Our Grants

CIRM provides funding across five key areas: Infrastructure, Education, Discovery Research, Translational Research, and Clinical Research. By supporting projects at every stage of development, from initial discovery to clinical trials, CIRM drives progress in regenerative medicine and accelerates innovative therapies to patients.

Check out our portfolio of awards below. Click here to see a list of People We’ve Funded. Click here to see a list of our Funded Institutions.

All CIRM Grants

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Institution Researcher name Grant Type Grant Title Award Value
Stanford University Dr. Matthew H Porteus Clinical Trial Stage Projects Phase 1/1b study of T-allo10 infusion after HLA-partially matched abdepleted-HSCT in children and young adults with hematologic malignancies. $10,563,822
Stanford University Dr. Gary Steinberg Clinical Trial Stage Projects Safety and Tolerability Study of Neural Stem Cells (NR1) in Subjects with Chronic Ischemic Subcortical Stroke $11,998,988
Cedars-Sinai Medical Center Professor Clive Niels Svendsen Clinical Trial Stage Projects CNS10-NPC-GDNF delivered into the motor cortex for the treatment of ALS $11,990,372
City of Hope, Beckman Research Institute Dr. Leo D Wang Clinical Trial Stage Projects Phase I Study of IL13Rα2-Targeting CAR T Cells After Lymphodepletion for Children with Refractory or Recurrent Malignant Brain Tumors $8,401,309
University of California, San Francisco Steven G. Deeks Clinical Trial Stage Projects Anti-HIV duoCAR-T cell therapy for HIV infection $8,970,732
University of California, Los Angeles Dr. Sophie X Deng Clinical Trial Stage Projects Safety and Feasibility of Cultivated Autologous Limbal Stem Cells for Limbal Stem Cell Deficiency $10,301,486
Cedars-Sinai Medical Center Professor Clive Niels Svendsen Clinical Trial Stage Projects Clinical Study to Assess Safety and Efficacy of Subretinal Injection of Human Neural Progenitor Cells for Treatment of Retinitis Pigmentosa $5,325,603
City of Hope, Beckman Research Institute Dr Jana Portnow Clinical Trial Stage Projects A Phase I Study of Chimeric Antigen Receptor Engineered Stem/Memory T Cells for the Treatment of HER2-Positive Brain Metastases $8,040,000
University of California, San Diego Dr. Stephanie Cherqui Clinical Trial Stage Projects Phase 1/2 study for autologous human CD34+ hematopoietic stem cells ex vivo transduced with pCCL-CTNS lentiviral vector for treatment of Cystinosis. $11,999,944
University of California, San Francisco Peter Stock Clinical Trial Stage Projects Pancreatic Islets and Parathyroid Gland Co-transplantation for Treatment of Diabetes in the Intra-Muscular Site: PARADIGM $7,913,768
Stanford University Dr. Everett H. Meyer Clinical Trial Stage Projects Induction of Tolerance by Combinatorial Therapy w/ Donor Stem Cells and Expanded Recipient Treg cells in HLA-mismatched Kidney Transplant Recipients $8,920,000
Stanford University Robert Lowsky Clinical Trial Stage Projects Induction of Tolerance to Combined Kidney and Hematopoietic Progenitor Cell Transplants from HLA Haplotype Matched Living Donors $6,653,266
University of California, Los Angeles Dr. Donald B. Kohn Clinical Trial Stage Projects Efficacy and safety of cryopreserved autologous CD34+ HSC transduced with EFS lentiviral vector encoding for human ADA gene in ADA-SCID subjects $5,827,000
Cure Rare Disease Dr. Susan Perlman Late Stage Preclinical Projects Advancing a novel antisense oligonucleotide for the treatment of SCA3, a devastating neurodegenerative disease $5,692,538
University of California, Davis Dr. Joseph S Anderson Late Stage Preclinical Projects Expression of Ube3a by the hematopoietic system for the treatment of Angelman syndrome $4,487,656
Rejuvenate Bio Noah Davidsohn Late Stage Preclinical Projects Novel Gene Therapy Targeting Multiple Pathological Drivers of Desmoplakin Associated Arrhythmogenic Cardiomyopathy $570,000
Amplo Biotechnology Patricio Sepulveda Late Stage Preclinical Projects Targeted DOK7 gene therapy for Congenital Myasthenic Syndromes $2,894,305
University of California, San Diego Mark H Tuszynski Late Stage Preclinical Projects Human Embryonic Stem Cell-Derived Neural Stem Cells for Severe Spinal Cord Injury (SCI) $6,000,000
University of California, Los Angeles Arjun Deb Late Stage Preclinical Projects Development of a therapeutic monoclonal antibody for the treatment of myocardial infarction and heart failure $5,999,998
Children’s Hospital of Los Angeles Shahab Asgharzadeh Late Stage Preclinical Projects Chimeric TGFB Signaling Receptor (CTSR) Enabled Anti-B7H3 CAR T-cell Therapy in Children and AYA with Recurrent Solid Tumors $6,000,000
University of California, San Francisco Thomas Martin Late Stage Preclinical Projects A 1XX-enhanced and fully non-viral BCMA CAR T cell therapy for Relapsed and Refractory Multiple Myeloma (UCCT-BCMA-1) $4,585,501
Elpida Therapeutics Mr Terry Pirovolakis Late Stage Preclinical Projects Pre-Clinical To Clinical Gene Therapy Development For CMT4J $3,930,964
Cedars-Sinai Medical Center Dr. Eugenio Cingolani Late Stage Preclinical Projects Extracellular Vesicles for Ventricular Tachycardia $1,050,000
