ApoE-Isoform-Dependent SARS-CoV-2 Neurotropism and Cellular Response. |
2021 |
Cell Stem Cell |
Application of lung microphysiological systems to COVID-19 modeling and drug discovery: a review. |
2021 |
Biodes Manuf |
Assessing Oximetry Response to Chimeric Antigen Receptor T-cell Therapy against Glioma with (19)F MRI in a Murine Model. |
2021 |
Radiol Imaging Cancer |
ATF6 is essential for human cone photoreceptor development. |
2021 |
Proc Natl Acad Sci U S A |
Autologous Ex Vivo Lentiviral Gene Therapy for Adenosine Deaminase Deficiency. |
2021 |
N Engl J Med |
BAF155 methylation drives metastasis by hijacking super-enhancers and subverting anti-tumor immunity. |
2021 |
Nucleic Acids Res |
beta-Globin Lentiviral Vectors Have Reduced Titers due to Incomplete Vector RNA Genomes and Lowered Virion Production. |
2021 |
Stem Cell Reports |
Biomaterial-based immunoengineering to fight COVID-19 and infectious diseases. |
2021 |
Matter |
Biophysical matrix cues from the regenerating niche direct muscle stem cell fate in engineered microenvironments. |
2021 |
Biomaterials |
Bioprinting of dual ECM scaffolds encapsulating limbal stem/progenitor cells in active and quiescent statuses. |
2021 |
Biofabrication |
Bromodomain containing 9 (BRD9) regulates macrophage inflammatory responses by potentiating glucocorticoid receptor activity. |
2021 |
Proc Natl Acad Sci U S A |
CAR T cells with dual targeting of CD19 and CD22 in adult patients with recurrent or refractory B cell malignancies: a phase 1 trial. |
2021 |
Nat Med |
Characterization and Biomarker Analyses of Post-COVID-19 Complications and Neurological Manifestations. |
2021 |
Cells |
Clearing the Haze: How Does Nicotine Affect Hematopoiesis before and after Birth? |
2021 |
Cancers (Basel) |
Clinical outcomes and complications of fluid-filled scleral lens devices for the management of limbal stem cell deficiency. |
2021 |
Cont Lens Anterior Eye |
Co-grafts of Human Embryonic Stem Cell Derived Retina Organoids and Retinal Pigment Epithelium for Retinal Reconstruction in Immunodeficient Retinal Degenerate Royal College of Surgeons Rats. |
2021 |
Front Neurosci |
Combining CD47 blockade with trastuzumab eliminates HER2-positive breast cancer cells and overcomes trastuzumab tolerance. |
2021 |
Proc Natl Acad Sci U S A |
Comparative transcriptomic analysis of SARS-CoV-2 infected cell model systems reveals differential innate immune responses. |
2021 |
Sci Rep |
Conservation and divergence of vulnerability and responses to stressors between human and mouse astrocytes. |
2021 |
Nat Commun |
Cranial Suture Regeneration Mitigates Skull and Neurocognitive Defects in Craniosynostosis. |
2021 |
Cell |
Craniofacial and Long Bone Development in the Context of Distraction Osteogenesis. |
2021 |
Plast Reconstr Surg |
CRISPR Screening of CAR T Cells and Cancer Stem Cells Reveals Critical Dependencies for Cell-Based Therapies. |
2021 |
Cancer Discov |
Deciphering intratumoral heterogeneity using integrated clonal tracking and single-cell transcriptome analyses. |
2021 |
Nat Commun |
Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma. |
2021 |
J Immunother Cancer |
Deep Learning-Assisted Multiphoton Microscopy to Reduce Light Exposure and Expedite Imaging in Tissues With High and Low Light Sensitivity. |
2021 |
Transl Vis Sci Technol |
Deficiency of the sedoheptulose kinase (Shpk) does not alter the ability of hematopoietic stem cells to rescue cystinosis in the mouse model. |
2021 |
Mol Genet Metab |
Development of allogeneic HSC-engineered iNKT cells for off-the-shelf cancer immunotherapy. |
2021 |
Cell Rep Med |
Development of selective bispecific Wnt mimetics for bone loss and repair. |
2021 |
Nat Commun |
Development of Stem Cell-Derived Immune Cells for Off-the-Shelf Cancer Immunotherapies. |
2021 |
Cells |
Discordant Virus-Specific Antibody Levels, Antibody Neutralization Capacity, and T-cell Responses Following 3 Doses of SARS-CoV-2 Vaccination in a Patient With Connective Tissue Disease. |
2021 |
Open Forum Infect Dis |
Discovery and Mechanism of SARS-CoV-2 Main Protease Inhibitors. |
2021 |
J Med Chem |
Distinct skeletal stem cell types orchestrate long bone skeletogenesis. |
2021 |
Elife |
Doxycycline Significantly Enhances Induction of Induced Pluripotent Stem Cells to Endoderm by Enhancing Survival Through Protein Kinase B Phosphorylation. |
2021 |
Hepatology |
Early-life inflammation primes a T helper 2 cell-fibroblast niche in skin. |
2021 |
Nature |
Efficacy of clinical-grade human placental mesenchymal stromal cells in fetal ovine myelomeningocele repair. |
2021 |
J Pediatr Surg |
Engineering stem cells for cancer immunotherapy. |
2021 |
Trends Cancer |
Enhancing proteasomal processing improves survival for a peptide vaccine used to treat glioblastoma. |
2021 |
Sci Transl Med |
Epigenetic silencing directs expression heterogeneity of stably integrated multi-transcript unit genetic circuits. |
2021 |
Sci Rep |
Fabrication of 3D Cardiac Microtissue Arrays using Human iPSC-Derived Cardiomyocytes, Cardiac Fibroblasts, and Endothelial Cells. |
2021 |
J Vis Exp |
Foxc1 establishes enhancer accessibility for craniofacial cartilage differentiation. |
2021 |
Elife |
Freshly Thawed Cryobanked Human Neural Stem Cells Engraft within Endogenous Neurogenic Niches and Restore Cognitive Function after Chronic Traumatic Brain Injury. |
2021 |
J Neurotrauma |
Global proteomic analyses of human cytotrophoblast differentiation/invasion. |
2021 |
Development |
Harmine inhibits breast cancer cell migration and invasion by inducing the degradation of Twist1. |
2021 |
PLoS One |
Heart Muscle Microphysiological System for Cardiac Liability Prediction of Repurposed COVID-19 Therapeutics. |
2021 |
Front Pharmacol |
Hematopoietic Stem Cell Gene Therapy for Cystinosis: From Bench-to-Bedside. |
2021 |
Cells |
Human induced pluripotent stem cell-derived macrophages ameliorate liver fibrosis. |
2021 |
Stem Cells |
Human limbal epithelial stem cell regulation, bioengineering and function. |
2021 |
Prog Retin Eye Res |
Human neural stem cell-derived extracellular vesicles mitigate hallmarks of Alzheimer’s disease. |
2021 |
Alzheimers Res Ther |
Identification of neural oscillations and epileptiform changes in human brain organoids. |
2021 |
Nat Neurosci |
IFNgamma Is Critical for CAR T Cell-Mediated Myeloid Activation and Induction of Endogenous Immunity. |
2021 |
Cancer Discov |