All CIRM Grants

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Institution Researcher name Grant Type Grant Title Award Value
Stanford University Jeffrey L Goldberg Inception – Discovery Stage Research Projects Embryonic Stem Cells for Corneal Endothelial Degeneration $235,836
University of California, Los Angeles Dr. Owen N Witte M.D. Inception – Discovery Stage Research Projects Identification of stem cell surface markers as potential therapeutic targets for advanced prostate cancer $209,160
University of California, San Diego Professor Alysson R Muotri Inception – Discovery Stage Research Projects Reverse transcriptase inhibitors as a novel therapeutic approach for neurological autoimmune disorders $210,060
University of California, Los Angeles Dr. April Pyle Ph.D. Inception – Discovery Stage Research Projects Novel Platforms to Enhance In Vivo Delivery of Skeletal Muscle Progenitor Cells from Human Pluripotent Stem Cells $230,400
University of California, Los Angeles Dr. Bennett G Novitch Ph.D. Inception – Discovery Stage Research Projects Organoid Modeling of Human Cortical Microcircuits $208,916
Cedars-Sinai Medical Center Professor Clive Niels Svendsen Inception – Discovery Stage Research Projects Blood Brain Barrier (BBB)-on-Chip: Development and validation of a novel iPS-based microfluidic model of the human BBB $241,992
University of California, San Francisco Dr. Holger F Willenbring Inception – Discovery Stage Research Projects Generation of bile duct-competent transplantable human liver organoids $206,460
University of California, Los Angeles Dr. Arjun Deb Inception – Discovery Stage Research Projects Targeting progenitors in scar tissue to reduce chronic scar burden $230,400
University of California, Berkeley Dr. Jacob Ellery Corn Ph.D Inception – Discovery Stage Research Projects Genome editing for causation and reversion of MPN-associated mutations in human hematopoietic stem cells $235,800
Stanford University Dr. Philip Arden Beachy PhD Inception – Discovery Stage Research Projects Curing bladder cancer by replacing corrupted urothelium with differentiated hES cells $210,906
University of California, San Diego Dionicio Siegel Inception – Discovery Stage Research Projects New Methods for the Chemical Expansion of Hematopoietic Stem and Progenitor Cells $232,200
Stanford University Dr. Bertha Chen Inception – Discovery Stage Research Projects Autologous iPSC-based therapy for radiation induced bladder injury $235,836
University of California, Los Angeles Dr. Thomas Carmichael M.D., Ph.D. Inception – Discovery Stage Research Projects iPS-Interneuron Transplantation for Neural Repair after Stroke $229,396
University of California, San Diego Karl Karl J. Wahlin Inception – Discovery Stage Research Projects Microenvironment based optimization of retinal induction using CRISPR-CAS9 reporter pluripotent stem cells as an expandable source of retinal progenitors and photoreceptors. $232,200
University of California, San Francisco Andrew Stephen Brack Inception – Discovery Stage Research Projects Examining the efficacy of GDF11 antibody as a rejuvenator of aged human muscle stem cell capacity and muscle repair . $180,000
Stanford University Dr. Phillip C Yang Inception – Discovery Stage Research Projects Activation of patient-specific endogenous myocardial repair through the exosomes generated from the hypoxic iPSC-derived cardiomyocytes (iCMs). $234,619
Cedars-Sinai Medical Center Linda Cambier Inception – Discovery Stage Research Projects Exosomal Y-RNAs as mediators of bioactivity of cardiac-derived cell therapy $181,063
Stanford University Professor Irving L Weissman MD Tool Translational Research Projects Purification of Human Hematopoietic Stem Cells (HSCs) for Clinical Stem Cell Transplantation $1,347,722
Defined Bioscience, Inc. Steven Douglas Rees Tool Translational Research Projects Development of a low-cost, clinical-grade iPS maintenance medium for enabling stem cell therapy manufacturing $999,848
HEALIOS NA, Inc. Dr. Norihiro Tsuneyoshi Tool Translational Research Projects Generation of human universal donor iPS cells $999,989
University of California, Davis Dr Jan A Nolta Tool Translational Research Projects T-Pure: Peripheral Blood Processing Tool for Point of Care CAR-T Manufacturing $1,217,954
Greenstone Biosciences, Inc. Paul D Pang Tool Translational Research Projects Cell Villages and Clinical Trial in a Dish with Pooled iPSC-CMs for Drug Discovery $1,350,000
Organos, Inc. Samuel Wall Tool Translational Research Projects Human iPSC-derived micro-heart muscles for high-throughput cardiac drug discovery $1,119,382
Stanford University Dr. Joseph C. Wu Tool Translational Research Projects A Novel, Robust and Comprehensive Predictive Tool Using Human Disease-Specific Induced Pluripotent Stem Cells for Preclinical Drug Screening $975,000
University of California, Davis Aijun Wang PhD Medical Device Translational Research Projects Living Synthetic Vascular Grafts with Renewable Endothelium $3,082,579