City of Hope, Beckman Research Institute Prof. Karen S Aboody M.D. Late Stage Preclinical Projects Neural stem cell delivered CRAd-S-pk7 oncolytic viro-immunotherapy for ovarian cancer $5,314,547
Mahzi Therapeutics Dr. Yael Weiss Late Stage Preclinical Projects Development of a Gene Therapy for the Treatment of WWOX related epileptic encephalopathy (WOREE) $4,000,000
University of California, Davis Dr Mehrdad Abedi Late Stage Preclinical Projects Superior forward-oriented b-globin vector for treating Sickle Cell Disease $4,598,398
University of Southern California Mark Salman Humayun Late Stage Preclinical Projects IND-enabling program for PRPE-SF, the secretome from polarized stem cell-derived RPE cells, for the treatment of dry-age related macular degeneration $5,993,562
Stanford University Dr. Matthew H Porteus Late Stage Preclinical Projects Autologous Gene Corrected Sinus Basal Cells to Treat Serious Cystic Fibrosis Sinus Disease $6,000,000
University of California, Irvine Kyriacos A Athanasiou Late Stage Preclinical Projects Treatment of the TMJ disc complex $6,000,000
Aspera Biomedicines, Inc Catriona Jamieson Late Stage Preclinical Projects Cancer Stem Cell Interception with Rebecsinib: A First-in-Class ADAR1 Inhibitor $3,200,000
University of California, Los Angeles Dr. Jerome A. Zack Ph.D. Late Stage Preclinical Projects Clinical Translation of Autologous Regenerative Pluripotent Stem Cell Therapy for Blindness $6,000,000
Rampart Bioscience Jeffrey Bartlett Late Stage Preclinical Projects Ex vivo Engineering of Autologous Hematopoietic Stem Cells for the Treatment of Hypophosphatasia $3,999,980
Ossium Health, Inc. Dr. Brian Johnstone Late Stage Preclinical Projects Development of OSSM-007, cryopreserved interferon-gamma primed allogeneic MSCs, for treatment of steroid refractory acute graft versus host disease $3,457,858
University of California, Davis Dr. Joseph S Anderson Late Stage Preclinical Projects Hematopoetic stem cell gene therapy for the treatment of Tay-Sachs disease $3,998,253
Stanford University Natalia Gomez-Ospina Late Stage Preclinical Projects Genome Editing of Autologous Hematopoietic Stem Cells to Treat Severe Mucopolysaccharidosis type 1 (Hurler Syndrome) $5,444,353
University of California, San Francisco Dr. Karin Lindgren Gaensler Late Stage Preclinical Projects Development of TriLeukeVax, an Engineered Autologous Leukemia Vaccine for Stimulating Cytolytic Immune Responses to Residual Leukemic Stem Cells $6,000,000
ImmunoVec Dr. Ryan L. Wong Late Stage Preclinical Projects Hematopoietic Stem Cell Gene Therapy for XCGD $3,999,959
University of California, Los Angeles Dr. Antoni Ribas MD/PhD Late Stage Preclinical Projects Skin regeneration and wound healing with a topical BRAF inhibitor $5,005,126
University of Southern California Dr. Denis A Evseenko Dr. Late Stage Preclinical Projects Plurocart: a novel stem cell-based implant for articular cartilage restoration $5,999,782
University of California, Irvine Dr. LESLIE M Thompson Late Stage Preclinical Projects An hESC-derived hNSC Therapeutic for Huntington’s Disease $5,635,393
University of California, Los Angeles Dr. Donald B. Kohn Disease Team Therapy Development III Clinical Trial of Stem Cell Gene Therapy for Sickle Cell Disease $10,351,535
Stanford University Xiaojie Qiu Foundation – Discovery Stage Research Projects Mapping and modeling endothelial cell fate decisions for pulmonary arterial hypertension $1,540,798
Gladstone Institutes, J. David Dr. Steve M. Finkbeiner Foundation – Discovery Stage Research Projects Lewy body dementia, 𝛼-synuclein, and cell-specific mechanisms of neurodegeneration $1,739,760
Minutia, Inc. Katy Digovich Foundation – Discovery Stage Research Projects Immune cloaking of human stem cell-derived insulin-producing cells for curative cell therapy without immunosuppression $1,192,586
University of California, San Francisco Tomasz Nowakowski Foundation – Discovery Stage Research Projects Neuroimmune interactions in the developing human brain $1,626,000
University of California, San Diego Dr Marianna Alperin Foundation – Discovery Stage Research Projects Harnessing the rejuvenating capacity of pregnancy-associated factors to restore aged stem cell function $1,539,520
University of California, Los Angeles Dr. M. Carrie Miceli Foundation – Discovery Stage Research Projects Interrogating Satellite Cell and Myofiber Defects and Repair in Human DMD using Single Nuclei/Single Cell RNA Sequencing of Muscle Resident Cells $1,578,000
Sanford Burnham Prebys Medical Discovery Institute Ani Deshpande Foundation – Discovery Stage Research Projects Investigating the SGF29/SAGA complex in regulation of normal and cancer stem cells $1,547,999
Cedars-Sinai Medical Center Tyler Mark Pierson Foundation – Discovery Stage Research Projects Modeling of GATAD2B-associated neurodevelopmental disorder and NuRDopathies: Investigation of cellular & molecular anomalies altering neurodevelopment $1,318,441
University of California, Los Angeles Michael F Wells Foundation – Discovery Stage Research Projects Village-based identification of human risk factors for viral neuropathogenesis $1,577,448

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