All CIRM Grants

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Institution Researcher name Grant Type Grant Title Award Value
University of California, Los Angeles Dr. Richard Joseph Pietras Quest – Discovery Stage Research Projects Reversal of dysregulated myelopoiesis in breast cancers and cancer stem cells to boost antitumor immunotherapy $2,327,680
Greenstone Biosciences, Inc. Paul D Pang Quest – Discovery Stage Research Projects Drug Discovery for Duchenne Muscular Dystrophy Using Patient-Derived Human iPSCs $675,000
University of California, Berkeley Mr. Fyodor Urnov Quest – Discovery Stage Research Projects A Treatment for Artemis-deficient Severe Combined Immunodeficiency using Non-Viral CRISPR-driven Safe Harbor Transgenesis in Hematopoietic Stem Cells $1,809,372
University of California, Davis Aijun Wang PhD Quest – Discovery Stage Research Projects In Utero Treatment of Duchenne Muscular Dystrophy with Non-viral Gene Editing $2,035,544
Rubedo Life Sciences Inc. Marco Quarta Quest – Discovery Stage Research Projects Pharmacological regenerative treatment of idiopathic pulmonary fibrosis targeting the senescent niche of lung progenitor cells. $1,450,876
University of California, Los Angeles Dr. Gerald Lipshutz Quest – Discovery Stage Research Projects Gene Therapy for SLC6A8 Creatine Transporter Disorder $2,296,920
University of California, Los Angeles Frank Pajonk Quest – Discovery Stage Research Projects Development of novel small molecules against cancer stem cells in solid cancers $2,340,000
Scripps Health Dr. Darryl D. D’Lima Quest – Discovery Stage Research Projects Pluripotent Stem Cells for Tendon Tissue Engineering $2,734,163
Cedars-Sinai Medical Center Dmitriy Sheyn Quest – Discovery Stage Research Projects Microgel encapsulated iPSC-derived notochordal cells to treat intervertebral disc degeneration and low back pain $2,020,166
Lundquist Institute for Biomedical Innovation at Harbor – UCLA Medical Center Dr. Michelina Iacovino PhD Quest – Discovery Stage Research Projects A Novel Therapy for Sanfilippo B $2,297,884
University of California, Berkeley 5106433559 Kevin E. Healy Quest – Discovery Stage Research Projects Novel Lipid Nanoparticles for Enhancing eNOS Synthesis for Cardioprotection Post Myocardial Infarction $2,060,248
BrainXell Therapeutics Matthew Goodus Quest – Discovery Stage Research Projects Autologous stem cell-derived interneuron cell therapy for spinal cord injury (SCI) $2,025,000
University of California, San Diego Professor Alysson R Muotri Quest – Discovery Stage Research Projects A treatment for Rett syndrome using glial-restricted neural progenitor cells $1,402,240
Gladstone Institutes, J. David Dr. Deepak Srivastava Quest – Discovery Stage Research Projects Modified RNA-Based Gene Therapy for Cardiac Regeneration Through Cardiomyocyte Proliferation $1,565,784
The Scintillon Institute Brian Lawson Quest – Discovery Stage Research Projects An hematopoietic stem-cell-based approach to treat HIV employing CAR T cells and anti-HIV broadly neutralizing antibodies. $1,143,600
University of California, Irvine Dr. Michael Demetriou Quest – Discovery Stage Research Projects CAR T cells targeting abnormal N-glycans for the treatment of refractory/metastatic solid cancers $1,414,800
University of California, Los Angeles Dr. Lili Yang Quest – Discovery Stage Research Projects Combating Ovarian Cancer Using Stem Cell-Engineered Off-The-Shelf CAR-iNKT Cells $1,404,000
Minutia, Inc. Katy Digovich Quest – Discovery Stage Research Projects Bioengineering human stem cell-derived beta cell organoids to monitor cell health in real time and improve therapeutic outcomes in patients $1,198,550
Nanotools Bioscience Dr. Alex Savtchenko PhD Quest – Discovery Stage Research Projects Enabling non-genetic activity-driven maturation of iPSC-derived neurons $675,000
University of California, Los Angeles Dr. Xian-Jie Yang Quest – Discovery Stage Research Projects Developing gene therapy for dominant optic atrophy using human pluripotent stem cell-derived retinal organoid disease models $1,345,691
University of California, San Diego Dr. Joseph G. Gleeson Quest – Discovery Stage Research Projects Novel antisense therapy to treat genetic forms of neurodevelopmental disease. $1,180,654
Scripps Research Institute Stuart A Lipton Quest – Discovery Stage Research Projects Drug Development of Inhibitors of Inflammation Using Human iPSC-Derived Microglia (hiMG) $1,658,123
University of California, Los Angeles Dr Dinesh S Rao Quest – Discovery Stage Research Projects Novel methods to eliminate cancer stem cells $1,384,347
University of California, San Diego Dr. Michael Karin Quest – Discovery Stage Research Projects Targeting pancreatic cancer stem cells with DDR1 antibodies. $1,425,600
Cedars-Sinai Medical Center Dr. Robert Barrett Quest – Discovery Stage Research Projects A new precision medicine based iPSC-derived model to study personalized intestinal fibrosis treatments in pediatric patients with Crohn’s disease $776,340
