CIRM Stem Cell Biology Training Grant

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Publications

• Wound Repair Regen (2009): Accelerated closure of skin wounds in mice deficient in the homeobox gene Msx2. (PubMed: 19769717)
• Int J Dev Biol (2009): Analyses of regenerative wave patterns in adult hair follicle populations reveal macro-environmental regulation of stem cell activity. (PubMed: 19378257)
• Expert Opin Pharmacother (2009): Bendamustine therapy in chronic lymphocytic leukemia. (PubMed: 19527193)
• Mol Cell (2008): A biochemically defined system for coding joint formation in V(D)J recombination. (PubMed: 18722175)
• Cancer Res (2008): BMI-1 promotes ewing sarcoma tumorigenicity independent of CDKN2A repression. (PubMed: 18701473)
• Oncogene (2010): BMI-1 suppresses contact inhibition and stabilizes YAP in Ewing sarcoma. (PubMed: 21170084)
• Cancer Res (2010): Cancer-associated fibroblasts enhance the gland-forming capability of prostate cancer stem cells. (PubMed: 20807814)
• Horm Cancer (2010): Cancer stem cells and microenvironment in prostate cancer progression. (PubMed: 21761361)
• Oncogene (2015): CBP/catenin antagonist safely eliminates drug-resistant leukemia-initiating cells. (PubMed: 26657156)
• J Biol Chem (2009): Cdc37 regulates Ryk signaling by stabilizing the cleaved Ryk intracellular domain. (PubMed: 19269974)
• Dev Cell (2008): Cleavage of the Wnt receptor Ryk regulates neuronal differentiation during cortical neurogenesis. (PubMed: 19000841)
• Stem Cells (2010): Comparison of reprogramming efficiency between transduction of reprogramming factors, cell-cell fusion, and cytoplast fusion. (PubMed: 20572011)
• J Invest Dermatol (2008): Complex hair cycle domain patterns and regenerative hair waves in living rodents. (PubMed: 18094733)
• Endocr Relat Cancer (2013): Contextual effect of repression of bone morphogenetic protein activity in prostate cancer. (PubMed: 24042462)
• Am J Respir Crit Care Med (2009): Deletion of Pten expands lung epithelial progenitor pools and confers resistance to airway injury. (PubMed: 19574443)
• J Cell Physiol (2014): Dependence of Castration-Resistant Prostate Cancer (CRPC) Stem Cells on CRPC-Associated Fibroblasts. (PubMed: 24752784)
• Endocr Relat Cancer (2011): Embryonic epithelial Pten deletion through Nkx2.1-cre leads to thyroid tumorigenesis in a strain dependent manner. (PubMed: 22167068)
• PLoS One (2011): The endoplasmic reticulum chaperone protein GRP94 is required for maintaining hematopoietic stem cell interactions with the adult bone marrow niche. (PubMed: 21647226)
• Development (2009): EphA4 as an effector of Twist1 in the guidance of osteogenic precursor cells during calvarial bone growth and in craniosynostosis. (PubMed: 19201948)
• Dev Cell (2018): Essential Role of Nr2f Nuclear Receptors in Patterning the Vertebrate Upper Jaw. (PubMed: 29358039)
• PLoS Genet (2012): An Essential Role of Variant Histone H3.3 for Ectomesenchyme Potential of the Cranial Neural Crest. (PubMed: 23028350)
• Nucleic Acids Res (2007): Extent to which hairpin opening by the Artemis:DNA-PKcs complex can contribute to junctional diversity in V(D)J recombination. (PubMed: 17932067)
• J Invest Dermatol (2015): Feather on the Cap of Medicine. (PubMed: 26066892)
• Pediatr Res (2009): Fibroblast growth factor 10 plays a causative role in the tracheal cartilage defects in a mouse model of Apert syndrome. (PubMed: 19581825)
• Development (2013): Foxc1 controls the growth of the murine frontal bone rudiment by direct regulation of a Bmp response threshold of Msx2. (PubMed: 23344708)
• PLoS One (2013): Functional impacts of NRXN1 knockdown on neurodevelopment in stem cell models. (PubMed: 23536886)
• Curr Cancer Drug Targets (2011): The gamma catenin/CBP complex maintains survivin transcription in beta-catenin deficient/depleted cancer cells. (PubMed: 21158719)
• Stem Cell Res Ther (2012): The gene expression profiles of induced pluripotent stem cells from individuals with childhood cerebral adrenoleukodystrophy are consistent with proposed mechanisms of pathogenesis. (PubMed: 23036268)
• Cell (2008): Germline competent embryonic stem cells derived from rat blastocysts. (PubMed: 19109898)
• Stem Cells (2008): Human amniotic fluid stem cells can integrate and differentiate into epithelial lung lineages. (PubMed: 18719226)
• Proc Natl Acad Sci U S A (2009): Identification and characterization of posttranslational modification-specific binding proteins in vivo by mammalian tethered catalysis. (PubMed: 19706462)
• Virology (2009): Identification of a novel common proviral integration site, flit-1, in feline leukemia virus induced thymic lymphoma. (PubMed: 19203775)
