CIRM provides funding across five key areas: Infrastructure, Education, Discovery Research, Translational Research, and Clinical Research. By supporting projects at every stage of development, from initial discovery to clinical trials, CIRM drives progress in regenerative medicine and accelerates innovative therapies to patients.
Check out our portfolio of awards below.
All CIRM Grants
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| Institution |
Researcher name |
Grant Type |
Grant Title |
Award Value |
| Rocket Pharmaceuticals, Inc. |
Dr. Jonathan Schwartz |
Clinical Trial Stage Projects |
A Phase 2 Study Evaluating the Efficacy and Safety of IV Administered rAAV9 Vector Containing RP-A501 in Male Patients with Danon Disease |
$5,808,735 |
| University of California, Davis |
Dr. Diana L. Farmer |
Clinical Trial Stage Projects |
The CuRe Trial: Cellular Therapy for In Utero Repair of Myelomeningocele |
$8,996,477 |
| Stanford University |
Dr. Reena Parada Thomas |
Clinical Trial Stage Projects |
Phase I Trial of Locoregionally Delivered Autologous B7-H3 CAR T Cells (B7-H3CART) in Adults with Recurrent Glioblastoma Multiforme |
$11,999,991 |
| City of Hope, Beckman Research Institute |
Elizabeth Budde |
Clinical Trial Stage Projects |
Phase I Study of Chimeric Antigen Receptor Engineered T Cells targeting CD33 for the Treatment of Relapsed/Refractory Acute Myeloid Leukemia |
$11,983,547 |
| University of California, San Diego |
Prof. Olivia Kim-McManus |
Clinical Trial Stage Projects |
Personalized antisense oligonucleotide therapy for rare pediatric genetic disease: SCN2A |
$960,713 |
| Stanford University |
Anusha Kalbasi |
Clinical Trial Stage Projects |
Stem-Derived IL13Ra2 Chimeric Antigen Receptor T cells for Patients with Melanoma and Advanced Solid Tumors |
$10,211,085 |
| Regenerative Patch Technologies LLC |
Dr Jane S Lebkowski |
Clinical Trial Stage Projects |
A Phase 2b, Randomized, Assessor-Masked Clinical Trial to Assess the Safety and Efficacy of the CPCB-RPE1 Implant in Subjects with Geographic Atrophy |
$12,373,748 |
| City of Hope, Beckman Research Institute |
Dr. Angelo Manuel Almeida Cardoso Ph.D., MD |
Clinical Trial Stage Projects |
Evaluation of Safety and Feasibility of Cytomegalovirus-Specific, Anti-HIV Chimeric Antigen Receptor (CMV/HIV-CAR) T Cells in People with HIV |
$11,299,976 |
| Combangio, Inc. |
R. Kim Brazzell |
Clinical Trial Stage Projects |
Phase 2b Clinical Study of KPI-012 Topical Ophthalmic Human Mesenchymal Stem Cell Secretome for the Treatment of Persistent Corneal Epithelial Defect |
$15,000,000 |
| Immusoft Corporation |
Dr Robert Hayes |
Clinical Trial Stage Projects |
A Phase I Open Label Study to Evaluate the Safety and Tolerability of ISP-001 in Patients with Mucopolysaccharidosis Type 1 |
$8,000,000 |
| Eureka Therapeutics, Inc. |
Pei Wang |
Clinical Trial Stage Projects |
Autologous ARTEMIS® T Cells to Treat Refractory/Relapsed Pediatric Liver Cancer |
$10,600,072 |
| Stanford University |
Dr. Matthew H Porteus |
Clinical Trial Stage Projects |
Reduced intensity conditioning with JSP191 prior to TCRαβ+ T-cell/CD19+ B-cell depleted hematopoietic stem cell transplant for Fanconi Anemia patients |
$10,642,420 |
| Angiocrine Bioscience, Inc. |
Dr. Paul Finnegan |
Clinical Trial Stage Projects |
AB-205-301 Phase 3 Trial and Related Activities to Support Clinical Development of AB-205 |
$10,930,014 |
| Genascence Corporation |
Dr. Thomas W Chalberg Jr. |
Clinical Trial Stage Projects |
A Phase 1b, Randomized, Blinded, Placebo-Controlled Dose-Ranging Study of GNSC-001 Evaluating Safety, Pharmacodynamics, and Biomarkers in Knee OA |
$11,637,194 |
| Tachyon Therapeutics, Inc |
Ivan King |
Clinical Trial Stage Projects |
