Our Grants

CIRM provides funding across five key areas: Infrastructure, Education, Discovery Research, Translational Research, and Clinical Research. By supporting projects at every stage of development, from initial discovery to clinical trials, CIRM drives progress in regenerative medicine and accelerates innovative therapies to patients.

Check out our portfolio of awards below. Click here to see a list of People We’ve Funded.

All CIRM Grants

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Institution Researcher name Grant Type Grant Title Award Value
Neurona Therapeutics Dr. Cory R Nicholas Therapeutic Translational Research Projects Development of a universal allogeneic human interneuron cell therapy candidate for the treatment of drug resistant focal epilepsy. $3,828,714
City of Hope, Beckman Research Institute Lei Tian Therapeutic Translational Research Projects Targeting pancreatic cancer with Allogeneic Off-the-Shelf PSCA-CAR NK cells $0
University of California, Los Angeles Dr. Lili Yang Therapeutic Translational Research Projects Combating Ovarian Cancer with Stem Cell-Engineered Off-The-Shelf CAR-NKT Cell Therapy $5,601,600
Stanford University Natalia Gomez-Ospina Therapeutic Translational Research Projects Toward a Cure for Gaucher Disease Type 1: Autologous Transplantation of Genome Edited Hematopoietic Stem Cells $4,696,296
Replay Holdings, Inc Anthony Conway Therapeutic Translational Research Projects Hypoimmunogenic iPSC-derived TCR-NK cells for oncology $0
AcuraStem Incorporated Mr. Samuel V. Alworth MS, MBA Therapeutic Translational Research Projects Development of AS-241, an UNC13A Targeting Antisense Oligonucleotide (ASO) Treatment for ALS, for IND-enabling Studies $4,012,325
Axent Biosciences Inc. Abhay Joshi Therapeutic Translational Research Projects A high quality, accessible cell therapy for Parkinson’s Disease produced in a scalable bioreactor system for 3D cell expansion and differentiation $3,999,241
University of California, Los Angeles Dr. Gerald Lipshutz DDS, MD, MS Therapeutic Translational Research Projects Development of a Gene Therapy for Treatment of Guanidinoacetate Methyltransferase Deficiency-Translating In Vivo Proof of Concept to Support a Pre-IND $5,145,825
Ray Therapeutics, INC Paul Bresge Therapeutic Translational Research Projects Optogenetic Therapy for Treatment of Geographic Atrophy $3,998,930
University of California, San Francisco Sarah Monica Knox Therapeutic Translational Research Projects Neurogenic hydrogel stimulation of stem cells to regenerate radiation-damaged salivary glands $2,312,021
Siren Biotechnology, Inc. Dr Nicole K Paulk Therapeutic Translational Research Projects Development of an AAV gene therapy immunotherapy for the treatment of glioblastoma $3,997,919
Cedars-Sinai Medical Center Dr. Ahmed Gamal Ibrahim Therapeutic Translational Research Projects Noncoding RNA drug TY1 as a therapeutic candidate for scleroderma and systemic sclerosis $2,590,224
University of California, San Diego Dr Karen Christman Therapeutic Translational Research Projects Pro-regenerative infusible ECM biomaterial for treating acute myocardial infarction $4,353,438
University of California, Los Angeles Zulema Romero Garcia Therapeutic Translational Research Projects Adenine Base Editing for Autologous Hematopoietic Stem Cell Gene Therapy of CD3δ SCID $5,966,928
University of California, Los Angeles Dr. Donald B. Kohn PhD Therapeutic Translational Research Projects Hematopoietic Stem Cell Gene Editing for X-linked Agammaglobulinemia (XLA) $4,304,883
University of California, San Diego Dr. Eric D. Adler MD Therapeutic Translational Research Projects Ex Vivo Modified Hematopoietic Stem Cells to Treat Danon Disease $5,180,389
University of California, Los Angeles Dr. Gerald Lipshutz DDS, MD, MS Therapeutic Translational Research Projects Development of a Gene Therapy for the Treatment of Arginase Deficiency – Translating from Proof of Concept to Support Pre-IND Meeting $5,266,504
City of Hope, Beckman Research Institute Dr Michael A. Caligiuri Therapeutic Translational Research Projects Targeting multiple myeloma with BCMA-CAR NK cells expressing a GPRC5D-NKG2D bispecific antibody $6,036,001
University of California, Los Angeles Anthony J Aldave Therapeutic Translational Research Projects AAV Gene Therapy for Treating Congenital Hereditary Endothelial Dystrophy associated with Biallelic SLC4A11 Mutations $4,338,166
ImmunoVec Luke Riggan Therapeutic Translational Research Projects Hematopoietic Stem Cell Gene Therapy for Wiskott Aldrich Syndrome $3,999,899
BrainXell Therapeutics Maria Daniela Cirnaru Therapeutic Translational Research Projects Development of Autologous Cell Replacement Therapy for Parkinson’s Disease: Path to Personalized Treatment $3,841,110
University of California, Los Angeles Dr. Sophie X Deng Therapeutic Translational Research Projects Extracellular Vesicle-Based Therapy for Corneal Scars $5,779,276
University of California, Los Angeles Dr. Scott G Kitchen Therapeutic Translational Research Projects Hematopoietic Stem/Progenitor Cell-Based Chimeric Antigen Receptor Gene Therapy for HIV Infection $6,140,723
Rejuvenation Technologies, Inc. John Ramunas Therapeutic Translational Research Projects Telomerase mRNA for short telomere related pulmonary fibrosis $3,984,942
