Human Stem Cell Use: Directly Reprogrammed Cell

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Generation of human airway stem cells by direct transcriptional reprogramming for disease modeling and regeneration

Research Objective We will generate human airway stem cells by direct transcriptional reprogramming of fibroblasts. We will use these induced airway stem cells to model motile cilia disease in a dish. Impact Generating airway stem cells through reprogramming will create a scalable and editable cell line from which we can derive airway epithelium, thus enabling […]