TACH101: A Potent, First-In-Class KDM4 Inhibitor for Advanced Cancers |
$6,862,609 |
| City of Hope, Beckman Research Institute |
Ryotaro Nakamura |
Clinical Trial Stage Projects |
Treatment of Severe Aplastic Anemia by induction of mixed chimerism using CD4+ T cell depleted haploidentical donor stem cell transplant |
$9,054,216 |
| Stanford University |
Alice Bertaina |
Clinical Trial Stage Projects |
Sequential same donor αβdepleted-HSCT from an HLA-partially matched donor allowing immunosuppression free kidney transplant |
$11,998,188 |
| Neurona Therapeutics |
Dr. Cory R Nicholas |
Clinical Trial Stage Projects |
Phase 1/2 Study of NRTX-1001 Neural Cell Therapy in Subjects with Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy |
$7,999,999 |
| Excision BioTherapeutics |
William Kennedy |
Clinical Trial Stage Projects |
Phase 1 Clinical research program for functional cure of HIV with EBT-101, in-vivo gene therapy |
$6,852,486 |
| Wake Forest University Health Sciences |
James Yoo |
Clinical Trial Stage Projects |
Phase I Treatment of Urethral Strictures in Humans |
$3,841,593 |
| Stanford University |
Dr. Rosa Bacchetta |
Clinical Trial Stage Projects |
Phase 1 Study of Autologous CD4LVFOXP3 in Participants with IPEX Syndrome |
$11,999,179 |
| City of Hope, Beckman Research Institute |
Dr Jana Portnow |
Clinical Trial Stage Projects |
A Phase I Study of Multiple doses of NSC-Based Oncolytic Virotherapy Administered Intracerebrally to Patients with Recurrent High-Grade Gliomas |
$11,999,984 |
| University of California, Davis |
Peter C Belafsky |
Clinical Trial Stage Projects |
A Double-Blind Randomized Placebo-Controlled Investigation of Autologous Muscle Derived Progenitor Cells for the Treatment of Dysphagia |
$11,015,936 |
| BioEclipse Therapeutics INC. |
Dr. Pamela Reilly Contag |
Clinical Trial Stage Projects |
PHASE 1, OPEN LABEL, DOSE-ESCALATION STUDY OF CRX100 IN PATIENTS WITH ADVANCED SOLID TUMORS |
$7,999,689 |
| Stanford University |
Dr. Joseph C. Wu |
Clinical Trial Stage Projects |
A Phase I, Pilot Study of Human Embryonic Stem Cell-Derived Cardiomyocytes in PaTients with ChrOnic Ischemic Left VentRicular Dysfunction (HECTOR) |
$6,987,507 |
| Stanford University |
Crystal Mackall |
Clinical Trial Stage Projects |
Phase 1 Clinical Trial of Autologous GD2 Chimeric Antigen Receptor T Cells for Diffuse Intrinsic Pontine Gliomas and Spinal Diffuse Midline Glioma |
$11,998,310 |
| Stanford University |
Dr. Matthew H Porteus |
Clinical Trial Stage Projects |
Phase 1/1b study of T-allo10 infusion after HLA-partially matched abdepleted-HSCT in children and young adults with hematologic malignancies. |
$10,563,822 |
| Stanford University |
Dr. Gary Steinberg |
Clinical Trial Stage Projects |
Safety and Tolerability Study of Neural Stem Cells (NR1) in Subjects with Chronic Ischemic Subcortical Stroke |
$11,998,988 |
| Cedars-Sinai Medical Center |
Clive Svendsen |
Clinical Trial Stage Projects |
CNS10-NPC-GDNF delivered into the motor cortex for the treatment of ALS |
$11,990,372 |
| City of Hope, Beckman Research Institute |
Dr. Leo D Wang |
Clinical Trial Stage Projects |
Phase I Study of IL13Rα2-Targeting CAR T Cells After Lymphodepletion for Children with Refractory or Recurrent Malignant Brain Tumors |
$8,401,309 |
| Immune-Onc Therapeutics |
Joseph Paul Woodard |
Clinical Trial Stage Projects |
Phase 1 Clinical Development of IO-202, A First-in-Class Antibody Targeting LILRB4, for the Treatment of AML with Monocytic Differentiation and CMML |
$6,000,000 |
| University of California, Davis |
Dr. Diana L. Farmer |
Clinical Trial Stage Projects |
The CuRe Trial: Cellular Therapy for In Utero Myelomeningocele Repair |
$8,905,054 |
| Rocket Pharmaceuticals, Inc. |
Dr. Gayatri Rao |
Clinical Trial Stage Projects |
