Quest – Discovery Stage Research Projects
Mesenchymal stem cell extracellular vesicles as therapy for pulmonary fibrosis
$0
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