All CIRM Grants

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Institution Researcher name Grant Type Grant Title Award Value
University of California, Los Angeles Dr. Scott G Kitchen Therapeutic Translational Research Projects Hematopoietic Stem/Progenitor Cell-Based Chimeric Antigen Receptor Gene Therapy for HIV Infection $6,140,723
Rejuvenation Technologies, Inc. John Ramunas Therapeutic Translational Research Projects Telomerase mRNA for short telomere related pulmonary fibrosis $3,984,942
University of Southern California Dr. Rongfu Wang Therapeutic Translational Research Projects Novel T cell receptor-STEM T cell immunotherapy in lung cancer $5,689,540
Stanford University Walter Park Therapeutic Translational Research Projects Enhanced Autologous Pancreatic Islet Transplantation and Survival for Diabetes Mellitus Therapy $6,054,165
VxBiosciences inc. Dr. Christina Chuong Therapeutic Translational Research Projects Escape-Resistant Oligonucleotide Therapy (ONT) for Cytomegalovirus (CMV) Disease in Hematopoietic Stem-Cell and Solid-Organ Transplant Patients $3,977,180
City of Hope, Beckman Research Institute Dr Jianhua Yu Therapeutic Translational Research Projects Specific Targeting Hypoxia Metastatic Breast Tumor with Allogeneic Off-the-Shelf Anti-EGFR CAR NK Cells Expressing an ODD domain of HIF-1α $6,036,002
Mahzi Therapeutics Dr. Allyson Berent Therapeutic Translational Research Projects Development of a Gene Therapy for the Treatment of Pitt Hopkins Syndrome (PHS) – Translating from Animal Proof of Concept to Support Pre-IND Meeting $3,800,760
University of California, Davis Dr. William J Murphy Therapeutic Translational Research Projects Overcoming resistance to standard CD19-targeted CAR T using a novel triple antigen targeted vector $3,869,061
University of California, San Diego Stephanie Cherqui Therapeutic Translational Research Projects CRISPR/Cas9-mediated gene editing of Hematopoietic stem and progenitor cells for Friedreich’s ataxia $4,846,579
University of Southern California Preet M Chaudhary Therapeutic Translational Research Projects Next generation affinity-tuned CAR for prostate cancer $5,805,144
University of California, Los Angeles Dr. Donald B. Kohn PhD Therapeutic Translational Research Projects Autologous MPO Knock-Out Hematopoietic Stem and Progenitor Cells for Pulmonary Arterial Hypertension $4,751,297
Ray Therapeutics, INC Paul Bresge Therapeutic Translational Research Projects Optogenetic therapy for treating retinitis pigmentosa and other inherited retinal diseases $3,999,553
University of California, Irvine Dr. Aileen J Anderson Therapeutic Translational Research Projects A human neural stem cell therapeutic candidate for the treatment of chronic cervical spinal cord injury $4,950,024
University of California, San Francisco Arun P Wiita Therapeutic Translational Research Projects CD72 nanoCARs for the treatment of refractory pediatric B-cell acute lymphoblastic leukemia $3,330,801
MyoGene Bio LLC Dr Courtney Young Therapeutic Translational Research Projects Development of MyoDys45-55, a gene editing therapy for Duchenne muscular dystrophy $3,400,000
Immusoft Corporation Dr Robert Hayes Therapeutic Translational Research Projects MPS II: Plasma cell delivery of iduronate sulfatase $3,994,676
Regencor, Inc. PILAR RUIZ-LOZANO Therapeutic Translational Research Projects IND-enabling Studies of Wearable Evolve-FSTL1 for Cardiac Regeneration after MI $3,923,191
University of California, San Francisco Dr. Hideho Okada Therapeutic Translational Research Projects Development of novel synNotch CART cell therapy in patients with recurrent EGFRvIII+ glioblastoma $4,556,536
ImmunoVec Luke Riggan Therapeutic Translational Research Projects Hematopoietic Stem Cell Gene Therapy for IPEX Syndrome $3,551,332
University of California, Los Angeles Dr. Arjun Deb Therapeutic Translational Research Projects Targeting stromal progenitors to prevent the development of heart failure $4,714,824
Palo Alto Veterans Institute for Research Irene Lorenzo Llorente Therapeutic Translational Research Projects Clinical Translation of Allogenic Regenerative Cell Therapy for White Matter Stroke and Vascular Dementia $5,149,913
University of California, Los Angeles Dr. Irene L. Llorente Therapeutic Translational Research Projects Clinical Translation of Allogenic Regenerative Cell Therapy for White Matter Stroke and Vascular Dementia $707,754
Juvena Therapeutics Inc. Jeremy D O’Connell Therapeutic Translational Research Projects Clinical Translation of hESC-derived protein therapy that positively regulates the regenerative capacity of post-natal muscle for treating DM1  $3,906,376
University of California, Los Angeles Cristina Puig Saus Therapeutic Translational Research Projects CAR-Tnm cell therapy for melanoma targeting TYRP-1 $5,904,462
University of California, Los Angeles Dr. Lili Yang Therapeutic Translational Research Projects HSC-Engineered Off-The-Shelf CAR-iNKT Cell Therapy for Multiple Myeloma $5,281,199