A Phase I Clinical Trial for a Lentiviral Gene Therapy Targeting the TCIRG1 Gene for Infantile Malignant Osteopetrosis (IMO) |
$1,010,000 |
| University of California, San Francisco |
Steven G. Deeks |
Clinical Trial Stage Projects |
Anti-HIV duoCAR-T cell therapy for HIV infection |
$8,970,732 |
| Brain Neurotherapy Bio |
Krystof S. Bankiewicz |
Clinical Trial Stage Projects |
A Phase 1b Safety Study for MRI guided delivery of AAV2-GDNF for the treatment of Parkinson’s disease |
$5,510,462 |
| University of California, Los Angeles |
Dr. Sophie X Deng |
Clinical Trial Stage Projects |
Safety and Feasibility of Cultivated Autologous Limbal Stem Cells for Limbal Stem Cell Deficiency |
$10,301,486 |
| Cedars-Sinai Medical Center |
Clive Svendsen |
Clinical Trial Stage Projects |
Clinical Study to Assess Safety and Efficacy of Subretinal Injection of Human Neural Progenitor Cells for Treatment of Retinitis Pigmentosa |
$10,444,063 |
| City of Hope, Beckman Research Institute |
Dr Saul J Priceman |
Clinical Trial Stage Projects |
A Phase I Study of Chimeric Antigen Receptor Engineered Stem/Memory T Cells for the Treatment of HER2-Positive Brain Metastases |
$9,015,149 |
| Rocket Pharmaceuticals, Inc. |
Dr. Kinnari Patel |
Clinical Trial Stage Projects |
LADICell |
$5,867,085 |
| University of California, San Diego |
Dr. Stephanie Cherqui |
Clinical Trial Stage Projects |
Phase 1/2 study for autologous human CD34+ hematopoietic stem cells ex vivo transduced with pCCL-CTNS lentiviral vector for treatment of Cystinosis. |
$11,999,944 |
| jCyte, Inc |
Henry John Klassen |
Clinical Trial Stage Projects |
A Phase 2 Study of the Safety of Repeat Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Adult Subjects with Retinitis Pigmentosa |
$5,175,000 |
| University of California, San Francisco |
Peter Stock |
Clinical Trial Stage Projects |
Pancreatic Islets and Parathyroid Gland Co-transplantation for Treatment of Diabetes in the Intra-Muscular Site: PARADIGM |
$11,083,012 |
| Jasper Therapeutics, Inc. |
Wendy Pang |
Clinical Trial Stage Projects |
A monoclonal antibody that depletes blood stem cells and enables chemotherapy free transplants |
$2,313,398 |
| Stanford University |
Dr. Judith A Shizuru |
Clinical Trial Stage Projects |
A monoclonal antibody that depletes blood stem cells and enables chemotherapy free transplants |
$1,113,487 |
| Stanford University |
Dr. Everett H. Meyer |
Clinical Trial Stage Projects |
Induction of Tolerance by Combinatorial Therapy w/ Donor Stem Cells and Expanded Recipient Treg cells in HLA-mismatched Kidney Transplant Recipients |
$11,955,585 |
| University of California, Los Angeles |
Theodore Scott Nowicki |
Clinical Trial Stage Projects |
Genetic Modification of Stem Cells and T cells to Activate the Immune System to Target Solid Tumors |
$4,230,000 |
| Angiocrine Bioscience, Inc. |
Dr. Edward Kavalerchik |
Clinical Trial Stage Projects |
AB-205-001 Phase 1b Trial and Related Activities to Support Clinical Development of AB-205 |
$6,192,579 |
| Sangamo BioSciences, Inc. |
Bettina Cockroft |
Clinical Trial Stage Projects |
A Phase 1/2 Study to Assess the Safety, Tolerability, and Efficacy of ST-400 Autologous HSPC Transplant in Transfusion-dependent β-Thalassemia |
$5,150,000 |
| City of Hope, Beckman Research Institute |
Dr. De-Fu Zeng |
Clinical Trial Stage Projects |
Treatment of sickle cell disease by induction of mixed chimerism and immune tolerance using CD4+ T-depleted haploidentical blood stem cell transplant |
$4,352,180 |
| Stanford University |
Dr. David B. Miklos |
Clinical Trial Stage Projects |
Phase 1 Study of CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Adults with Recurrent or Refractory B Cell Malignancies |
$11,034,982 |
