The Bridges to Stem Cell Research Internship Program (BSCRIP) has continued to build upon the past success of our Internship Program by including new coursework for interns, establishing patient engagement and community outreach, and requiring regulatory affairs training. Our expanded Program has accelerated the training and expansion of the pool of personnel
with the expertise necessary to undertake careers in regenerative medicine. Last year, ten highly competitive trainees were recruited from the university’s diverse student
populations, including individuals from diverse and under-represented backgrounds that might not otherwise have hadthe chance to attain the essential expertise to contribute to the ultimate goal of delivering stem-cell
based therapies to patients. A newly optimized curriculum for Trainees at the home institution included a regulatory affairs course providing information about
healthcare product regulation and development, colloquia and community outreach activities designed to provide students with educational and patient engagement
opportunities, and participation in a biomedical ethics course. Trainees completed a comprehensive, externally-provided laboratory training course which includes
hands-on maintenance and characterization of human embryonic and induced pluripotent stem cells within a state-of-the-art Training Center designed by noted experts
in the field. Trainees completed a 12-month internship experience at one of four partnering stem cell research facilities located nearby, or at local biotechnology
companies specializing in human stem cell research and development. During the internship period, Trainees attended research seminars, met and presented their
scientific progress at monthly colloquia with other trainees and participating host mentors and scientists, and present scientific posters encompassing their data at local
and regional scientific meetings - including ISSCR. The culmination of the training program was completed following submission of a written thesis and oral thesis defense for graduate-level trainees, a final Poster
Presentation Symposium, and participation at the highly successful Annual CIRM Bridges Meeting located this year at Coronado, California. The training program enabled students of diverse background to contribute their
knowledge and technical skills developed upon completion of the training period to the great promise of stem cell-based treatment therapies for patients.
Reporting Period:
Year 2
The Bridges to Stem Cell Research Internship Program (BSCRIP) has continued to build upon the past success of our Internship Program by including new or continuing coursework for interns, establishing new patient engagement and community outreach events, and requiring regulatory affairs training. Our expanded Program has accelerated the training and expansion of the pool of personnel with the expertise necessary to undertake careers in regenerative medicine. Last year, ten highly competitive trainees were once again recruited from the university’s diverse student populations, including individuals from under-represented backgrounds that might not otherwise have had the chance to attain the essential expertise to contribute to the ultimate goal of delivering stem-cell based therapies to patients. A continuation of an optimized curriculum for Trainees at the home institution included a regulatory affairs course providing information about healthcare product regulation and development, colloquia and community outreach activities designed to provide students with educational and patient engagement opportunities, and participation in a biomedical ethics course. Trainees completed a comprehensive, externally-provided laboratory training course which includes hands-on maintenance and characterization of human embryonic and induced pluripotent stem cells within a state-of-the-art Training Center designed by noted experts in the field. Trainees completed a 12-month internship experience at one of four partnering stem cell research facilities located nearby, or at local biotechnology companies specializing in human stem cell research and development. During the internship period, Trainees attended research seminars, met and presented their scientific progress at monthly colloquia with other trainees and participating host mentors and scientists, and present scientific posters encompassing their data at local, regional or international scientific meetings - including ISSCR. The culmination of the training program was completed following submission of a written thesis and oral thesis defense for graduate-level trainees, a final Poster Presentation Symposium, and participation at the highly successful Annual CIRM Bridges Meeting located this year at Coronado, California. The training program enabled students of diverse background to contribute their knowledge and technical skills developed upon completion of the training period to the great promise of stem cell-based treatment therapies for patients.