Cedars-Sinai Medical Center Yuan Yuan Diagnostic Translational Research Projects A Rapid Clinical Digital Patient-derived Organoid to Guide Breast Cancer Treatment Decision $1,535,375
University of California, San Francisco Dr. Steven Mack PhD Diagnostic Translational Research Projects Development of a Noninvasive Prenatal Test for Beta-Hemoglobinopathies for Earlier Stem Cell Therapeutic Interventions $633,014
UCSF Benioff Children’s Hospital Oakland Dr. Henry A. Erlich Ph.D. Diagnostic Translational Research Projects Development of a Noninvasive Prenatal Test for Beta-Hemoglobinopathies for Earlier Stem Cell Therapeutic Interventions $1,074,177
Neurona Therapeutics Dr. Cory R Nicholas Therapeutic Translational Research Projects Development of a universal allogeneic human interneuron cell therapy candidate for the treatment of drug resistant focal epilepsy. $3,828,714
City of Hope, Beckman Research Institute Lei Tian Therapeutic Translational Research Projects Targeting pancreatic cancer with Allogeneic Off-the-Shelf PSCA-CAR NK cells $6,036,000
University of California, Los Angeles Dr. Lili Yang Therapeutic Translational Research Projects Combating Ovarian Cancer with Stem Cell-Engineered Off-The-Shelf CAR-NKT Cell Therapy $5,601,600
Stanford University Natalia Gomez-Ospina Therapeutic Translational Research Projects Toward a Cure for Gaucher Disease Type 1: Autologous Transplantation of Genome Edited Hematopoietic Stem Cells $4,696,296
Replay Holdings, Inc Anthony Conway Therapeutic Translational Research Projects Hypoimmunogenic iPSC-derived TCR-NK cells for oncology $4,107,571
AcuraStem Incorporated Mr. Samuel V. Alworth MS, MBA Therapeutic Translational Research Projects Development of AS-241, an UNC13A Targeting Antisense Oligonucleotide (ASO) Treatment for ALS, for IND-enabling Studies $4,012,325
Axent Biosciences Inc. Abhay Joshi Therapeutic Translational Research Projects A high quality, accessible cell therapy for Parkinson’s Disease produced in a scalable bioreactor system for 3D cell expansion and differentiation $3,999,241
University of California, Los Angeles Dr. Gerald Lipshutz DDS, MD, MS Therapeutic Translational Research Projects Development of a Gene Therapy for Treatment of Guanidinoacetate Methyltransferase Deficiency-Translating In Vivo Proof of Concept to Support a Pre-IND $5,145,825
Ray Therapeutics, INC Paul Bresge Therapeutic Translational Research Projects Optogenetic Therapy for Treatment of Geographic Atrophy $3,998,930
University of California, San Francisco Sarah Monica Knox Therapeutic Translational Research Projects Neurogenic hydrogel stimulation of stem cells to regenerate radiation-damaged salivary glands $2,312,021
Siren Biotechnology, Inc. Dr. Nicole K Paulk Therapeutic Translational Research Projects Development of an AAV gene therapy immunotherapy for the treatment of glioblastoma $3,997,919
Cedars-Sinai Medical Center Dr. Ahmed Gamal Ibrahim Therapeutic Translational Research Projects Noncoding RNA drug TY1 as a therapeutic candidate for scleroderma and systemic sclerosis $2,590,224
University of California, San Diego Dr Karen Christman Therapeutic Translational Research Projects Pro-regenerative infusible ECM biomaterial for treating acute myocardial infarction $4,353,438
University of California, Los Angeles Zulema Romero Garcia Therapeutic Translational Research Projects Adenine Base Editing for Autologous Hematopoietic Stem Cell Gene Therapy of CD3δ SCID $5,966,928
University of California, Los Angeles Dr. Donald B Kohn Therapeutic Translational Research Projects Hematopoietic Stem Cell Gene Editing for X-linked Agammaglobulinemia (XLA) $4,309,973
University of California, San Diego Dr. Eric D. Adler MD Therapeutic Translational Research Projects Ex Vivo Modified Hematopoietic Stem Cells to Treat Danon Disease $5,180,389
University of California, Los Angeles Dr. Gerald Lipshutz DDS, MD, MS Therapeutic Translational Research Projects Development of a Gene Therapy for the Treatment of Arginase Deficiency – Translating from Proof of Concept to Support Pre-IND Meeting $5,266,504
City of Hope, Beckman Research Institute Dr Michael A. Caligiuri Therapeutic Translational Research Projects Targeting multiple myeloma with BCMA-CAR NK cells expressing a GPRC5D-NKG2D bispecific antibody $6,036,001
University of California, Los Angeles Anthony J Aldave Therapeutic Translational Research Projects AAV Gene Therapy for Treating Congenital Hereditary Endothelial Dystrophy associated with Biallelic SLC4A11 Mutations $4,338,166
ImmunoVec Luke Riggan Therapeutic Translational Research Projects Hematopoietic Stem Cell Gene Therapy for Wiskott Aldrich Syndrome $3,999,899
BrainXell Therapeutics Maria Daniela Cirnaru Therapeutic Translational Research Projects Development of Autologous Cell Replacement Therapy for Parkinson’s Disease: Path to Personalized Treatment $3,841,110
University of California, Los Angeles Dr. Sophie X Deng Therapeutic Translational Research Projects Extracellular Vesicle-Based Therapy for Corneal Scars $5,779,276
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