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Institution Researcher name Grant Type Grant Title Award Value
Stanford University Dr. Bertha Chen Quest – Discovery Stage Research Projects iPSC-derived smooth muscle cell progenitor conditioned medium for treatment of pelvic organ prolapse $1,420,200
University of California, San Francisco Brian Feeley Quest – Discovery Stage Research Projects Matrix Assisted Cell Transplantation of Promyogenic Fibroadipogenic Progenitor (FAP) Stem Cells $1,179,478
Scripps Health Dr. Darryl D. D’Lima Quest – Discovery Stage Research Projects Meniscal Repair and Regeneration $1,361,775
The Stone Research Foundation for Sports Medicine and Arthritis Dr. Kevin Stone Quest – Discovery Stage Research Projects A Novel Therapy for Articular Cartilage Autologous Cellular Repair by Paste Grafting $1,180,309
University of California, San Francisco Dr. Julie Deane Saba Quest – Discovery Stage Research Projects Providing a cure for sphingosine phosphate lyase insufficiency syndrome (SPLIS) through adeno-associated viral mediated SGPL1 gene therapy $1,463,400
Scripps Research Institute Luke L Lairson Quest – Discovery Stage Research Projects Improving the efficacy and tolerability of clinically validated remyelination-inducing molecules using developable combinations of approved drugs $1,554,126
University of California, San Francisco Dr Julia Carnevale Quest – Discovery Stage Research Projects Generating deeper and more durable BCMA CAR T cell responses in Multiple Myeloma through non-viral knockin/knockout multiplexed genome engineering $1,463,368
Stanford University Dr. Sarah C Heilshorn Quest – Discovery Stage Research Projects Injectable, autologous iPSC-based therapy for spinal cord injury $789,000
Navega Therapeutics Ana Maria Moreno Quest – Discovery Stage Research Projects Optimization of a gene therapy for inherited erythromelalgia in iPSC-derived neurons $1,157,313
Stanford University Dr. Stanley Qi Quest – Discovery Stage Research Projects A novel hybrid CRISPR tool for gene network perturbation and hiPSC engineering $704,661
University of California, San Diego Ziwei Huang Quest – Discovery Stage Research Projects Development of a new therapeutic for directing target specific stem cell migration and treatment $1,129,512
Stanford University Dr. Marius Wernig MD, PhD Quest – Discovery Stage Research Projects A universally applicable skin sheet for Dystrophic Epidermolysis Bullosa via next-generation gene editing, iPS cell technology and tissue engineering $1,229,040
Stanford University Dr. Phillip C Yang Quest – Discovery Stage Research Projects Hypoxia-specific Production of Exosomes from iPSC-derivatives for Myocardial Repair $1,418,023
University of California, Davis Dr. Deborah K Lieu Quest – Discovery Stage Research Projects Building a hiPSC-based biopacemaker $1,260,827
Children’s Hospital of Los Angeles Dr. Mark R Frey Quest – Discovery Stage Research Projects Universal Pluripotent Liver Failure Therapy (UPLiFT) $1,297,512
HEALIOS NA, Inc. Dr. Norihiro Tsuneyoshi Tool Translational Research Projects Generation of human universal donor iPS cells $999,989
Defined Bioscience, Inc. Steven Douglas Rees Tool Translational Research Projects Development of a low-cost, clinical-grade iPS maintenance medium for enabling stem cell therapy manufacturing $999,848
University of California, Davis Dr Jan A Nolta Tool Translational Research Projects T-Pure: Peripheral Blood Processing Tool for Point of Care CAR-T Manufacturing $1,217,954
Greenstone Biosciences, Inc. Paul D Pang Tool Translational Research Projects Cell Villages and Clinical Trial in a Dish with Pooled iPSC-CMs for Drug Discovery $1,350,000
Organos, Inc. Samuel Wall Tool Translational Research Projects Human iPSC-derived micro-heart muscles for high-throughput cardiac drug discovery $1,119,382
University of California, Davis Aijun Wang PhD Medical Device Translational Research Projects Living Synthetic Vascular Grafts with Renewable Endothelium $3,082,579
Axent Biosciences Inc. Abhay Joshi Therapeutic Translational Research Projects A high quality, accessible cell therapy for Parkinson’s Disease produced in a scalable bioreactor system for 3D cell expansion and differentiation $3,999,241
University of California, San Francisco Sarah Monica Knox Therapeutic Translational Research Projects Neurogenic hydrogel stimulation of stem cells to regenerate radiation-damaged salivary glands $2,312,021
Ray Therapeutics, INC Paul Bresge Therapeutic Translational Research Projects Optogenetic Therapy for Treatment of Geographic Atrophy $3,998,930
Siren Biotechnology, Inc. Dr. Nicole K Paulk Therapeutic Translational Research Projects Development of an AAV gene therapy immunotherapy for the treatment of glioblastoma $3,997,919
University of California, San Diego Dr Karen Christman Therapeutic Translational Research Projects Pro-regenerative infusible ECM biomaterial for treating acute myocardial infarction $4,353,438