Reporting Period:
Year 3
The Bridges to Stem Cell Research Internship Program (BSCRIP) has continued to build upon the past success of our Internship Program by including new or continuing coursework for interns, establishing new patient engagement and community outreach events, and requiring regulatory affairs training. Our expanded Program has accelerated the training and expansion of the pool of personnel with the expertise necessary to undertake careers in regenerative medicine. Last year, ten highly competitive trainees were once again recruited from the university’s diverse student populations, including individuals from under-represented backgrounds that might not otherwise have had the chance to attain the essential expertise to contribute to the ultimate goal of delivering stem-cell based therapies to patients. A continuation of an optimized curriculum for Trainees at the home institution included a regulatory affairs course providing information about healthcare product regulation and development, colloquia and community outreach activities designed to provide students with educational and patient engagement opportunities, and participation in a biomedical ethics course. All interns participated in the extensive and year-round “Americans for Cures Program for the Bridges Internship, a yearly patient engagement program and a new addition this year. Trainees completed a comprehensive, externally-provided laboratory training course which includes hands-on maintenance and characterization of human embryonic and induced pluripotent stem cells within a state-of-the-art Training Center designed by noted experts in the field. Trainees completed a 12-month internship experience at one of four partnering stem cell research facilities located nearby, or at local biotechnology companies specializing in human stem cell research and development. During the internship period, Trainees attended research seminars, met and presented their scientific progress at monthly colloquia with other trainees and participating host mentors and scientists, and present scientific posters encompassing their data at local, regional or international scientific meetings - including ISSCR. The culmination of the training program was completed following submission of a written thesis and oral thesis defense for graduate-level trainees, a final Poster Presentation Symposium, and participation at the highly successful Annual CIRM Bridges Meeting located this year at San Francisco, California. The training program enabled students of diverse background to contribute their knowledge and technical skills developed upon completion of the training period to the great promise of stem cell-based treatment therapies for patients.
Reporting Period:
Year 4
The Bridges to Stem Cell Research Internship Program (BSCRIP) has continued to build upon the past success of our Internship Program by including new or continuing coursework for interns, establishing new patient engagement and community outreach events, and requiring regulatory affairs training. Our expanded Program has accelerated the training and expansion of the pool of personnel with the expertise necessary to undertake careers in regenerative medicine. The ongoing COVID-19 pandemic has necessitated some changes to our Program, including the use of Zoom software for many events and meetings. Last year, ten highly competitive trainees were once again recruited from the university’s diverse student populations, including individuals from under-represented backgrounds that might not otherwise have had the chance to attain the essential expertise to contribute to the ultimate goal of delivering stem-cell based therapies to patients. A continuation of an optimized curriculum for Trainees at the home institution included a regulatory affairs course providing information about healthcare product regulation and development, colloquia and community outreach activities designed to provide students with educational and patient engagement opportunities, and participation in a biomedical ethics course. All interns participated in personalized patient engagement program, and trainees completed a comprehensive, externally-provided laboratory training course designed by PluriCORE and Dr. Victoria Fox which includes hands-on maintenance and characterization of human embryonic and induced pluripotent stem cells within a state-of-the-art Training Center designed by noted experts in the field. Trainees completed a 12-month internship experience at one of four partnering stem cell research facilities located nearby, or at local biotechnology companies specializing in human stem cell research and development. During the internship period, Trainees attended research seminars, met and presented their scientific progress at monthly colloquia with other trainees and participating host mentors and scientists, and present scientific posters encompassing their data at local, regional or international scientific meetings - including ISSCR. The culmination of the training program was completed following submission of a written thesis and oral thesis defense for graduate-level trainees, a final Poster Presentation Symposium, and participation at the highly successful Annual CIRM Bridges Meeting located this year via Zoom. The training program enabled students of diverse background to contribute their knowledge and technical skills developed upon completion of the training period to the great promise of stem cell-based treatment therapies for patients.
