| Shared Labs Grant – Enhancing/Expanding SRLs | Dr. Bruce R. Conklin | A Center for Stem Cell Disease Modeling and Therapeutics |
$4,000,000 |
| Foundation – Discovery Stage Research Projects | Dr. Steve M. Finkbeiner | Lewy body dementia, 𝛼-synuclein, and cell-specific mechanisms of neurodegeneration |
$1,739,760 |
| Foundation – Discovery Stage Research Projects | Julia Kaye | Developing a Human Model of Sporadic ALS Using Machine Learning and Robotic Microscopy |
$1,406,622 |
| Research Training Grant | Dr. Bruce R. Conklin | CIRM Regenerative Medicine Research Training Program |
$5,373,742 |
| Quest – Discovery Stage Research Projects | Lyandysha (Lana) Viktorovna Zholudeva | Excitatory spinal interneurons from human pluripotent stem cells to treat spinal cord injury |
$2,942,198 |
| Quest – Discovery Stage Research Projects | Dr. Deepak Srivastava | Modified RNA-Based Gene Therapy for Cardiac Regeneration Through Cardiomyocyte Proliferation |
$1,565,784 |
| Quest – Discovery Stage Research Projects | Li Gan | Develop iPSC-derived microglia to treat progranulin-deficient Frontotemporal Dementia |
$1,547,157 |
| Quest – Discovery Stage Research Projects | Dr. Deepak Srivastava | Direct Cardiac Reprogramming for Regenerative Medicine |
$2,392,157 |
| Quest – Discovery Stage Research Projects | Dr. Deepak Srivastava | Use of Human iPSC-derived Endothelial Cells for Calcific Aortic Valve Disease Therapeutics |
$2,400,048 |
| Therapeutic Translational Research Projects | Dr. Yadong Huang | Human iPSC-derived GABAergic Progenitors for Alzheimer’s Disease Treatment |
$1,900,000 |
| Conference | Dr. Deepak Srivastava | ISSCR – Roddenberry International Symposium on Cellular reprogramming |
$43,000 |
| Conference | Dr. Steve M. Finkbeiner | THE 5TH ANNUAL CALIFORNIA ALS PAC10 AND RESEARCH NETWORK MEETING |
$9,529 |
| Conference | Dr. Deepak Srivastava | Keystone Symposia, “Stem Cells and Reprogramming” |
$50,000 |
| Disease Team Planning | Dr. Deepak Srivastava | Pluripotent Stem Cell–Based Therapy for Heart Disease |
$13,505 |
| Basic Biology V | Sheng Ding PhD | A novel druggable mechanism to safeguard stem cell genome |
$1,294,495 |
| Early Translational IV | Dr. Steve M. Finkbeiner | Development of Novel Autophagy Inducers to Block the Progression of and Treat Amyotrophic Lateral Sclerosis (ALS) and Other Neurodegenerative Diseases |
$2,049,053 |
| Creativity Awards | Ms. Shannon Noonan | Gladstone Summer Scholars (GSS) internship program |
$35,044 |
| Basic Biology IV | Dr. Benoit Bruneau | Epigenetic regulation of human cardiac differentiation |
$1,568,148 |
| Basic Biology IV | Dr. Steve M. Finkbeiner | Common molecular mechanisms in neurodegenerative diseases using patient based iPSC neurons |
$1,395,184 |
| Basic Biology IV | Sheng Ding PhD | A new paradigm of lineage-specific reprogramming |
$1,568,395 |
| Early Translational III | Dr. Deepak Srivastava | Direct Cardiac Reprogramming for Heart Regeneration |
$5,795,871 |
| Training Grant I-2 | Dr. Robert W Mahley | Gladstone CIRM Scholar Program |
$2,192,073 |
| Research Training II | Dr. Robert W Mahley | Gladstone CIRM Scholars Program |
$4,869,300 |
| Basic Biology III | Dr. Deepak Srivastava | Mechanisms of Direct Cardiac Reprogramming |
$1,572,380 |
| Research Leadership | Dr. Todd C. McDevitt | Engineering microscale tissue constructs from human pluripotent stem cells |
$5,849,100 |
| Research Leadership | Dr. Kevin Kit Parker PhD | Engineering Cardiac Tissue for Regeneration and Drug Development |
$0 |
| New Faculty I | Sheng Ding PhD | Reprogramming of human somatic cells back to pluripotent embryonic stem cells |
$1,320,101 |
| Early Translational I | Dr. Warner C Greene | Maximizing the Safety of Induced Pluripotent Stem Cells as an Infusion Therapy: Limiting the Mutagenic Threat of Retroelement Retrotransposition during iPSC Generation, Expansion and Differentiation |
$1,280,001 |
| Shared Labs | Dr. Deepak Srivastava | The Gladstone CIRM Shared Human Embryonic Stem Cell Core Laboratory |
$842,672 |
| Shared Labs | Dr. Deepak Srivastava | The Gladstone CIRM Shared Human Embryonic Stem Cell Core Laboratory |
$1,698,515 |
| New Faculty II | Dr. Yadong Huang | Defining the Isoform-Specific Effects of Apolipoprotein E on the Development of iPS Cells into Functional Neurons in Vitro and in Vivo |
$2,757,303 |
| New Faculty II | Dr. Benoit Bruneau | Induction of cardiogenesis in pluripotent cells via chromatin remodeling factors |
$2,723,653 |
| New Cell Lines | Sheng Ding PhD | Derivation of New ICM-stage hESCs |
$778,859 |
| New Cell Lines | Dr. Bruce R. Conklin | Induced Pluripotent Stem Cells for Cardiovascular Diagnostics |
$1,708,560 |
| New Cell Lines | Robert V Farese | Establishment of Frontotemporal Dementia Patient-Specific Induced Pluripotent Stem (iPS) Cell Lines with Defined Genetic Mutations |
$1,696,424 |
| Comprehensive Grant | Dr. Deepak Srivastava | microRNA Regulation of Cardiomyocyte Differentiation from Human Embryonic Stem Cells |
$2,994,719 |
| SEED Grant | Dr. Warner C Greene | The APOBEC3 Gene Family as Guardians of Genome Stability in Human Embryonic Stem Cells |
$717,363 |
| SEED Grant | Dr. Fen-Biao N. Gao | MicroRNAs in Human Stem Cell Differentiation and Mental Disorders |
$748,800 |
| SEED Grant | Dr. Eric Verdin | Role of HDAC in human stem cells pluripotentiality and differentiation |
$590,997 |
