Our Grants

CIRM provides funding across five key areas: Infrastructure, Education, Discovery Research, Translational Research, and Clinical Research. By supporting projects at every stage of development, from initial discovery to clinical trials, CIRM drives progress in regenerative medicine and accelerates innovative therapies to patients.

Check out our portfolio of awards below. Click here to see a list of People We’ve Funded.

All CIRM Grants

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Institution Researcher name Grant Type Grant Title Award Value
University of California, Los Angeles Dr. Xian-Jie Yang Quest – Discovery Stage Research Projects Developing gene therapy for dominant optic atrophy using human pluripotent stem cell-derived retinal organoid disease models $1,345,691
University of California, San Diego Dr. Joseph G. Gleeson Quest – Discovery Stage Research Projects Novel antisense therapy to treat genetic forms of neurodevelopmental disease. $1,180,654
Scripps Research Institute Stuart A Lipton Quest – Discovery Stage Research Projects Drug Development of Inhibitors of Inflammation Using Human iPSC-Derived Microglia (hiMG) $1,648,969
University of California, Los Angeles Dr Dinesh S Rao Quest – Discovery Stage Research Projects Novel methods to eliminate cancer stem cells $1,384,345
University of California, San Diego Dr. Michael Karin Quest – Discovery Stage Research Projects Targeting pancreatic cancer stem cells with DDR1 antibodies. $1,425,600
Cedars-Sinai Medical Center Dr. Robert Barrett Quest – Discovery Stage Research Projects A new precision medicine based iPSC-derived model to study personalized intestinal fibrosis treatments in pediatric patients with Crohn’s disease $776,340
Scripps Research Institute Dr Michael J Bollong Quest – Discovery Stage Research Projects Therapeutics to overcome the differentiation roadblock in Myelodysplastic Syndrome (MDS) $1,244,160
University of California, Davis Dr. Kyle D Fink PhD Quest – Discovery Stage Research Projects AAV-dCas9 Epigenetic Editing for CDKL5 Deficiency Disorder $1,429,378
University of California, Los Angeles Dr. Caroline Y. Kuo Quest – Discovery Stage Research Projects Defining the Optimal Gene Therapy Approach of Human Hematopoietic Stem Cells for the Treatment of Dedicator of Cytokinesis 8 (DOCK8) Deficiency $1,386,232
University of California, Los Angeles Dr. Donald B. Kohn PhD Quest – Discovery Stage Research Projects Hematopoietic Stem Cell Gene Therapy for Alpha Thalassemia $1,177,739
Stanford University Dr. Judith A Shizuru Quest – Discovery Stage Research Projects Targeted Immunotherapy-Based Blood Stem Cell Transplantation $1,341,910
Tenaya Therapeutics, Inc. Karl N Doerner Quest – Discovery Stage Research Projects Cardiac Reprogramming Gene Therapy for Post-Myocardial Infarction Heart Failure $1,017,000
Intact Therapeutics, Inc. Jeffrey Linhardt Quest – Discovery Stage Research Projects Modulation of oral epithelium stem cells by RSpo1 for the prevention and treatment of oral mucositis $942,050
Cytonus Therapeutics, Inc. Dr. Edward Filardo Quest – Discovery Stage Research Projects Development of a novel stem-cell based carrier for intravenous delivery of oncolytic viruses $899,342
Salk Institute for Biological Studies Ronald Mark Evans Quest – Discovery Stage Research Projects Extending Immune-Evasive Human Islet-Like Organoids (HILOs) Survival and Function as a Cure for T1D $1,523,285
Stanford University Ansuman Satpathy Quest – Discovery Stage Research Projects Preclinical development of an exhaustion-resistant CAR-T stem cell for cancer immunotherapy $1,420,200
Stanford University Dr. Bertha Chen Quest – Discovery Stage Research Projects iPSC-derived smooth muscle cell progenitor conditioned medium for treatment of pelvic organ prolapse $1,420,200
University of California, San Francisco Brian Feeley Quest – Discovery Stage Research Projects Matrix Assisted Cell Transplantation of Promyogenic Fibroadipogenic Progenitor (FAP) Stem Cells $1,179,478
University of California, Los Angeles Prof. Song Li Quest – Discovery Stage Research Projects iPSC Extracellular Vesicles for Diabetes Therapy $1,354,928
Scripps Health Dr. Darryl D. D’Lima Quest – Discovery Stage Research Projects Meniscal Repair and Regeneration $1,361,775
The Stone Research Foundation for Sports Medicine and Arthritis Dr. Kevin Stone Quest – Discovery Stage Research Projects A Novel Therapy for Articular Cartilage Autologous Cellular Repair by Paste Grafting $1,180,309
University of California, San Diego Gene Wei-Ming Yeo Quest – Discovery Stage Research Projects RNA-directed therapy for Huntington’s disease $1,253,110
University of California, Irvine Dr. Mathew Mark Blurton-Jones Quest – Discovery Stage Research Projects Transplantation of genetically corrected iPSC-microglia for the treatment of Sanfilippo Syndrome (MPSIIIA) $1,083,379
University of California, San Francisco Dr. Julie Deane Saba Quest – Discovery Stage Research Projects Providing a cure for sphingosine phosphate lyase insufficiency syndrome (SPLIS) through adeno-associated viral mediated SGPL1 gene therapy $1,463,400