• Dev Biol (2010): Inactivation of Msx1 and Msx2 in neural crest reveals an unexpected role in suppressing heterotopic bone formation in the head. (PubMed: 20398647)
• Stem Cell Res Ther (2015): Induced pluripotent stem cell models of Zellweger spectrum disorder show impaired peroxisome assembly and cell type-specific lipid abnormalities. (PubMed: 26319495)
• Stem Cells (2009): Klf4 interacts directly with Oct4 and Sox2 to promote reprogramming. (PubMed: 19816951)
• Cell Stem Cell (2013): Klf4 Organizes Long-Range Chromosomal Interactions with the Oct4 Locus in Reprogramming and Pluripotency. (PubMed: 23747203)
• J Biol Chem (2010): Kruppel-like factor 4 (Klf4) prevents embryonic stem (ES) cell differentiation by regulating Nanog gene expression. (PubMed: 20071344)
• J Biol Chem (2007): Length-dependent binding of human XLF to DNA and stimulation of XRCC4.DNA ligase IV activity. (PubMed: 17317666)
• PLoS One (2013): Loss of survivin in the prostate epithelium impedes carcinogenesis in a mouse model of prostate adenocarcinoma. (PubMed: 23936028)
• Curr Top Dev Biol (2010): Lung organogenesis. (PubMed: 20691848)
• Dev Biol (2008): Mechanisms of TGFbeta inhibition of LUNG endodermal morphogenesis: the role of TbetaRII, Smads, Nkx2.1 and Pten. (PubMed: 18602626)
• J Clin Invest (2012): Mesodermal Pten inactivation leads to alveolar capillary dysplasia-like phenotype. (PubMed: 23023706)
• Elife (2017): A minimally sufficient model for rib proximal-distal patterning based on genetic analysis and agent-based simulations. (PubMed: 29068314)
• PLoS One (2011): Modeling initiation of ewing sarcoma in human neural crest cells. (PubMed: 21559395)
• Cancer Res (2007): Mouse models of prostate adenocarcinoma with the capacity to monitor spontaneous carcinogenesis by bioluminescence or fluorescence. (PubMed: 17671224)
• Dev Biol (2016): Msx1 and Msx2 function together in the regulation of primordial germ cell migration in the mouse. (PubMed: 27435625)
• Dev Biol (2007): Msx1 and Msx2 regulate survival of secondary heart field precursors and post-migratory proliferation of cardiac neural crest in the outflow tract. (PubMed: 17601530)
• Dev Dyn (2008): NF-kB induces lung maturation during mouse lung morphogenesis. (PubMed: 18161062)
• PLoS One (2012): A novel dual-color reporter for identifying insulin-producing beta-cells and classifying heterogeneity of insulinoma cell lines. (PubMed: 22530041)
• J Hematol Oncol (2009): The occurrence and management of fluid retention associated with TKI therapy in CML, with a focus on dasatinib. (PubMed: 19909541)
• J Clin Invest (2011): Parabronchial smooth muscle constitutes an airway epithelial stem cell niche in the mouse lung after injury. (PubMed: 21985786)
• J Biol Chem (2011): Polynucleotide kinase and aprataxin-like forkhead-associated protein (PALF) acts as both a single-stranded DNA endonuclease and a single-stranded DNA 3′ exonuclease and can participate in DNA end joining in a biochemical system. (PubMed: 21885877)
• Blood (2009): Prox1 physically and functionally interacts with COUP-TFII to specify lymphatic endothelial cell fate. (PubMed: 18815287)
• J Urol (2009): PTEN knockout prostate cancer as a model for experimental immunotherapy. (PubMed: 19010487)
• Proc Natl Acad Sci U S A (2008): Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium. (PubMed: 19033462)
• Mol Ther (2010): Regulated expansion of human pancreatic beta-cells. (PubMed: 20389286)
• Science (2011): Self-organizing and stochastic behaviors during the regeneration of hair stem cells. (PubMed: 21527712)
• Development (2010): Signaling via Alk5 controls the ontogeny of lung Clara cells. (PubMed: 20147383)
• Cell Res (2011): Smek promotes histone deacetylation to suppress transcription of Wnt target gene brachyury in pluripotent embryonic stem cells. (PubMed: 21423269)
• Dev Biol (2009): Stabilized beta-catenin in lung epithelial cells changes cell fate and leads to tracheal and bronchial polyposis. (PubMed: 19631635)
• Biol Open (2014): Stat3 signaling regulates embryonic stem cell fate in a dose-dependent manner. (PubMed: 25238758)
• PLoS One (2010): Targeted mutation of the mouse Grp94 gene disrupts development and perturbs endoplasmic reticulum stress signaling. (PubMed: 20520781)
• J Biol Chem (2015): Unifying the DNA end-processing roles of the artemis nuclease: Ku-dependent artemis resection at blunt DNA ends. (PubMed: 26276388)
• Oncogene (2017): Wnt/beta-catenin activation and macrophage induction during liver cancer development following steatosis. (PubMed: 28671671)