Reporting Period:
Year 5 – Supplemental
The Bridges to Stem Cell Research Internship Program (BSCRIP) has continued to build upon the past success of our Internship Program by including new or continuing coursework for interns, establishing new patient engagement and community outreach events, devising a diversity, equity, and inclusion plan, and requiring regulatory affairs training. Our expanded Program has accelerated the training and expansion of the pool of personnel with the expertise necessary to undertake careers in regenerative medicine. The ongoing COVID-19 pandemic has necessitated some changes to our Program, including the use of Zoom software for many events and meetings. Last year, ten highly competitive trainees were once again recruited from the university’s diverse student populations, including individuals from under-represented backgrounds that might not otherwise have had the chance to attain the essential expertise to contribute to the ultimate goal of delivering stem-cell based therapies to patients. A continuation of an optimized curriculum for Trainees at the home institution included a regulatory affairs course providing information about healthcare product regulation and development, colloquia and community outreach activities designed to provide students with educational and patient engagement opportunities, and participation in a biomedical ethics course. All interns participated in a personalized patient engagement program, and trainees completed a comprehensive, externally-provided laboratory training course designed by Open Biopharma Research and Training Institute and Richard Jaenisch, MPH which includes hands-on maintenance and characterization of tissue culture and stem cells within a state-of-the-art Training Center designed by noted experts in the field. Trainees completed a 12-month internship experience at one of four partnering stem cell research facilities located nearby, or at local biotechnology companies specializing in human stem cell research and development. During the internship period, Trainees attended research seminars, met and presented their scientific progress at colloquia with other trainees and participating host mentors and scientists, and present scientific posters encompassing their data at local, regional or international scientific meetings - including ISSCR. The culmination of the training program was completed following submission of a written thesis and oral thesis defense for graduate-level trainees, a final Poster Presentation Symposium, and participation at the highly successful Annual CIRM Bridges Meeting located this year via Zoom. The training program enabled students of diverse background to contribute their knowledge and technical skills developed upon completion of the training period to the great promise of stem cell-based treatment therapies for patients.
Grant Application Details
Application Title:
Bridges to Stem Cell Research Internship Program
Public Abstract:
The Bridges to Stem Cell Research Internship Program will build upon the past success of our Internship Program which has significantly expanded the pool of personnel with the expertise necessary to undertake careers in regenerative medicine. Highly competitive trainees will be recruited from the university’s diverse student populations which include individuals that might not otherwise have the chance to attain the essential expertise to contribute to the ultimate goal of delivering stem-cell based therapies to patients. A newly optimized curriculum for Trainees at the home institution includes a regulatory affairs course providing information about healthcare product regulation and development, colloquia and community outreach activities designed to provide students with educational and patient engagement opportunities, and participation in a biomedical ethics course. Trainees will complete a comprehensive, externally-provided laboratory training course which includes hands-on maintenance and characterization of human embryonic and induced pluripotent stem cells within a state-of-the-art Training Center designed by noted experts in the field. Trainees will complete a 12-month internship experience at one of four partnering stem cell research facilities located nearby, or at local biotechnology companies specializing in human stem cell research and development. During the internship period, Trainees will attend research seminars, meet and present their scientific progress at monthly colloquia with other trainees and participating host mentors and scientists, and present scientific posters encompassing their data at local and regional scientific meetings. The culmination of the training program will include a written thesis and oral thesis defense for graduate-level trainees, a final Poster Presentation Symposium, and participation at the Annual CIRM Bridges Meeting. The training program will enable students of diverse background to contribute their knowledge and technical skills developed upon completion of the training period to the great promise of stem cell-based treatment therapies for patients.
Statement of Benefit to California:
Stem cell-based treatment strategies represent the future of medicine for patients with unmet medical needs. Continued progress in the development and administration of these new therapies not only require ongoing basic and translational research, but also a sustainable approach whereby the next generation of scientists and technicians build upon the initial success of previous scientific accomplishments. The proposed training program will contribute to the generation of knowledgeable and well-trained scientists and technicians by providing hands-on research experiences in combination with rigorous academic curricula. The internship has been carefully crafted to increase the number of young investigators and technicians with diverse career goals by recruiting students representing California’s diverse population who can contribute to the development of stem cell based therapies and accelerate their eventual delivery to patients benefiting by these powerful new approaches.