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Human endothelial reprogramming for hematopoietic stem cell therapy.

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  • Post published:March 2, 2026
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The current roadblocks to hematopoietic stem cell (HSC) therapies include the rarity of matched donors for bone marrow transplant, engraftment failures, common shortages of donated blood, and the inability to…

Continue ReadingHuman endothelial reprogramming for hematopoietic stem cell therapy.

Modeling disease in human embryonic stem cells using new genetic tools

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  • Post published:March 2, 2026
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The use of stem cells or stem cell-derived cells to treat disease is one important goal of stem cell research. A second, important use for stem cells is the creation…

Continue ReadingModeling disease in human embryonic stem cells using new genetic tools

The HD iPSC Consortium: Repeat Length Dependent Phenotypes for Assay Development

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  • Post published:March 2, 2026
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Continue ReadingThe HD iPSC Consortium: Repeat Length Dependent Phenotypes for Assay Development

Elucidating Molecular Basis of Hypertrophic Cardiomyopathy with Human Induced Pluripotent Stem Cells

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  • Post published:March 2, 2026
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Familial hypertrophic cardiomyopathy (HCM) is the leading cause of sudden cardiac death in young people, including trained athletes, and is the most common inherited heart defect. Until now, studies in…

Continue ReadingElucidating Molecular Basis of Hypertrophic Cardiomyopathy with Human Induced Pluripotent Stem Cells

Homologous recombination in human pluripotent stem cells using adeno-associated virus.

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  • Post published:March 2, 2026
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Since their discovery in 1998, human embryonic stem cells (hESCs) have been considered to hold great potential for the treatment of many currently incurable diseases. Possibly the most exciting application…

Continue ReadingHomologous recombination in human pluripotent stem cells using adeno-associated virus.

Cellular tools to study brain diseases affecting synaptic transmission

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  • Post published:March 2, 2026
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There is a group of brain diseases that are caused by functional abnormalities. The brains of patients afflicted with these diseases which include autism spectrum disorders, schizophrenia, depression, and mania…

Continue ReadingCellular tools to study brain diseases affecting synaptic transmission

Antibody tools to deplete or isolate teratogenic, cardiac, and blood stem cells from hESCs

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  • Post published:March 2, 2026
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Purity is as important for cell-based therapies as it is for treatments based on small-molecule drugs or biologics. Pluripotent stem cells possess two properties: they are capable of self regeneration…

Continue ReadingAntibody tools to deplete or isolate teratogenic, cardiac, and blood stem cells from hESCs

Tri-resolution Visualization System for Stem Cells and Tissue Regeneration Monitoring

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  • Post published:March 2, 2026
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The 3D imaging techniques of CT and MRI have virtually eliminated the need for exploratory surgery – a procedure which was common in difficult cases just 20-30 years ago. Not…

Continue ReadingTri-resolution Visualization System for Stem Cells and Tissue Regeneration Monitoring

Use of iPS cells (iPSCs) to develop novels tools for the treatment of spinal muscular atrophy.

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  • Post published:March 2, 2026
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Spinal Muscular Atrophy (SMA) is one of the most common lethal genetic diseases in children. One in thirty five people carry a mutation in a gene called survival of motor…

Continue ReadingUse of iPS cells (iPSCs) to develop novels tools for the treatment of spinal muscular atrophy.

Engineering Defined and Scaleable Systems for Dopaminergic Neuron Differentiation of hPSCs

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  • Post published:March 2, 2026
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Human pluripotent stem cells (hPSC) have the capacity to differentiate into every cell in the adult body, and they are thus a highly promising source of differentiated cells for the…

Continue ReadingEngineering Defined and Scaleable Systems for Dopaminergic Neuron Differentiation of hPSCs
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