Cedars-Sinai Medical Center Dr. Ahmed Gamal Ibrahim Therapeutic Translational Research Projects Noncoding RNA drug TY1 as a therapeutic candidate for scleroderma and systemic sclerosis $2,590,224
University of California, Los Angeles Zulema Romero Garcia Therapeutic Translational Research Projects Adenine Base Editing for Autologous Hematopoietic Stem Cell Gene Therapy of CD3δ SCID $5,966,928
University of California, San Diego Dr. Eric D. Adler MD Therapeutic Translational Research Projects Ex Vivo Modified Hematopoietic Stem Cells to Treat Danon Disease $5,180,389
University of California, Los Angeles Dr. Donald B Kohn Therapeutic Translational Research Projects Hematopoietic Stem Cell Gene Editing for X-linked Agammaglobulinemia (XLA) $4,309,973
University of California, Los Angeles Dr. Gerald Lipshutz DDS, MD, MS Therapeutic Translational Research Projects Development of a Gene Therapy for the Treatment of Arginase Deficiency – Translating from Proof of Concept to Support Pre-IND Meeting $5,266,504
City of Hope, Beckman Research Institute Dr Michael A. Caligiuri Therapeutic Translational Research Projects Targeting multiple myeloma with BCMA-CAR NK cells expressing a GPRC5D-NKG2D bispecific antibody $6,036,001
ImmunoVec Luke Riggan Therapeutic Translational Research Projects Hematopoietic Stem Cell Gene Therapy for Wiskott Aldrich Syndrome $3,999,899
University of California, Los Angeles Anthony J Aldave Therapeutic Translational Research Projects AAV Gene Therapy for Treating Congenital Hereditary Endothelial Dystrophy associated with Biallelic SLC4A11 Mutations $4,338,166
BrainXell Therapeutics Maria Daniela Cirnaru Therapeutic Translational Research Projects Development of Autologous Cell Replacement Therapy for Parkinson’s Disease: Path to Personalized Treatment $3,841,110
University of California, Los Angeles Dr. Sophie X Deng Therapeutic Translational Research Projects Extracellular Vesicle-Based Therapy for Corneal Scars $5,779,276
Rejuvenation Technologies, Inc. John Ramunas Therapeutic Translational Research Projects Telomerase mRNA for short telomere related pulmonary fibrosis $3,984,942
University of California, Los Angeles Dr. Scott G Kitchen Therapeutic Translational Research Projects Hematopoietic Stem/Progenitor Cell-Based Chimeric Antigen Receptor Gene Therapy for HIV Infection $6,140,723
University of Southern California Dr. Rongfu Wang Therapeutic Translational Research Projects Novel T cell receptor-STEM T cell immunotherapy in lung cancer $5,689,540
Stanford University Walter Park Therapeutic Translational Research Projects Enhanced Autologous Pancreatic Islet Transplantation and Survival for Diabetes Mellitus Therapy $6,054,165
City of Hope, Beckman Research Institute Dr Jianhua Yu Therapeutic Translational Research Projects Specific Targeting Hypoxia Metastatic Breast Tumor with Allogeneic Off-the-Shelf Anti-EGFR CAR NK Cells Expressing an ODD domain of HIF-1α $6,036,002
VxBiosciences inc. Dr. Christina Chuong Therapeutic Translational Research Projects Escape-Resistant Oligonucleotide Therapy (ONT) for Cytomegalovirus (CMV) Disease in Hematopoietic Stem-Cell and Solid-Organ Transplant Patients $3,977,180
Mahzi Therapeutics Dr. Allyson Berent Therapeutic Translational Research Projects Development of a Gene Therapy for the Treatment of Pitt Hopkins Syndrome (PHS) – Translating from Animal Proof of Concept to Support Pre-IND Meeting $3,800,760
University of California, Davis Dr. William J Murphy Therapeutic Translational Research Projects Overcoming resistance to standard CD19-targeted CAR T using a novel triple antigen targeted vector $3,869,061
University of California, San Diego Stephanie Cherqui Therapeutic Translational Research Projects CRISPR/Cas9-mediated gene editing of Hematopoietic stem and progenitor cells for Friedreich’s ataxia $4,846,579
University of California, Los Angeles Dr. Donald B. Kohn PhD Therapeutic Translational Research Projects Autologous MPO Knock-Out Hematopoietic Stem and Progenitor Cells for Pulmonary Arterial Hypertension $4,751,297
University of Southern California Preet M Chaudhary Therapeutic Translational Research Projects Next generation affinity-tuned CAR for prostate cancer $5,805,144
University of California, Irvine Dr. Aileen J Anderson Therapeutic Translational Research Projects A human neural stem cell therapeutic candidate for the treatment of chronic cervical spinal cord injury $4,950,024
University of California, San Francisco Arun P Wiita Therapeutic Translational Research Projects CD72 nanoCARs for the treatment of refractory pediatric B-cell acute lymphoblastic leukemia $3,330,801
MyoGene Bio LLC Dr Courtney Young Therapeutic Translational Research Projects Development of MyoDys45-55, a gene editing therapy for Duchenne muscular dystrophy $3,400,000