University of California, San Francisco Dr. Hideho Okada Therapeutic Translational Research Projects Development of novel synNotch CART cell therapy in patients with recurrent EGFRvIII+ glioblastoma $525,000
Sanford Burnham Prebys Medical Discovery Institute Dr. Evan Y. Snyder Therapeutic Translational Research Projects Human Neural Stem Cells (hNSCs) for neuroprotection in perinatal hypoxic-ischemic brain injury (HII)-Pre-IND-enabling Studies $4,963,684
Neurona Therapeutics Dr. Cory R Nicholas Therapeutic Translational Research Projects Development of a human stem cell-derived inhibitory neuron therapeutic for the treatment of chronic focal epilepsy $4,848,505
University of California, San Diego Mark H Tuszynski Therapeutic Translational Research Projects Human Embryonic Stem Cell-Derived Neural Stem Cells for Severe Spinal Cord Injury (SCI) $6,235,897
University of California, Los Angeles Yvonne Y. Chen Therapeutic Translational Research Projects BCMA/CS1 Bispecific CAR-T Cell Therapy to Prevent Antigen Escape in Multiple Myeloma $3,176,805
University of California, Irvine Dr. Brian J. Cummings Therapeutic Translational Research Projects An optimized human neural stem cell line (hNSC) for the treatment of traumatic brain injury (TBI) $4,804,737
City of Hope, Beckman Research Institute Prof. Karen S Aboody M.D. Therapeutic Translational Research Projects Neural Stem cell-mediated oncolytic immunotherapy for ovarian cancer $2,873,262
University of California, Los Angeles Dr. Caroline Y. Kuo Therapeutic Translational Research Projects Ex Vivo Gene Editing of Human Hematopoietic Stem Cells for the Treatment of X-Linked Hyper-IgM Syndrome $4,896,628
University of Southern California Dr. Mark S Humayun Therapeutic Translational Research Projects PRPE-SF, polarized hESC-derived RPE Soluble Factors, as a Therapy for Early Stage Dry Age-related Macular Degeneration $3,697,935
Stanford University Dr. Theodore Leng Therapeutic Translational Research Projects NeuBright, a purified allogeneic cell therapy product for treatment of Dry Age-related Macular Degeneration $4,235,758
University of California, Los Angeles Steven Schwartz Therapeutic Translational Research Projects Clinical Translation of Autologous Regenerative Cell Therapy for Blindness $5,068,026
University of California, San Francisco Dr. Karin Lindgren Gaensler Therapeutic Translational Research Projects Developing engineered autologous leukemia vaccines to target residual leukemic stem cells $4,171,728
University of California, Irvine Dr. Magdalene J Seiler Therapeutic Translational Research Projects Morphological and functional integration of stem cell derived retina organoid sheets into degenerating retina models $4,769,039
Stanford University Dr. Bertha Chen Therapeutic Translational Research Projects Autologous iPSC-derived smooth muscle cell therapy for treatment of urinary incontinence $5,977,155
MAX BioPharma, Inc. Dr. Farhad Parhami Phd, MBA Therapeutic Translational Research Projects Therapeutic development of Oxy200, an oxysterol with bone anabolic and anti-resorptive properties for intervention in osteoporosis $1,400,000
University of California, San Diego Dan S Kaufman Therapeutic Translational Research Projects Human Embryonic Stem Cell-Derived Natural Killer Cells for Cancer Treatment $3,260,000
University of California, San Diego Catriona Jamieson Therapeutic Translational Research Projects A Splicing Modulator Targeting Cancer Stem Cells in Acute Myeloid Leukemia $2,511,767
Stanford University Dr. Anthony E. Oro Therapeutic Translational Research Projects DEBCT: Genetically Corrected, Induced Pluripotent Cell-Derived Epithelial Sheets for Definitive Treatment of Dystrophic Epidermolysis Bullosa $5,107,353
University of California, San Diego Ezra Cohen Therapeutic Translational Research Projects Development of ROR1 CAR-T cells to target cancer stem cells in advanced malignancies $5,795,584
University of California, San Diego Dr Karen Christman Therapeutic Translational Research Projects Injectable pro-regenerative scaffold for treating symptomatic peripheral artery disease $2,839,317
Gladstone Institutes, J. David Dr. Yadong Huang Therapeutic Translational Research Projects Human iPSC-derived GABAergic Progenitors for Alzheimer’s Disease Treatment $1,900,000
University of California, San Francisco Mark C. Walters M.D. Therapeutic Translational Research Projects Curing Sickle cell Disease with CRISPR-Cas9 genome editing $60,635
UCSF Benioff Children’s Hospital Oakland Dr. Mark C. Walters M.D. Therapeutic Translational Research Projects Curing Sickle cell Disease with CRISPR-Cas9 genome editing $4,394,276
University of Southern California Dr. Denis A Evseenko Dr. Therapeutic Translational Research Projects Pluripotent stem cell-derived chondrocytes for articular cartilage repair $2,503,104
Ankasa Regenerative Therapeutics, Inc. Ying Zhu Therapeutic Translational Research Projects An autologous somatic stem cell therapy for the treatment of osteonecrosis $2,088,780
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