| [(18)F]FDG-PET and [(18)F]MPPF-PET are brain biomarkers for the creatine transporter Slc6a8 loss of function mutation. |
2025 |
Sci Rep |
| ADMET-AI Enables Interpretable Predictions of Drug-Induced Cardiotoxicity. |
2025 |
Circulation |
| Allogeneic CD33-directed CAR-NKT cells for the treatment of bone marrow-resident myeloid malignancies. |
2025 |
Nat Commun |
| Derivation and Characterization of Isogenic OPA1 Mutant and Control Human Pluripotent Stem Cell Lines. |
2025 |
Cells |
| Generating allogeneic CAR-NKT cells for off-the-shelf cancer immunotherapy with genetically engineered HSP cells and feeder-free differentiation culture. |
2025 |
Nat Protoc |
| A facilitatory role of astrocytes in axonal regeneration after acute and chronic spinal cord injury. |
2024 |
Exp Neurol |
| A framework for N-of-1 trials of individualized gene-targeted therapies for genetic diseases. |
2024 |
Nat Commun |
| A novel high-titer, bifunctional lentiviral vector for autologous hematopoietic stem cell gene therapy of sickle cell disease. |
2024 |
Mol Ther Methods Clin Dev |
| A Panoramic View of Cell Population Dynamics in Mammalian Aging. |
2024 |
bioRxiv |
| A therapy for suppressing canonical and noncanonical SARS-CoV-2 viral entry and an intrinsic intrapulmonary inflammatory response. |
2024 |
Proc Natl Acad Sci U S A |
| AMPK Drives both Glycolytic and Oxidative Metabolism in Murine and Human T Cells During Graft-versus-host Disease. |
2024 |
Blood Adv |
| An age-progressive platelet differentiation path from hematopoietic stem cells causes exacerbated thrombosis. |
2024 |
Cell |
| An Endothelial Cell Is Not Simply an Endothelial Cell. |
2024 |
Stem Cells Dev |
| An improved method for generating human spinal cord neural stem cells. |
2024 |
Exp Neurol |
| Antigen-Specific T Cell Receptor Discovery for Treating Progressive Multifocal Leukoencephalopathy. |
2024 |
bioRxiv |
| Antisense oligonucleotide therapy in an individual with KIF1A-associated neurological disorder. |
2024 |
Nat Med |
| Antiviral cellular therapy for enhancing T-cell reconstitution before or after hematopoietic stem cell transplantation (ACES): a two-arm, open label phase II interventional trial of pediatric patients with risk factor assessment. |
2024 |
Nat Commun |
| CAR-T cell therapy targeting surface expression of TYRP1 to treat cutaneous and rare melanoma subtypes. |
2024 |
Nat Commun |
| Comparing fabrication techniques for engineered cardiac tissue. |
2024 |
J Biomed Mater Res A |
| CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity. |
2024 |
Cell Stem Cell |
| Custom-engineered hydrogels for delivery of human iPSC-derived neurons into the injured cervical spinal cord. |
2024 |
Biomaterials |
| Defining metabolic flexibility in hair follicle stem cell induced squamous cell carcinoma. |
2024 |
Sci Adv |
| Disease modeling and pharmacological rescue of autosomal dominant retinitis pigmentosa associated with RHO copy number variation. |
2024 |
Elife |
| Early-life stress triggers long-lasting organismal resilience and longevity via tetraspanin. |
2024 |
Sci Adv |
| Engineered Protein Hydrogels as Biomimetic Cellular Scaffolds. |
2024 |
Adv Mater |
| Engineering allorejection-resistant CAR-NKT cells from hematopoietic stem cells for off-the-shelf cancer immunotherapy. |
2024 |
Mol Ther |
| Fatty acid oxidation in immune function. |
2024 |
Front Immunol |
| Frontiers in CAR-T cell therapy for autoimmune diseases. |
2024 |
Trends Pharmacol Sci |
| Functional outcome of the anterior vaginal wall in a pelvic surgery injury rat model after treatment with stem cell-derived progenitors of smooth muscle cells. |
2024 |
Stem Cell Res Ther |
| Gene editing improves endoplasmic reticulum-mitochondrial contacts and unfolded protein response in Friedreich’s ataxia iPSC-derived neurons. |
2024 |
Front Pharmacol |
| Generation of ‘semi-guided’ cortical organoids with complex neural oscillations. |
2024 |
Nat Protoc |
| Generation of allogeneic CAR-NKT cells from hematopoietic stem and progenitor cells using a clinically guided culture method. |
2024 |
Nat Biotechnol |
| Generation of antigen-specific mature T cells from RAG1(-/-)RAG2(-/-)B2M(-/-) stem cells by engineering their microenvironment. |
2024 |
Nat Biomed Eng |
| Harnessing Biomaterials to Amplify Immunity in Aged Mice through T Memory Stem Cells. |
2024 |
ACS Nano |
| Increased mitochondrial mutation heteroplasmy induces aging phenotypes in pluripotent stem cells and their differentiated progeny. |
2024 |
Aging Cell |
| Inhibition of Pyruvate Oxidation Diminishes Melanoma Progression. |
2024 |
J Invest Dermatol |
| Lentiviral vectors for precise expression to treat X-linked lymphoproliferative disease. |
2024 |
Mol Ther Methods Clin Dev |
| Locoregional delivery of IL-13Ralpha2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial. |
2024 |
Nat Med |
| Modeling Cortical Versus Hippocampal Network Dysfunction in a Human Brain Assembloid Model of Epilepsy and Intellectual Disability. |
2024 |
bioRxiv |
| Multi-lineage heart-chip models drug cardiotoxicity and enhances maturation of human stem cell-derived cardiovascular cells. |
2024 |
Lab Chip |
| Netrin1 patterns the dorsal spinal cord through modulation of Bmp signaling. |
2024 |
Cell Rep |
| Non-invasive prenatal testing of beta-hemoglobinopathies using next generation sequencing, in-silico sequence size selection, and haplotyping. |
2024 |
Croat Med J |
| Overexpression of AMPKgamma2 increases AMPK signaling to augment human T cell metabolism and function. |
2024 |
J Biol Chem |
| Recent developments in translational imaging of in vivo gene therapy outcomes. |
2024 |
Mol Ther |
| Respiratory exposure to agricultural dust extract promotes increased intestinal Tnfalpha expression, gut barrier dysfunction, and endotoxemia in mice. |
2024 |
Am J Physiol Gastrointest Liver Physiol |
| Secondary bone marrow graft loss after third-party virus-specific T cell infusion: Case report of a rare complication. |
2024 |
Nat Commun |
| Small molecule inhibition of RNA binding proteins in haematologic cancer. |
2024 |
RNA Biol |
| Stem cell-derived CAR T cells show greater persistence, trafficking, and viral control compared to ex vivo transduced CAR T cells. |
2024 |
Mol Ther |
| Targeting IGF2BP3 enhances antileukemic effects of menin-MLL inhibition in MLL-AF4 leukemia. |
2024 |
Blood Adv |
| The Benefits of Stem Cell Biology and Tissue Engineering in Low-Earth Orbit. |
2024 |
Stem Cells Dev |