Scripps Research Institute Luke L Lairson Quest – Discovery Stage Research Projects Improving the efficacy and tolerability of clinically validated remyelination-inducing molecules using developable combinations of approved drugs $1,554,126
University of California, San Francisco Dr Julia Carnevale Quest – Discovery Stage Research Projects Generating deeper and more durable BCMA CAR T cell responses in Multiple Myeloma through non-viral knockin/knockout multiplexed genome engineering $1,463,368
Stanford University Dr. Sarah C Heilshorn Quest – Discovery Stage Research Projects Injectable, autologous iPSC-based therapy for spinal cord injury $789,000
Navega Therapeutics Ana Maria Moreno Quest – Discovery Stage Research Projects Optimization of a gene therapy for inherited erythromelalgia in iPSC-derived neurons $1,157,313
Cedars-Sinai Medical Center Dr Eduardo Marban Quest – Discovery Stage Research Projects New noncoding RNA chemical entity for heart failure with preserved ejection fraction. $1,397,412
Stanford University Dr. Stanley Qi Quest – Discovery Stage Research Projects A novel hybrid CRISPR tool for gene network perturbation and hiPSC engineering $704,661
University of California, San Diego Ziwei Huang Quest – Discovery Stage Research Projects Development of a new therapeutic for directing target specific stem cell migration and treatment $1,129,512
University of California, San Diego Dan S Kaufman Quest – Discovery Stage Research Projects Human iPSC-derived chimeric antigen receptor expressing macrophages for improved cancer treatment. $1,256,332
Stanford University Dr. Marius Wernig MD, PhD Quest – Discovery Stage Research Projects A universally applicable skin sheet for Dystrophic Epidermolysis Bullosa via next-generation gene editing, iPS cell technology and tissue engineering $1,229,040
University of California, Davis Dr. David J Segal PhD Quest – Discovery Stage Research Projects AAV9-Cas13 gene therapy for Angelman syndrome $1,364,903
Stanford University Dr. Phillip C Yang Quest – Discovery Stage Research Projects Hypoxia-specific Production of Exosomes from iPSC-derivatives for Myocardial Repair $1,418,023
Stanford University Kathleen M Sakamoto Quest – Discovery Stage Research Projects Small Molecules to inhibit Nemo-like Kinase for Treatment of Diamond Blackfan Anemia $846,638
University of California, Irvine Munjal M Acharya Quest – Discovery Stage Research Projects Stem cell-derived extracellular vesicles to reverse radiation-induced brain injury $1,064,108
University of California, San Francisco Dr Marisa Medina Quest – Discovery Stage Research Projects iPSCs as a screening tool to predict risk of nonalcoholic fatty liver disease $813,000
University of California, San Diego Dr. Tannishtha Reya Quest – Discovery Stage Research Projects Targeting Critical Regulators of Cancer Stem Cells $1,148,264
University of California, Davis Dr. Deborah K Lieu Quest – Discovery Stage Research Projects Building a hiPSC-based biopacemaker $1,260,827
City of Hope, Beckman Research Institute Professor Yanhong Shi Quest – Discovery Stage Research Projects Combating COVID-19 using human PSC-derived NK cells $249,998
University of California, San Diego Tariq M Rana Quest – Discovery Stage Research Projects Development of COVID-19 Antiviral Therapy Using Human iPSC-Derived Lung Organoids $250,000
University of California, Los Angeles Dr. Thomas Carmichael M.D., Ph.D. Quest – Discovery Stage Research Projects Human-induced pluripotent stem cell-derived glial enriched progenitors to treat white matter stroke and vascular dementia. $250,000
University of California, Irvine Robert F. Hunt Quest – Discovery Stage Research Projects Optimization of a human interneuron cell therapy for traumatic brain injury $240,000
University of Southern California Dr. Justin K Ichida Quest – Discovery Stage Research Projects Development of a SYF2 antisense oligonucleotide (ASO) treatment for ALS $222,300
University of California, Irvine Dr. Mathew Mark Blurton-Jones Quest – Discovery Stage Research Projects Transplantation of Pluripotent Stem Cell Derived Microglia for the Treatment of Adult-onset Leukoencephalopathy (HDLS/ALSP) $214,668
Vitabolus, Inc. Aline Betancourt Quest – Discovery Stage Research Projects The First Orally Delivered Cell Therapy for the Treatment of Inflammatory Bowel Disease $249,000
Lundquist Institute for Biomedical Innovation at Harbor – UCLA Medical Center Dr Eiji Yoshihara PhD Quest – Discovery Stage Research Projects Dual angiogenic and immunomodulating nanotechnology for subcutaneous stem cell derived islet transplantation for the treatment of diabetes $250,000
University of California, Los Angeles Dr. Donald B. Kohn PhD Quest – Discovery Stage Research Projects Hematopoietic Stem Cell Gene Therapy for X-linked Agammaglobulinemia $219,230
University of California, San Diego Dan S Kaufman Quest – Discovery Stage Research Projects Human iPSC-derived chimeric antigen receptor-expressing macrophages for cancer treatment $222,200
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