Multiomic Studies of Idiopathic Intellectual Disability and Autism Spectrum Disorder (ID/ASD)
Grant Award Details
Grant Type:
Grant Number:
DISC4-16292
Investigator(s):
Award Value:
$17,365,387
Status:
Pre-Active
Grant Application Details
Application Title:
Multiomic Studies of Idiopathic Intellectual Disability and Autism Spectrum Disorder (ID/ASD)
Public Abstract:
Research Objective
We provide mechanistic insight into idiopathic Intellectual Disability (ID) and Autism Spectrum Disorder (ASD) based on aberrant redox-mediated posttranslational modifications related to air pollution
Impact
How air pollution contributes to ASD/ID should provide impetus for environmental control of such pollution. With our insights into idiopathic ID and ASD, new treatment approaches will become possible.
We provide mechanistic insight into idiopathic Intellectual Disability (ID) and Autism Spectrum Disorder (ASD) based on aberrant redox-mediated posttranslational modifications related to air pollution
Impact
How air pollution contributes to ASD/ID should provide impetus for environmental control of such pollution. With our insights into idiopathic ID and ASD, new treatment approaches will become possible.
Statement of Benefit to California:
By discovering the mechanisms whereby air pollution and other environmental factors contribute to the development of idiopathic ID/ASD, this study will help develop new ways to prevent and treat this important cause of ID/ASD.