Scripps Research Institute Dr Michael J Bollong Quest – Discovery Stage Research Projects Therapeutics to overcome the differentiation roadblock in Myelodysplastic Syndrome (MDS) $1,244,160
University of California, Davis Dr. Kyle D Fink PhD Quest – Discovery Stage Research Projects AAV-dCas9 Epigenetic Editing for CDKL5 Deficiency Disorder $1,429,378
University of California, Los Angeles Dr. Caroline Y. Kuo Quest – Discovery Stage Research Projects Defining the Optimal Gene Therapy Approach of Human Hematopoietic Stem Cells for the Treatment of Dedicator of Cytokinesis 8 (DOCK8) Deficiency $1,386,232
University of California, Los Angeles Dr. Donald B. Kohn PhD Quest – Discovery Stage Research Projects Hematopoietic Stem Cell Gene Therapy for Alpha Thalassemia $1,177,739
Stanford University Dr. Judith A Shizuru Quest – Discovery Stage Research Projects Targeted Immunotherapy-Based Blood Stem Cell Transplantation $1,341,910
Tenaya Therapeutics, Inc. Karl N Doerner Quest – Discovery Stage Research Projects Cardiac Reprogramming Gene Therapy for Post-Myocardial Infarction Heart Failure $1,017,000
Intact Therapeutics, Inc. Jeffrey Linhardt Quest – Discovery Stage Research Projects Modulation of oral epithelium stem cells by RSpo1 for the prevention and treatment of oral mucositis $942,050
Cytonus Therapeutics, Inc. Dr. Edward Filardo Quest – Discovery Stage Research Projects Development of a novel stem-cell based carrier for intravenous delivery of oncolytic viruses $899,342
Salk Institute for Biological Studies Ronald Mark Evans Quest – Discovery Stage Research Projects Extending Immune-Evasive Human Islet-Like Organoids (HILOs) Survival and Function as a Cure for T1D $1,523,285
Stanford University Ansuman Satpathy Quest – Discovery Stage Research Projects Preclinical development of an exhaustion-resistant CAR-T stem cell for cancer immunotherapy $1,420,200
Stanford University Dr. Bertha Chen Quest – Discovery Stage Research Projects iPSC-derived smooth muscle cell progenitor conditioned medium for treatment of pelvic organ prolapse $1,420,200
University of California, San Francisco Brian Feeley Quest – Discovery Stage Research Projects Matrix Assisted Cell Transplantation of Promyogenic Fibroadipogenic Progenitor (FAP) Stem Cells $1,179,478
University of California, Los Angeles Prof. Song Li Quest – Discovery Stage Research Projects iPSC Extracellular Vesicles for Diabetes Therapy $1,354,928
Scripps Health Dr. Darryl D. D’Lima Quest – Discovery Stage Research Projects Meniscal Repair and Regeneration $1,361,775
The Stone Research Foundation for Sports Medicine and Arthritis Dr. Kevin Stone Quest – Discovery Stage Research Projects A Novel Therapy for Articular Cartilage Autologous Cellular Repair by Paste Grafting $1,180,309
University of California, San Diego Gene Wei-Ming Yeo Quest – Discovery Stage Research Projects RNA-directed therapy for Huntington’s disease $1,253,110
University of California, Irvine Dr. Mathew Mark Blurton-Jones Quest – Discovery Stage Research Projects Transplantation of genetically corrected iPSC-microglia for the treatment of Sanfilippo Syndrome (MPSIIIA) $1,083,379
University of California, San Francisco Dr. Julie Deane Saba Quest – Discovery Stage Research Projects Providing a cure for sphingosine phosphate lyase insufficiency syndrome (SPLIS) through adeno-associated viral mediated SGPL1 gene therapy $1,463,400
Scripps Research Institute Luke L Lairson Quest – Discovery Stage Research Projects Improving the efficacy and tolerability of clinically validated remyelination-inducing molecules using developable combinations of approved drugs $1,554,126
University of California, San Francisco Dr Julia Carnevale Quest – Discovery Stage Research Projects Generating deeper and more durable BCMA CAR T cell responses in Multiple Myeloma through non-viral knockin/knockout multiplexed genome engineering $1,463,368
Stanford University Dr. Sarah C Heilshorn Quest – Discovery Stage Research Projects Injectable, autologous iPSC-based therapy for spinal cord injury $789,000
Navega Therapeutics Ana Maria Moreno Quest – Discovery Stage Research Projects Optimization of a gene therapy for inherited erythromelalgia in iPSC-derived neurons $1,157,313
Cedars-Sinai Medical Center Dr Eduardo Marban Quest – Discovery Stage Research Projects New noncoding RNA chemical entity for heart failure with preserved ejection fraction. $1,397,412
Stanford University Dr. Stanley Qi Quest – Discovery Stage Research Projects A novel hybrid CRISPR tool for gene network perturbation and hiPSC engineering $704,661
University of California, San Diego Ziwei Huang Quest – Discovery Stage Research Projects Development of a new therapeutic for directing target specific stem cell migration and treatment $1,129,512
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