If the therapeutic potential of human embryonic stem (ES) cells is to be realized, the ability to produce pluripotent stem cells with defined genetic backgrounds is essential. Pluripotent cells, through…
Little is known about human Neurla Crest (NC) cells, a transient population of cells briefly present during very early human development; the reason why these cells are extremely difficult to…
Embryonic stem cell-based therapies hold great promise for the treatment of many human diseases. These therapeutic strategies involve the culture and manipulation of embryonic stem cells grown outside the human…
Stroke is the third leading cause of death and the leading cause of disability in this country, affecting about 650,000 people in the US each year. Currently approved therapies for…
Human embryonic stem cells can be changed into virtually any cell type in the adult body. Because of this unique capability, these cells have the potential to cure a vast…
Stem cells are multipotent, meaning that they can develop into any cell type of the human body. Biomedical applications propose that, after introduction into humans, stem cells could replenish damaged…
Embryonic Stem (ES) cells can be grown indefinitely in the lab and can be turned into any cell type of the human body. Because of these properties, it may one…
The constant exposure of cells to endogenous and exogenous agents that inflict DNA damage requires active repair processes to eliminate potentially mutagenic events in stem cells leading to cancer. The…
Non-invasive imaging techniques for an in vivo tracking of transplanted stem cells offer real-time insight into the underlying biological processes of new stem cell based therapies, with the aim to…
Our understanding of the effect of immunosuppressive agents on stem cell proliferation and differentiation in the central nervous system is limited. Indeed, even the necessity for long-term immunosuppression to promote…
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