Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Fat grafting rescues radiation-induced joint contracture. 2020 Stem Cells
Foxp1 Regulates Neural Stem Cell Self-Renewal and Bias Toward Deep Layer Cortical Fates. 2020 Cell Rep
From Berlin to London: HIV-1 Reservoir Reduction Following Stem Cell Transplantation. 2020 Curr HIV/AIDS Rep
Functionally heterogeneous human satellite cells identified by single cell RNA sequencing. 2020 Elife
Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease. 2020 Nat Commun
Geriatric fragility fractures are associated with a human skeletal stem cell defect. 2020 Aging Cell
Germline development in rat revealed by visualization and deletion of Prdm14. 2020 Development
Global Consensus on the Management of Limbal Stem Cell Deficiency. 2020 Cornea
Grading TESI: Crypt and villus formation in tissue-engineered small intestine alters with stem/progenitor cell source. 2020 Am J Physiol Gastrointest Liver Physiol
Guided nuclear exploration increases CTCF target search efficiency. 2020 Nat Chem Biol
Guidelines for reporting single-cell RNA-seq experiments. 2020 Nat Biotechnol
Hair-bearing human skin generated entirely from pluripotent stem cells. 2020 Nature
Heavy metals contaminating the environment of a progressive supranuclear palsy cluster induce tau accumulation and cell death in cultured neurons. 2020 Sci Rep
Human-engineered Treg-like cells suppress FOXP3-deficient T cells but preserve adaptive immune responses in vivo. 2020 Clin Transl Immunology
Immune and Inflammatory Determinants Underlying Alzheimer’s Disease Pathology. 2020 J Neuroimmune Pharmacol
Immune-evasive human islet-like organoids ameliorate diabetes. 2020 Nature
Immunodeficient mice are better for modeling the transfusion of human blood components than wild-type mice. 2020 PLoS One
Improved Titer and Gene Transfer by Lentiviral Vectors Using Novel, Small beta-Globin Locus Control Region Elements. 2020 Mol Ther
Improvement of motor and behavioral activity in Sandhoff mice transplanted with human CD34+ cells transduced with a HexA/HexB expressing lentiviral vector. 2020 J Gene Med
In Vitro Safety “Clinical Trial” of the Cardiac Liability of Hydroxychloroquine and Azithromycin as COVID19 Polytherapy. 2020 bioRxiv
Interleukin 7 receptor is required for myeloid cell homeostasis and reconstitution by hematopoietic stem cells. 2020 Exp Hematol
Label-free enrichment of fate-biased human neural stem and progenitor cells. 2020 Biosens Bioelectron
Lentiviral gene therapy for X-linked chronic granulomatous disease. 2020 Nat Med
Limbal Stem Cell Deficiency After Glaucoma Surgery. 2020 Cornea
Long-term eradication of extranodal natural killer/T-cell lymphoma, nasal type, by induced pluripotent stem cell-derived Epstein-Barr virus-specific rejuvenated T cells in vivo. 2020 Haematologica
Long-term ex vivo expansion of mouse hematopoietic stem cells. 2020 Nat Protoc
Long-term outcomes of Descemet membrane endothelial keratoplasty in eyes with prior glaucoma surgery. 2020 Am J Ophthalmol
Loss of NARS1 impairs progenitor proliferation in cortical brain organoids and leads to microcephaly. 2020 Nat Commun
Lysosomal recycling of amino acids affects ER quality control. 2020 Sci Adv
Manufacturing considerations for producing and assessing decellularized extracellular matrix hydrogels. 2020 Methods
Mechanisms of bone development and repair. 2020 Nat Rev Mol Cell Biol
Mixed chimerism and acceptance of kidney transplants after immunosuppressive drug withdrawal. 2020 Sci Transl Med
Modeling Human Cytomegalovirus-Induced Microcephaly in Human iPSC-Derived Brain Organoids. 2020 Cell Rep Med
Molecular consequences of fetal alcohol exposure on amniotic exosomal miRNAs with functional implications for stem cell potency and differentiation. 2020 PLoS One
mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortex. 2020 Elife
Multiexon deletion alleles of ATF6 linked to achromatopsia. 2020 JCI Insight
Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly. 2020 Neuron
Neural Stem Cells Improve the Delivery of Oncolytic Chimeric Orthopoxvirus in a Metastatic Ovarian Cancer Model. 2020 Mol Ther Oncolytics
NODAL inhibition promotes differentiation of pacemaker-like cardiomyocytes from human induced pluripotent stem cells. 2020 Stem Cell Res
Northstar enables automatic classification of known and novel cell types from tumor samples. 2020 Sci Rep
Novel C1q receptor-mediated signaling controls neural stem cell behavior and neurorepair. 2020 Elife
Optimization of a syngeneic murine model of bone metastasis. 2020 J Bone Oncol
Outcomes of Limbal Stem Cell Transplant: A Meta-analysis. 2020 JAMA Ophthalmol
PAWI-2 overcomes tumor stemness and drug resistance via cell cycle arrest in integrin beta3-KRAS-dependent pancreatic cancer stem cells. 2020 Sci Rep
Pluripotent Stem Cell-Based Organoid Technologies for Developing Next-Generation Vision Restoration Therapies of Blindness. 2020 J Ocul Pharmacol Ther
Post-Transcriptional Regulation of Homeostatic, Stressed, and Malignant Stem Cells. 2020 Cell Stem Cell
Proteomic analysis of young and old mouse hematopoietic stem cells and their progenitors reveals post-transcriptional regulation in stem cells. 2020 Elife
Prrx1 Fibroblasts Represent a Pro-fibrotic Lineage in the Mouse Ventral Dermis. 2020 Cell Rep
Rapid bacterial detection and antibiotic susceptibility testing in whole blood using one-step, high throughput blood digital PCR. 2020 Lab Chip
Regulatory T cells promote remyelination in the murine experimental autoimmune encephalomyelitis model of multiple sclerosis following human neural stem cell transplant. 2020 Neurobiol Dis