University of Southern California Dr. Rongfu Wang Therapeutic Translational Research Projects Novel T cell receptor-STEM T cell immunotherapy in lung cancer $5,689,540
Stanford University Walter Park Therapeutic Translational Research Projects Enhanced Autologous Pancreatic Islet Transplantation and Survival for Diabetes Mellitus Therapy $6,054,165
University of California, Irvine Jianhua Yu Therapeutic Translational Research Projects Specific Targeting Hypoxia Metastatic Breast Tumor with Allogeneic Off-the-Shelf Anti-EGFR CAR NK Cells Expressing an ODD domain of HIF-1α $4,769,410
VxBiosciences inc. Dr. Christina Chuong Therapeutic Translational Research Projects Escape-Resistant Oligonucleotide Therapy (ONT) for Cytomegalovirus (CMV) Disease in Hematopoietic Stem-Cell and Solid-Organ Transplant Patients $730,000
City of Hope, Beckman Research Institute Lei Tian Therapeutic Translational Research Projects Specific Targeting Hypoxia Metastatic Breast Tumor with Allogeneic Off-the-Shelf Anti-EGFR CAR NK Cells Expressing an ODD domain of HIF-1α $1,266,592
Mahzi Therapeutics Dr. Allyson Berent Therapeutic Translational Research Projects Development of a Gene Therapy for the Treatment of Pitt Hopkins Syndrome (PHS) – Translating from Animal Proof of Concept to Support Pre-IND Meeting $3,800,760
University of California, Davis Dr. William J Murphy Therapeutic Translational Research Projects Overcoming resistance to standard CD19-targeted CAR T using a novel triple antigen targeted vector $3,869,061
University of California, San Diego Stephanie Cherqui Therapeutic Translational Research Projects CRISPR/Cas9-mediated gene editing of Hematopoietic stem and progenitor cells for Friedreich’s ataxia $4,846,579
University of Southern California Preet M Chaudhary Therapeutic Translational Research Projects Next generation affinity-tuned CAR for prostate cancer $5,805,144
University of California, Los Angeles Dr. Donald B. Kohn PhD Therapeutic Translational Research Projects Autologous MPO Knock-Out Hematopoietic Stem and Progenitor Cells for Pulmonary Arterial Hypertension $4,751,297
Ray Therapeutics, INC Paul Bresge Therapeutic Translational Research Projects Optogenetic therapy for treating retinitis pigmentosa and other inherited retinal diseases $3,999,553
University of California, Irvine Dr. Aileen J Anderson Therapeutic Translational Research Projects A human neural stem cell therapeutic candidate for the treatment of chronic cervical spinal cord injury $4,950,024
University of California, San Francisco Arun P Wiita Therapeutic Translational Research Projects CD72 nanoCARs for the treatment of refractory pediatric B-cell acute lymphoblastic leukemia $3,330,801
MyoGene Bio LLC Dr Courtney Young Therapeutic Translational Research Projects Development of MyoDys45-55, a gene editing therapy for Duchenne muscular dystrophy $3,400,000
Immusoft Corporation Dr Robert Hayes Therapeutic Translational Research Projects MPS II: Plasma cell delivery of iduronate sulfatase $3,994,676
Regencor, Inc. PILAR RUIZ-LOZANO Therapeutic Translational Research Projects IND-enabling Studies of Wearable Evolve-FSTL1 for Cardiac Regeneration after MI $3,923,191
University of California, San Francisco Dr. Hideho Okada Therapeutic Translational Research Projects Development of novel synNotch CART cell therapy in patients with recurrent EGFRvIII+ glioblastoma $4,556,536
ImmunoVec Luke Riggan Therapeutic Translational Research Projects Hematopoietic Stem Cell Gene Therapy for IPEX Syndrome $3,551,332
University of California, Los Angeles Dr. Arjun Deb Therapeutic Translational Research Projects Targeting stromal progenitors to prevent the development of heart failure $4,714,824
Palo Alto Veterans Institute for Research Irene Lorenzo Llorente Therapeutic Translational Research Projects Clinical Translation of Allogenic Regenerative Cell Therapy for White Matter Stroke and Vascular Dementia $5,149,913
University of California, Los Angeles Dr. Irene L. Llorente Therapeutic Translational Research Projects Clinical Translation of Allogenic Regenerative Cell Therapy for White Matter Stroke and Vascular Dementia $707,754
Juvena Therapeutics Inc. Jeremy D O’Connell Therapeutic Translational Research Projects Clinical Translation of hESC-derived protein therapy that positively regulates the regenerative capacity of post-natal muscle for treating DM1  $3,906,376
University of California, Los Angeles Cristina Puig Saus Therapeutic Translational Research Projects CAR-Tnm cell therapy for melanoma targeting TYRP-1 $5,904,462
University of California, Los Angeles Dr. Lili Yang Therapeutic Translational Research Projects HSC-Engineered Off-The-Shelf CAR-iNKT Cell Therapy for Multiple Myeloma $5,281,199
University of California, San Francisco Dr. Hideho Okada Therapeutic Translational Research Projects Development of novel synNotch CART cell therapy in patients with recurrent EGFRvIII+ glioblastoma $525,000
Sanford Burnham Prebys Medical Discovery Institute Dr. Evan Y. Snyder Therapeutic Translational Research Projects Human Neural Stem Cells (hNSCs) for neuroprotection in perinatal hypoxic-ischemic brain injury (HII)-Pre-IND-enabling Studies $4,963,684
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