Bioengineering technology for fast optical control of differentiation and function in stem cells and stem cell progeny

  • Post author:
  • Post category:

Embryonic stem (ES) cells potentially could provide clinically important replacement tissue for central nervous system (CNS) disease treatment, and regenerative medicine approaches involving ES cells have been suggested for common…

Continue ReadingBioengineering technology for fast optical control of differentiation and function in stem cells and stem cell progeny

Addressing the Cell Purity and Identity Bottleneck Through Generation and Expansion of Clonal Human Embryonic Progenitor Cell Lines

  • Post author:
  • Post category:

Human embryonic stem (hES) cells and induced pluripotent (iPS) cells, such as reprogrammed skin cells, offer the potential to revolutionize medicine because they can replicate indefinitely and become virtually any…

Continue ReadingAddressing the Cell Purity and Identity Bottleneck Through Generation and Expansion of Clonal Human Embryonic Progenitor Cell Lines

In Utero Model to Assess the Fate of Transplanted Human Cells for Translational Research and Pediatric Therapies

  • Post author:
  • Post category:

nfants with inherited blood diseases (such as sickle cell anemia, thalassemia, bleeding disorders) or other inherited metabolic disorders can be identified early in development using sophisticated diagnostic tests. Currently, the…

Continue ReadingIn Utero Model to Assess the Fate of Transplanted Human Cells for Translational Research and Pediatric Therapies

Maximizing the Safety of Induced Pluripotent Stem Cells as an Infusion Therapy: Limiting the Mutagenic Threat of Retroelement Retrotransposition during iPSC Generation, Expansion and Differentiation

  • Post author:
  • Post category:

The ability to convert human skin cells to induced pluripotent stem cells (IPSCs) represents a seminal break-through in stem cell biology. This advance effectively circumvents the problem of immune rejection…

Continue ReadingMaximizing the Safety of Induced Pluripotent Stem Cells as an Infusion Therapy: Limiting the Mutagenic Threat of Retroelement Retrotransposition during iPSC Generation, Expansion and Differentiation